AGPAT3
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Official Full Name
1-acylglycerol-3-phosphate O-acyltransferase 3
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Overview
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; LPAAT gamma; 1-AGP acyltransferase 3; 1-AGPAT 3; acyltransferase gamma; LPAAT-gamma; Lysophosphatidic acid acyltransferase gamma; UNQ759/PRO1490; lysophosphatidic acid acyltransferase-gamma1; LPAAT-GAMMA1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | AGPAT3-430H | Recombinant Human AGPAT3 Protein, GST-tagged | Wheat Germ | GST |
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| Human | AGPAT3-431H | Recombinant Human AGPAT3 Protein, GST-tagged | Wheat Germ | GST |
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| Human | AGPAT3-8976HCL | Recombinant Human AGPAT3 293 Cell Lysate | HEK293 | N/A |
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| Human | AGPAT3-3665H | Recombinant Human AGPAT3 protein, His-tagged | E.coli | His | 326-376 aa | |
| Human | AGPAT3-931HF | Recombinant Full Length Human AGPAT3 Protein, GST-tagged | In Vitro Cell Free System | GST | 63 amino acids |
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| Homo sapiens (Human) | RFL28489HF | Recombinant Full Length Human 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma(Agpat3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-376) |
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| Mus musculus (Mouse) | RFL23182MF | Recombinant Full Length Mouse 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma(Agpat3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-376) |
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| Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL27810PF | Recombinant Full Length Pongo Abelii 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma(Agpat3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-376) |
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| Zebrafish | AGPAT3-12597Z | Recombinant Zebrafish AGPAT3 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- AGPAT3 Related Articles
AGPAT3 involved in several pathways and played different roles in them. We selected most pathways AGPAT3 participated on our site, such as Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGPAT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | LYCAT;ALDH9A1B;MBOAT1;MBOAT2;AGPAT3;ALDH2.2;DGKE;AKR1A1;PNPLA2 |
| Glycerophospholipid metabolism | DGKG;PLA2G12B;LYCAT;LCAT;PLA2G2E;DGKAA;TESCA;CHKB;PLA2G1B |
| Metabolic pathways | BCAT1;SCLY;GANAB;HGD;LIPF;CYP3A25;TPO;PIGP;AMY2A3 |
| Phospholipase D signaling pathway | PLA2G4A;PLA2G4F;LPAR3;PRKCA;AKT1;AVPR2;PIP5K1A;SYK;GAB2 |
AGPAT3 has several biochemical functions, for example, 1-acylglycerol-3-phosphate O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGPAT3 itself. We selected most functions AGPAT3 had, and list some proteins which have the same functions with AGPAT3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase activity | AGPAT9;AGPAT3;AGPAT5;AGPAT9L;AGPAT1;LPCAT2;AGPAT4;AGPAT2;LYCAT |
AGPAT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGPAT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGPAT3.
CREB3; valS
- Q&As
- Reviews
Q&As (22)
Ask a questionYes, AGPAT3’s involvement helps generate a diverse range of phospholipids for various cellular functions.
Yes, AGPAT3 is a potential target for modulating lipid metabolism and related diseases.
Yes, AGPAT3’s function can be influenced by cellular stress and changes in metabolic state.
Yes, mutations in AGPAT3 can result in metabolic disorders affecting lipid metabolism and cellular health.
Yes, AGPAT3’s activity can be regulated by intracellular signals that impact lipid metabolism.
AGPAT3’s role in lipid metabolism contributes to maintaining lipid balance and cellular health.
AGPAT3’s involvement can impact the physical and chemical properties of cellular membranes.
Yes, AGPAT3’s activity might impact inflammation through its influence on lipid metabolism.
Research explores whether AGPAT3’s function is conserved across different organisms.
Research explores AGPAT3’s impact on the lipid composition and profiles of cellular membranes.
AGPAT3 contributes to the synthesis of new phospholipids and the remodeling of existing ones.
Yes, AGPAT3’s function contributes to the synthesis of cellular membranes and lipid bilayers.
AGPAT3’s role in lipid metabolism can influence the production of lipid signaling molecules.
AGPAT3’s activity can impact cellular susceptibility to lipotoxicity and lipid-induced damage.
Yes, AGPAT3’s function is linked to energy storage and utilization through lipid metabolism.
Yes, AGPAT3’s function can influence the formation and dynamics of lipid droplets in cells.
AGPAT3’s role in lipid biosynthesis influences the composition and fluidity of cellular membranes.
AGPAT3 is primarily located in the endoplasmic reticulum (ER) membrane.
Yes, AGPAT3’s role in lipid metabolism can impact intercellular communication and signaling.
Yes, AGPAT3’s function can contribute to cell survival through lipid metabolism pathways.
Research investigates AGPAT3’s function using biochemical assays and cellular experiments.
Research investigates how AGPAT3’s activity affects the stability and integrity of lipid bilayers.
Customer Reviews (5)
Write a reviewThe product’s innovative traits allowed us to explore previously unknown cellular processes.
Replicating results confirmed the product’s reliability and significance in our research.
The knowledge gained from the product justified its cost, offering substantial value for investment.
Feel free to continue expanding your list by adding these reviews to your Excel sheet.
The product’s consistent outcomes reinforced the reproducibility of our scientific investigations.
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