ADAM9
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Official Full Name
ADAM metallopeptidase domain 9
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Overview
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010] -
Synonyms
ADAM9; ADAM metallopeptidase domain 9; MCMP; MDC9; CORD9; Mltng; disintegrin and metalloproteinase domain-containing protein 9; cone rod dystrophy 9; myeloma cell metalloproteinase; cellular disintegrin-related protein; ADAM metallopeptidase domain 9 (meltrin gamma); metalloprotease/disintegrin/cysteine-rich protein 9;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Chicken
- Cynomolgus
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ADAM9-3005H | Recombinant Human ADAM9, His-tagged | E.coli | His | 819 | |
Human | ADAM9-293H | Recombinant Human ADAM9 Protein, GST-tagged | Wheat Germ | GST | ||
Human | ADAM9-311H | Active Recombinant Human ADAM9 Protein, His-tagged | Mammalian cells | His | ||
Human | ADAM9-2422H | Recombinant Human ADAM9 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | ADAM9-0245H | Recombinant Human ADAM9 Protein (Pro440-Gly680), N-His-tagged | E.coli | N-His | Pro440-Gly680 | |
Human | ADAM9-2422H-B | Recombinant Human ADAM9 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Adam9-830M | Recombinant Mouse Adam9 Protein, His-tagged | HEK293 | His | ||
Mouse | ADAM9-1750MCL | Recombinant Mouse ADAM9 cell lysate | Human Cell | N/A | ||
Cynomolgus | ADAM9-1900C | Recombinant Cynomolgus ADAM9 protein, His-tagged | HEK293 | His | Ala 206 - Asp 697 | |
Zebrafish | ADAM9-1386Z | Recombinant Zebrafish ADAM9 | Mammalian Cell | His | ||
Chicken | ADAM9-3047C | Recombinant Chicken ADAM9 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ADAM9 Related Articles
- ADAM9 Related Research Area
ADAM9 involved in several pathways and played different roles in them. We selected most pathways ADAM9 participated on our site, such as Collagen degradation, Degradation of the extracellular matrix, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Collagen degradation | CTSB;CTS7;MMP8;COL9A1;MGC174857;MMP19;COL23A1;COL19A1;MGC174155 |
Degradation of the extracellular matrix | ADAM8;MGC174857;CTSG;MGC174155;FURINA;MMP17;CTSL2;TLL1;ADAM8A |
Extracellular matrix organization | FAM49BA;LOXL4;ADAMTS3;COL28A1;DST;SERPINH1B;LOXL1;MMP20;MFAP2 |
ADAM9 has several biochemical functions, for example, SH3 domain binding, collagen binding, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM9 itself. We selected most functions ADAM9 had, and list some proteins which have the same functions with ADAM9. You can find most of the proteins on our site.
Function | Related Protein |
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SH3 domain binding | KHDRBS3;SH3BP5B;CCDC6;EVL;PTTG1;ADAM9;SH3BGR;ARHGAP17;NCF1 |
collagen binding | ITGA9;LACRT;LUM;CTSK;CTSB;SMAD3;CCBE1;Itga10&Itgb1;SERPINH2 |
integrin binding | TLN1;CYR61L1;ICAM1;S1PR3;VTN;TIMP2;ADAM17;AMICA1;PTPN2 |
laminin binding | PLEKHA2;LGALS1;ECM1;ITGA7;LGALS3;ITGB1;GPC1;NCL;RPSA |
metalloendopeptidase activity | PITRM1;ADAMTS15A;PAPPA;HE2;ECE1;UQCRC1;ECE2;ADAMTS2;MEP1A.2 |
metallopeptidase activity | MMP13A;CPD;HE1B;HE1A;ADAM21;ADAM12;BMP1A;MEP1A.1;PAPPAA |
protein binding | KRTAP19-7;C4orf33;PLP2;NAT10;MPHOSPH6;SYK;TFB1M;TOMM7;TMX3 |
protein kinase C binding | HDAC7;ADD3;SDPRB;DACT3;DSP;PLEK;IRS1;PKN1;TIRAP |
zinc ion binding | CCNB1IP1;CPA6;MMP2;CRIP1;RNF175;TRIM47;ZMAT2;RASGRP1;RAG1 |
ADAM9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM9.
MAD2L2; SH3GL2; PACSIN3; KIF2C
- Q&As
- Reviews
Q&As (12)
Ask a questionYes, we can customize human ADAM9 protein with different purity levels according to your needs.
This need depends on your specific purchase situation.
We currently have only this kind of recombinant mouse Adam9 protein in stock, but we can custom produce Adam9 protein for you.
There is no minimum purchase quantity requirement.
Due to its small molecular weight, His has little effect on the application of proteins, and GST may have some impact on protein functions and downstream experiments.
ADAM9 is also being used in the study of breast cancer, glioma, lung cancer, prostate cancer and other diseases.
ADAM9 expressed mainly in epithelial cells, but also in cells such as inflammatory cells and smooth muscle cells.
ADAM9 can degrade extracellular matrix components such as fibronectin and laminin.
Increased ADAM9 expression is often closely associated with tumour progression and prognosis.
ADAM9 functions in cell adhesion and protein hydrolysis.
There are two forms of ADAM9, soluble ADAM9 molecules and membrane-bound ADAM9.
You can have a detailed communication with our experts who can provide advice according to your research purpose.
Customer Reviews (4)
Write a reviewThe ADAM9 protein product received is as advertised, the quality of the protein is real.
The product was kept intact and delivered in a timely manner, allowing me to get the perfect product in the shortest possible time
The customized ADAM9 met my requirements, and the technicians helped me solve a series of problems in the experiment.
Suitable for WB, with high purity and clear bands.
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