adrb3
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  • Official Full Name
  • adrenergic receptor, beta 3
  • Background
  • The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate;catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located;mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis.
  • Synonyms
  • ADRB3; adrenergic receptor, beta 3; beta-3 adrenergic receptor; ADR B3; ADRB 3; ADRB3_HUMAN; ADRB3R; Adrenergic beta 3 receptor; B3AR; Beta 3 adrenoceptor; Beta 3 adrenoreceptor; Beta 3AR; Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta3AR; FLJ99960; Beta-3 AR; beta 3-AR; OTTMUSP00000036279; beta3-adrenergic receptor; Adrb-3
Cat.#:ADRB3-147HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ADRB3
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Cat.#:ADRB3-382HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADRB3 Protein, GST-tagged
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Cat.#:ADRB3-1387MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADRB3 Protein
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Cat.#:ADRB3-545RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ADRB3 Protein
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Cat.#:ADRB3-281CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ADRB3 Protein, His-tagged
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Cat.#:ADRB3-261RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADRB3 Protein, His-tagged
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Cat.#:ADRB3-8998HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ADRB3 293 Cell Lysate
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Involved Pathway

ADRB3 involved in several pathways and played different roles in them. We selected most pathways ADRB3 participated on our site, such as Adrenoceptors, Amine ligand-binding receptors, Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adrenoceptors
ADRB3; ADRa1A; ADRA1D; ADRA2A; ADRA1B; ADRB2; ADRB1; ADRA2B; ADRA2C
Amine ligand-binding receptors
ADRA2A; DRD1; CHRM1; CHRM2; CHRM3; DRD3; ADRA1B; DRD4; ADRA2C; DRD5
Calcium Regulation in the Cardiac Cell
GJA4; ADRB2; RGS6; ADRB3; GJB4; RGS5; GJC1; RGS17; RGS10; GJB5
Calcium signaling pathway
ITPKA; SLC8A1A; CAMK2G; PRKCBA; TRHR2; DRD5; PDE1C; SLC8A2B; PRKACB; MLCK2
Class A/1 (Rhodopsin-like receptors)
GPR39; FPR-RS4; SSTR4; GRP; PROK1; HCRT; PROKR1; GPR55A; CCR5; PPY
Endocytosis
SNX1B; PARD6GB; ARPC5; CBLC; ARFGAP2; RAB11FIP4A; KDRL; SMURF2; VPS26B; EHD1A
G alpha (s) signalling events
SCT; TAAR1; ADCYAP1; CALCB; CRH; NPS; ADRB3; CRHR1; CALCA; ADCYAP1B
GPCR downstream signaling
NPS; GHRH; GPR65; SSTR1; LPAR2B; SSTR3; RGS19; CXCL13; OR2AP1; RGS21

Protein Function

ADRB3 has several biochemical functions, for example, beta-3 adrenergic receptor binding, beta-adrenergic receptor activity, beta3-adrenergic receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRB3 itself. We selected most functions ADRB3 had, and list some proteins which have the same functions with ADRB3. You can find most of the proteins on our site.
Function
Related Protein
Function beta-3 adrenergic receptor binding
Related Protein ADRB3; ARRDC3
Function beta-adrenergic receptor activity
Related Protein ADRB1; ADRB3
Function beta3-adrenergic receptor activity
Related Protein ADRB3A; ADRB3B; ADRB3
Function epinephrine binding
Related Protein ADRB2; ADRA2A; ADRB1; ADRB3B; ADRB2A; ADRA2B; ADRB3A; ADRB2B; ADRA2C; ADRB3
Function contributes_to norepinephrine binding
Related Protein ADRB3
Function protein binding
Related Protein HSPA5; SMO; FAM127C; VHLL; FAM110A; TNKS2; CRY1A; GOSR2; C1orf189; S100A11
Function protein homodimerization activity
Related Protein APOC2; IRAK1; SLC22A6; PGCP; GSTM1; BAX; DMRTA2; AADAT; RPS19; ALS2

Interacting Protein

ADRB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRB3.
Cav3; Nos3; Nos1