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ADAM20

  • Official Full Name

    ADAM metallopeptidase domain 20

  • Overview

    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008]
  • Synonyms

    ADAM20; ADAM metallopeptidase domain 20; disintegrin and metalloproteinase domain-containing protein 20; ADAM 20; a disintegrin and metalloproteinase domain 20;

  • Recombinant Proteins
  • Chicken
  • Homo sapiens (Human)
  • Human
  • E.coli
  • E.coli expression system
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADAM20-281H Recombinant Human ADAM20 Protein, GST-tagged Wheat Germ GST
Human ADAM20-9374H Recombinant Human ADAM20, His-tagged E.coli His 492-693a.a.
Human ADAM20-3001H Recombinant Human ADAM20, His-tagged E.coli His 776
Human ADAM20-0247H Recombinant Human ADAM20 Protein (His367-Gly615), N-His-tagged E.coli N-His His367-Gly615
Homo sapiens (Human) RFL-21744HF Recombinant Full Length Human Disintegrin And Metalloproteinase Domain-Containing Protein 20(Adam20) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (207-726)
Chicken ADAM20-7100C Recombinant Chicken ADAM20 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADAM20 Related Articles

ADAM20 involved in several pathways and played different roles in them. We selected most pathways ADAM20 participated on our site, such as Fertilization, Interaction With The Zona Pellucida, Reproduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FertilizationADAM2;ZP2;CATSPER2;HVCN1;CATSPER1;ZP3;IZUMO1;ADAM30;TMEM146
Interaction With The Zona PellucidaZP3;ADAM20;ADAM2;OVGP1;ADAM30;ADAM21;ZP2
ReproductionCATSPER3;TMEM146;ZP3;CATSPERG2;IZUMO4;CATSPER1;ADAM20;CATSPER2;HVCN1

ADAM20 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM20 itself. We selected most functions ADAM20 had, and list some proteins which have the same functions with ADAM20. You can find most of the proteins on our site.

Function Related Protein
metalloendopeptidase activityAdam6;MMP14;UQCRC2A;C6AST3;ADAMTS13;ADAMTS3;MMP23BB;MMP12;PMPCB
metallopeptidase activityECEL1;ADAM18;ADAM28;CNDP2;NAALAD2;ADAM10A;CLCA5;PSMD14;DPP3
zinc ion bindingRNF44;CAR7;MMP11;CA7;MARCH5L;ZCCHC9;RFWD2;NEURL1AB;LMO3

ADAM20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM20 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM20.

Dlg4

Zhang, X; Wang, J; et al. EFFECTS OF GINSENOSIDE RG1 OR 17 beta-ESTRADIOL ON A COGNITIVELY IMPAIRED, OVARIECTOMIZED RAT MODEL OF ALZHEIMER'S DISEASE. NEUROSCIENCE 220:191-200(2012).
Parry, DA; Toomes, C; et al. Loss of the Metalloprotease ADAM9 Leads to Cone-Rod Dystrophy in Humans and Retinal Degeneration in Mice. AMERICAN JOURNAL OF HUMAN GENETICS 84:683-691(2009).
  • Q&As
  • Reviews

Q&As (7)

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Where is the cellular localization of ADAM20? 07/14/2022

ADAM20 is localized in the cell membrane.

In which diseases is ADAM20 mainly used in research? 04/27/2022

ADAM20 is mainly used in the study of thyroid, colorectal and laryngeal cancers.

What biological processes is ADAM20 involved in? 11/23/2021

ADAM20 is involved in cell adhesion and hydrolysis of various cell surface receptors and proteolysis of signaling molecules.

What is the relationship between ADAM20 and MYCT1? 03/05/2021

MYCT1 negatively regulates the expression of ADAM20.

How is miR-181a related to ADAM20? 03/03/2021

miR-181a directly inhibits the transcription of ADAM20.

Where is ADAM20 predominantly expressed? 11/23/2020

ADAM20 is predominantly expressed in the testis.

What is the biological function of ADAM20? 10/22/2020

ADAM20 has a transmembrane structure and secretory function.

Customer Reviews (3)

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Reviews
06/03/2022

    Timely shipment helped me to get the results of the experiment in the shortest time possible.

    05/17/2022

      The ADAM20 proteins purchased from your company is suitable for ELISA.

      01/25/2022

        Good after-sales service, helped me solve a lot of problems in the experiment.

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