AGAP3
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Official Full Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
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Overview
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene. -
Synonyms
AGAP3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; centaurin, gamma 3 , CENTG3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3; ANK repeat and PH domain-containing protein 3; AGAP-3; AGAP3_HUMAN; Arf GAP with GTPase, ANK repeat and PH domain containing protein 3; Arf-GAP with GTPase; ArfGAP with GTPase domain, ankyrin repeat and PH domain; centaurin gamma 3; Centaurin-gamma-3; CENTG3; Cnt-g3; CRAG; CRAM-associated GTPase; CRMP (collapsin response mediator protein) associated; FLJ16146; FLJ34452; MR1-interacting protein; MRIP-1; MRIP1; OTTHUMP00000213333; OTTHUMP00000213334; OTTHUMP00000213335; OTTHUMP00000213336; OTTHUMP00000213337; centaurin, gamma 3;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | AGAP3-541H | Recombinant Human AGAP3 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | AGAP3-0009H | Recombinant Human AGAP3 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | AGAP3-301203H | Recombinant Human AGAP3 protein, GST-tagged | E.coli | GST | Leu474-Thr556 |
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| Mouse | Agap3-1551M | Recombinant Mouse Agap3 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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AGAP3 involved in several pathways and played different roles in them. We selected most pathways AGAP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AGAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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AGAP3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AGAP3 itself. We selected most functions AGAP3 had, and list some proteins which have the same functions with AGAP3. You can find most of the proteins on our site.
| Function | Related Protein |
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AGAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGAP3.
- Q&As
- Reviews
Q&As (23)
Ask a questionYes, AGAP3 belongs to a family of Arf GTPase-activating proteins (ArfGAPs) that share similar structural domains.
Yes, AGAP3 expression can vary between different tissues and cell types.
AGAP3 is primarily located in the cytoplasm of cells.
The molecular weight of AGAP3 is approximately 150 kDa.
Yes, AGAP3's involvement in vesicle trafficking is crucial for neuronal development and synaptic function.
AGAP3 is a protein that plays a role in intracellular trafficking and membrane dynamics.
AGAP3's involvement in vesicle trafficking and cell migration can contribute to tumor growth and metastasis in certain cancers.
AGAP3 acts as a GTPase-activating protein (GAP) for Arf GTPases, regulating their activity in intracellular trafficking pathways.
AGAP3 participates in endocytic processes by regulating the formation and trafficking of endocytic vesicles.
AGAP3's expression can be regulated by various factors, including cellular signaling pathways and transcriptional regulators.
The PH domain in AGAP3 is thought to be involved in membrane targeting and interaction with phospholipids.
AGAP3 influences cell migration by regulating the turnover of adhesion complexes and actin dynamics.
AGAP3 is involved in vesicle trafficking, endocytosis, and cell migration.
AGAP3 stands for Arf-GAP with GTPase domain, Ankyrin repeat, and PH domain 3.
Yes, AGAP3's function can be influenced by factors such as post-translational modifications and protein interactions.
The Ankyrin repeat in AGAP3 is believed to play a role in protein-protein interactions.
Researchers use techniques like molecular biology, microscopy, and cell culture experiments to study AGAP3's role in cells.
AGAP3 helps regulate the movement of vesicles within cells, aiding in the transportation of molecules.
Mutations in AGAP3 have been linked to certain neurological disorders and cancer progression.
Yes, AGAP3 can be found in various subcellular compartments, including the plasma membrane, endosomes, and Golgi apparatus.
Yes, AGAP3 can impact signal transduction pathways by regulating membrane trafficking of receptors and signaling molecules.
AGAP3's GAP activity is often activated by interactions with activated Arf GTPases, triggering the hydrolysis of GTP to GDP.
Knocking down or inhibiting AGAP3 can lead to disrupted vesicle trafficking, altered cell adhesion, and changes in cellular morphology.
Customer Reviews (5)
Write a reviewThe product’s high purity facilitated precise quantification, minimizing variability in our data.
Agap3's absence of contaminants contributed to data accuracy.
The product’s innovative characteristics allowed us to delve into previously unexplored cellular mechanisms.
The consistent effects of Agap3 streamlined our research process.
It triggered a robust immune response, evident in cytokine levels.
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