ADAMTS15
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Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 15
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Overview
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the proteins encoded by ADAMTS1 and ADAMTS8. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS15; ADAM metallopeptidase with thrombospondin type 1 motif, 15; A disintegrin and metalloproteinase with thrombospondin motifs 15; ADAM-TS15; ADAMTS-15; ADAM-TS 15; metalloprotease disintegrin 15 with thrombospondin domains; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15, preproprotein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- CHO
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ADAMTS15-528H | Active Recombinant Human ADAM Metallopeptidase With Thrombospondin type 1 Motif, 15, His-tagged | CHO | His |
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| Human | ADAMTS15-300H | Recombinant Human ADAMTS15 Protein, GST-tagged | Wheat Germ | GST |
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| Human | ADAMTS15-9031HCL | Recombinant Human ADAMTS15 293 Cell Lysate | HEK293 | N/A |
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| Mouse | ADAMTS15-1312M | Recombinant Mouse ADAMTS15 Protein | Mammalian Cell | His |
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| Mouse | Adamts15-3011M | Recombinant Mouse Adamts15, His-tagged | E.Coli or Yeast | His | 950 |
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| Mouse | ADAMTS15-324M | Recombinant Mouse ADAMTS15 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ADAMTS15-324M-B | Recombinant Mouse ADAMTS15 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ADAMTS15 Related Articles
- ADAMTS15 Related Research Area
ADAMTS15 involved in several pathways and played different roles in them. We selected most pathways ADAMTS15 participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | SLC35A1;IGFBP2;TOMM20;EIF5A2;TRAPPC6BL;PREB;FKBP9;NEU4;APCS |
| O-glycosylation of TSR domain-containing proteins | ADAMTS20;C8orf84;B3GALTL;ADAMTSL1;ADAMTS8;ADAMTS18;THSD7A;ADAMTS5;ADAMTSL4 |
| O-linked glycosylation | B3GNT6;THSD1;ADAMTS20;MUCL1;ADAMTS8;MUC21;A4GNT;ADAMTS1;SPON1 |
| Post-translational protein modification | TFG;DPH2;LMAN2;MGAT4A;WDR85;PREB;B3GNT6;ARSD;MUC1 |
ADAMTS15 has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS15 itself. We selected most functions ADAMTS15 had, and list some proteins which have the same functions with ADAMTS15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | ADAMDEC1;ADAM15;MIPEP;THOP1;ADAM21;ADAM10B;ECEL1;ADAM25;TLL2 |
| zinc ion binding | RCHY1;TRIM62;CBLL1;TRIM22;ADAMTS4;GRIN2A;MMP13;ADAM5;CSRP1B |
ADAMTS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS15.
- Q&As
- Reviews
Q&As (7)
Ask a questionExpression of ADAMTS15 inhibits tumor growth and invasion.
ADAMTS15 is mainly expressed in liver and kidney tissues.
We can remove tags according to your needs.
ADAMTS15 has the function of inhibiting tumor growth and vascular synthesis.
ADAMTS15 is currently focused on rectal and breast cancer studies.
Does His tag have a great influence on the activity of ADAMTS15?
Does His tag have a great influence on the activity of ADAMTS15?
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