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ADAMTSL3

  • Official Full Name

    ADAMTS-like 3

  • Synonyms

    ADAMTSL3; ADAMTS-like 3; ADAMTS-like protein 3; KIAA1233; punctin 2; ADAMTSL-3; punctin-2; a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like 3; MGC150716; MGC150717;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADAMTSL3-924H Recombinant Human ADAMTSL3 Mammalian Cell His
Human ADAMTSL3-312H Recombinant Human ADAMTSL3 Protein, GST-tagged Wheat Germ GST
Human ADAMTSL3-3149H Recombinant Human ADAMTSL3, His-tagged E.Coli or Yeast His 1691
Human ADAMTSL3-2426H-B Recombinant Human ADAMTSL3 Protein Pre-coupled Magnetic Beads HEK293
Human ADAMTSL3-2426H Recombinant Human ADAMTSL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ADAMTSL3-3672H Recombinant Human ADAMTSL3 protein, GST-tagged E.coli GST 616-720 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ADAMTSL3 involved in several pathways and played different roles in them. We selected most pathways ADAMTSL3 participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTSL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsDAD1;LMCD1;CPA3;EEF1A2;LMAN2L;KDELR3;TFG;CST3;TIMM9
O-glycosylation of TSR domain-containing proteinsSPON1B;ADAMTS20;ADAMTS18;ADAMTS8;ADAMTS13;ADAMTSL4;ADAMTS15;ADAMTSL3;C8orf84
O-linked glycosylationMUC5AC;MUC12;THSD7A;GALNT5;GALNTL5;ADAMTS4;ADAMTS15;ADAMTS3;SPON1A
Post-translational protein modificationYKT6;SCMH1;ADAMTS8;ADAMTS5;MUC5AC;ARSD;NSMCE1;RNF2;DPAGT1

ADAMTSL3 has several biochemical functions, for example, metallopeptidase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTSL3 itself. We selected most functions ADAMTSL3 had, and list some proteins which have the same functions with ADAMTSL3. You can find most of the proteins on our site.

Function Related Protein
metallopeptidase activityMMP2;MYSM1;PGCP;ADAMTS1;AGBL1;ADAMTS16;NPEPPS;DPP3;DPEP3
protein bindingTET2;GFM1;CDC42EP2;AHR;GPA33;EIF4B;RNF126;DNMBP;KIF3A
zinc ion bindingMUL1B;ADAMTS9;NEURL1AB;ZDHHC18;PRDM2;RBM14A;ZNFL1;RNF114;MICAL1

ADAMTSL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTSL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTSL3.

KRTAP2-3; KRTAP10-8; KRT40; NOTCH2NL; MDFI

  • Q&As
  • Reviews

Q&As (15)

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What methods can be used to measure ADAMTSL3 protein levels? 01/19/2022

ADAMTSL3 protein levels can be measured using a range of laboratory techniques including ELISA, Western blotting, and mass spectrometry. More advanced imaging techniques such as immunohistochemistry and confocal microscopy can also be used to visualize ADAMTSL3 expression in cells and tissues.

Can ADAMTSL3 protein be used to treat cardiovascular disease? 12/14/2021

Research into the role of ADAMTSL3 in cardiovascular disease is ongoing. While there is currently no evidence to suggest that ADAMTSL3 protein can be used to treat cardiovascular disease, future research may identify potential therapeutic targets.

How is ADAMTSL3 protein studied in the laboratory? 10/06/2021

ADAMTSL3 protein can be studied using various techniques such as western blotting, immunohistochemistry, and gene expression analysis. Animal models, such as knockout mice and xenograft models, can also be used to study the role of ADAMTSL3 in disease development and its potential as a therapeutic target. Additionally, in vitro experiments can be performed using cell lines to study the effects of ADAMTSL3 on cellular processes such as cell adhesion, migration, and proliferation.

What are some other members of the ADAMTS protein family? 02/16/2021

The ADAMTS protein family comprises 19 members, including ADAMTS1-18 and ADAMTSL1-5. These proteins are involved in a diverse range of processes including ECM assembly and remodeling, angiogenesis, inflammation, and coagulation.

Can ADAMTSL3 protein be used to treat connective tissue disorders? 09/22/2020

At present, there is no evidence to suggest that ADAMTSL3 protein can be used to treat connective tissue disorders. However, research into the role of ADAMTSL3 in connective tissue biology is ongoing.

What are the physiological functions of ADAMTSL3 protein? 05/20/2019

ADAMTSL3 protein is involved in the regulation of cellular processes such as cell adhesion, migration, and proliferation, as well as various developmental processes and tissue homeostasis. ADAMTSL3 also plays a role in the formation and maintenance of extracellular matrix structures such as connective tissues, cartilage, and bone.

Can ADAMTSL3 protein be used to improve wound healing? 09/07/2018

There is currently no evidence to suggest that ADAMTSL3 protein can improve wound healing. However, ongoing research into the role of ADAMTSL3 in tissue repair may identify potential therapeutic targets for enhancing wound healing.

What therapeutic applications are being explored for ADAMTSL3 protein? 07/06/2018

While there are no current therapeutic applications for ADAMTSL3 protein, research is being conducted to determine potential therapeutic targets for various medical conditions.

What role does ADAMTSL3 protein play in cancer? 03/26/2018

ADAMTSL3 has been implicated in various cancer types since it is involved in the regulation of cell adhesion, migration, and proliferation. Studies have shown that there is a decreased expression of ADAMTSL3 in several types of cancers such as breast, prostate, colon, and ovarian cancer. Its downregulation is correlated with advanced tumor stage, invasion, and poor prognosis.

Can ADAMTSL3 protein be used as a therapeutic target in cancer? 02/02/2018

The reduced expression of ADAMTSL3 in cancer cells suggests that it may play a role in tumor development and progression. Therefore, ADAMTSL3 protein may serve as a promising therapeutic target in cancer. Preclinical studies have shown that upregulation of ADAMTSL3 can inhibit cancer cell proliferation, invasion, and metastasis.

Is ADAMTSL3 protein expressed in specific tissues or cell types? 05/04/2017

ADAMTSL3 protein is expressed in a range of tissues including the heart, lungs, kidneys, and skeletal muscle. It is also expressed in a number of cell types including fibroblasts, smooth muscle cells, and endothelial cells.

Can ADAMTSL3 protein be used to treat muscular disorders? 08/08/2016

At present, there is no evidence to suggest that ADAMTSL3 protein can be used to treat muscular disorders. However, ongoing research into the role of ADAMTSL3 in muscle biology may identify potential therapeutic targets.

Can ADAMTSL3 protein be used to prevent or treat cancer? 11/18/2015

While there is evidence to suggest that ADAMTSL3 is involved in tumor development and metastasis, it is unclear whether ADAMTSL3 protein could be used to prevent or treat cancer. Further research is required to determine if ADAMTSL3 protein could be a viable therapeutic target in cancer treatment.

Are there any drugs currently available that target ADAMTSL3 protein? 07/03/2015

At present, there are no drugs specifically targeting ADAMTSL3 protein. However, there are drugs that target other proteins involved in connective tissue biology, some of which may be relevant to ADAMTSL3-related conditions.

Are there any ongoing clinical trials involving ADAMTSL3 protein? 05/01/2015

At present, there are no ongoing clinical trials specifically targeting ADAMTSL3 protein. However, there are several clinical trials investigating the use of drugs that target the ECM and fibrillin in various connective tissue disorders, some of which may be relevant to ADAMTSL3-related conditions.

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