adam20
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  • Official Full Name
  • ADAM metallopeptidase domain 20
  • Background
  • This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ADAM20; ADAM metallopeptidase domain 20; disintegrin and metalloproteinase domain-containing protein 20; ADAM 20; a disintegrin and metalloproteinase domain 20;
Cat.#:ADAM20-281HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADAM20 Protein, GST-tagged
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Cat.#:ADAM20-3001HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAM20, His-tagged
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Cat.#:ADAM20-9374HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAM20, His-tagged
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Cat.#:ADAM20-7100CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADAM20
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Involved Pathway

ADAM20 involved in several pathways and played different roles in them. We selected most pathways ADAM20 participated on our site, such as Fertilization, Interaction With The Zona Pellucida, Reproduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fertilization
CATSPER2; ZP3; IZUMO4; CATSPER1; HVCN1; TMEM146; CATSPER3; ZP2; ADAM2; IZUMO1
Interaction With The Zona Pellucida
ADAM20; ZP3; ADAM2; ZP2; ADAM30; OVGP1; ADAM21
Reproduction
IZUMO1; ADAM20; HVCN1; IZUMO4; ADAM30; CATSPER1; ZP2; ADAM2; Acr; CATSPER2

Protein Function

ADAM20 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM20 itself. We selected most functions ADAM20 had, and list some proteins which have the same functions with ADAM20. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase activity
Related Protein ADAM9; ADAM10A; MEP1B; ADAMTS20; MMP16; Adam6; ADAMTSL4; PAPPAB; MMP28; C6AST3
Function metallopeptidase activity
Related Protein ADAM5; BMP1B; ADAM28; ADAMTS13; DNPEP; ADAMTS5; NPEPPS; MMP1A; ACY1; DPEP3
Function zinc ion binding
Related Protein RAG2; PRKCG; BPTF; CXXC4; PIAS4; KMT2E; NSMCE1; BAZ1A; WTIP; S100A9

Interacting Protein

ADAM20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM20 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM20.
Dlg4

ADAM20 Related Articles

Zhang, X; Wang, J; et al. EFFECTS OF GINSENOSIDE RG1 OR 17 beta-ESTRADIOL ON A COGNITIVELY IMPAIRED, OVARIECTOMIZED RAT MODEL OF ALZHEIMER'S DISEASE. NEUROSCIENCE 220:191-200(2012).
Parry, DA; Toomes, C; et al. Loss of the Metalloprotease ADAM9 Leads to Cone-Rod Dystrophy in Humans and Retinal Degeneration in Mice. AMERICAN JOURNAL OF HUMAN GENETICS 84:683-691(2009).