adamts10
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  • Official Full Name
  • ADAM metallopeptidase with thrombospondin type 1 motif, 10
  • Background
  • This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; WMS; WMS1; ADAM-TS10; ADAMTS-10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; zinc metalloendopeptidase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10;
Cat.#:ADAMTS10-1759HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAMTS10 protein, His & T7-tagged
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Cat.#:ADAMTS10-297HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAMTS10 Protein
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Cat.#:ADAMTS10-1308MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADAMTS10 Protein
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Cat.#:Adamts10-3010MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Adamts10, His-tagged
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Cat.#:ADAMTS10-235RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADAMTS10 Protein, His-tagged
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Cat.#:ADAMTS10-6664ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ADAMTS10
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Cat.#:ADAMTS10-9032HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ADAMTS10 293 Cell Lysate
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Involved Pathway

ADAMTS10 involved in several pathways and played different roles in them. We selected most pathways ADAMTS10 participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
EEF1D; IGFBP2B; COX17; PHC1; PHC3; SPON1B; CEACAM21; MCFD2; ADAMTSL4; EIF5
O-glycosylation of TSR domain-containing proteins
ADAMTS5; C8orf84; THSD7A; SPON2; SPON1A; ADAMTS18; ADAMTSL4; SSPO; ADAMTS13; SPON1B
O-linked glycosylation
SSPO; ADAMTSL1; SPON1; B3GNT8; C8orf84; MUC1; A4GNT; GALNTL5; MUC5AC; B3GNT2A
Post-translational protein modification
TRAPPC4; SENP1; ADAMTS4; ST6GALNAC2; SMC6; MPDU1; OTOP2; NSMCE1; ATPBD4; ALG10B

Protein Function

ADAMTS10 has several biochemical functions, for example, metalloendopeptidase activity, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS10 itself. We selected most functions ADAMTS10 had, and list some proteins which have the same functions with ADAMTS10. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase activity
Related Protein ADAMTS13; MMP19; Adamts19; ADAM17; ADAMTS16; MMP3; MMP2; ADAM30; YME1L1B; THOP1
Function molecular_function
Related Protein ARL14EPL; FAM174B; PXT1; PRAMEL4; SDR42E1; PRL5A1; GSDMC2; TIMM21; OTULINA; TMEM22
Function protein binding
Related Protein LCMT1; MRPS31; KCNN4; CALCR; KAL1; ICA1; FBLN1; NUP50; GMCL1P1; DERL2
Function zinc ion binding
Related Protein MME; GATAD2A; VDRB; ADAM28; BMI1B; TLL1; PDZRN3; TAF3; KPNB1; KDM1B

Interacting Protein

ADAMTS10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS10.
TK1; ANXA7; HMGCL; CDKN1A; SMN1; PCYT2; LAMTOR3