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AGK

  • Official Full Name

    acylglycerol kinase

  • Overview

    Acylglycerol kinase, mitochondrial is an enzyme that in humans is encoded by the AGK gene.
  • Synonyms

    AGK; acylglycerol kinase; MULK, multiple substrate lipid kinase; acylglycerol kinase, mitochondrial; FLJ10842; 6720408I04Rik; mitochondrial; 2610037M15Rik; Acylglycerol kinase mitochondrial; AGK_HUMAN; AI465370; hAGK; HsMuLK; MULK; Multi substrate lipid kinase; Multi-substrate lipid kinase; Multiple substrate lipid kinase; RGD1562046;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AGK-1155HCL Recombinant Human AGK cell lysate N/A
Human AGK-5753H Recombinant Human AGK Protein, GST-tagged Wheat Germ GST
Human AGK-411H Recombinant Human AGK Protein, His/GST-tagged E.coli His/GST Thr15~Pro300
Human AGK-6524HF Recombinant Full Length Human AGK Protein, GST-tagged In Vitro Cell Free System GST 422 amino acids
Human AGK-0098H Recombinant Human AGK Protein (Thr15-Pro300), N-GST-tagged E.coli N-GST Thr15-Pro300
Mouse AGK-1415M Recombinant Mouse AGK Protein Mammalian Cell His
Mouse AGK-387M-B Recombinant Mouse AGK Protein Pre-coupled Magnetic Beads HEK293
Mouse AGK-387M Recombinant Mouse AGK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque AGK-270R Recombinant Rhesus monkey AGK Protein, His-tagged Mammalian Cell His
Rhesus Macaque AGK-98R-B Recombinant Rhesus Macaque AGK Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque AGK-98R Recombinant Rhesus Macaque AGK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish AGK-10252Z Recombinant Zebrafish AGK Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AGK Related Articles

AGK involved in several pathways and played different roles in them. We selected most pathways AGK participated on our site, such as Glycerolipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerolipid metabolismMGLL;PNLIPRP2;AKR1B1;ALDH2.1;ALDH2;AKR1B10;PPAP2D;Akr1b3;MOGAT3
Metabolic pathwaysPLCD1;NMRK2;SDHC;DPYD;NDST3;TBXAS1;NOS3;ALOX5;FPGS

AGK has several biochemical functions, for example, ATP binding, acylglycerol kinase activity, ceramide kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGK itself. We selected most functions AGK had, and list some proteins which have the same functions with AGK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingHSPH1;PSMC1;PAK2A;Aatk;NIM1;DYRK2;ENTPD3;KARS;SNRK
acylglycerol kinase activity
ceramide kinase activityCERK;AGK
diacylglycerol kinase activityAGK;DGKB;DGKQ;DGKAA;DGKG;DGKZ;DGKD;TAE1;DGKA

AGK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGK here. Most of them are supplied by our site. Hope this information will be useful for your research of AGK.

pi3p; MYC; ICT1; P; AGO4

Yang, WN; Lin, Q; et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta(1). JOURNAL OF BIOLOGICAL CHEMISTRY 274:8524-8530(1999).
  • Q&As
  • Reviews

Q&As (20)

Ask a question
Can AGK be a therapeutic target? 06/25/2022

Research explores AGK's potential as a target for treating mitochondrial diseases.

How does AGK contribute to cellular energy production? 06/24/2022

AGK's involvement in mitochondrial function affects energy production processes.

How does AGK influence cell signaling? 04/21/2022

AGK participates in regulating cell signaling pathways through its nucleotide exchange activity.

Is AGK relevant to lipid metabolism? 03/08/2022

Yes, AGK's roles might intersect with lipid metabolism pathways.

What's the connection between AGK and mitochondrial disorders? 02/03/2022

AGK mutations are associated with mitochondrial diseases impacting energy production.

What is the AGK protein? 12/23/2021

AGK stands for "A-type guanine nucleotide exchange factor," involved in cellular processes.

How is AGK's structure characterized? 10/08/2021

AGK has a distinctive protein structure that contributes to its cellular functions.

How do AGK mutations impact mitochondrial function? 12/06/2020

AGK mutations disrupt mitochondrial function, leading to energy production deficits.

How does AGK's nucleotide exchange activity work? 10/03/2020

AGK's nucleotide exchange activity modulates the activity of GTPase proteins.

How does AGK impact membrane dynamics? 08/25/2020

AGK's functions contribute to the dynamic changes in cellular membranes.

What's the significance of AGK mutations? 09/15/2019

Mutations in AGK can lead to mitochondrial disorders and related symptoms.

How does AGK relate to cardiomyopathies? 05/31/2019

AGK mutations are associated with certain types of cardiomyopathies.

Can AGK's activities influence mitochondrial morphology? 03/29/2019

AGK's functions could impact mitochondrial shape and dynamics.

What are the applications of AGK? 01/08/2019

AGK's functions impact cell signaling, vesicle trafficking, and membrane dynamics.

Is AGK's research ongoing? 10/12/2018

Yes, ongoing research uncovers AGK's multifaceted roles and potential implications.

Can AGK's roles extend to cellular apoptosis? 09/24/2018

Research investigates whether AGK is involved in regulating cellular apoptosis.

Does AGK influence cellular oxidative stress responses? 07/09/2018

AGK's functions might intersect with cellular responses to oxidative stress.

Can AGK affect intracellular trafficking? 06/08/2018

AGK's roles extend to intracellular trafficking processes and vesicle transport.

Can AGK regulate vesicle trafficking? 03/20/2018

Yes, AGK plays a role in vesicle trafficking, affecting cellular cargo transport.

Are there disease implications for AGK? 02/24/2018

Mutations in AGK are linked to diseases involving mitochondrial dysfunction.

Customer Reviews (5)

Write a review
Reviews
06/22/2022

    Protein AGK's reliable results helped us uncover key signaling pathways in our experiments.

    09/05/2021

       The protein product’s ability to induce apoptosis provided valuable insights into cell mechanisms.

      08/04/2017

         The protein product’s compatibility with diverse buffer systems ensured stable performance.

        04/27/2017

           The protein product consistently behaved as expected, reinforcing our experimental conclusions.

          02/11/2016

            The high purity of AGK ensured accurate quantification of protein levels.

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