Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

AGTR1A

  • Official Full Name

    angiotensin II receptor, type 1a

  • Synonyms

    AGTR1A; angiotensin II receptor, type 1a; type-1A angiotensin II receptor; Angiotensin II type 1a receptor; AT1; AT1A; AT1AR; Type 1 angiotensin II receptor; OTTMUSP00000000614; angiotensin receptor 1; angiotensin receptor 1a; angiotensin II type-1A receptor; AG2S; AT2R1; Agtr1; AT2R1A; Agtr-1a; AI551199; Angtr-1a; 1810074K20Rik;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse AGTR1A-1430M Recombinant Mouse AGTR1A Protein Mammalian Cell His
Mouse AGTR1A-397M Recombinant Mouse AGTR1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse AGTR1A-397M-B Recombinant Mouse AGTR1A Protein Pre-coupled Magnetic Beads HEK293
Rat AGTR1A-566R Recombinant Rat AGTR1A Protein Mammalian Cell His
Rat Agtr1a-1768R Recombinant Rat Agtr1a protein, His & GST-tagged E.coli His/GST Asp263~Glu359 (Accession # P25095)
Rat AGTR1A-222R Recombinant Rat AGTR1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AGTR1A-222R-B Recombinant Rat AGTR1A Protein Pre-coupled Magnetic Beads HEK293
Mus musculus (Mouse) RFL-2154MF Recombinant Full Length Mouse Type-1A Angiotensin Ii Receptor(Agtr1A) Protein, His-Tagged E.coli expression system His Full Length (1-359AA)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AGTR1A Related Signal Pathway

AGTR1A involved in several pathways and played different roles in them. We selected most pathways AGTR1A participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGTR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayGRM1;CACNA1DA;CYSLTR1;ADRB3A;HTR2B;ATP2A2B;SLC8A1A;TACR3L;PRKCB
cGMP-PKG signaling pathwayMAPK3;IRS2;PPP3R2;PLCB1;MEF2C;CALML5;MAP2K1;PRKG2;KCNMB3
Phospholipase D signaling pathwayCYTH4;LPAR2;GRM4;PLCG1;PDGFB;PLD2;LPAR6;FCER1G;GAB2
Neuroactive ligand-receptor interactionTBXA2R;TAAR12G;TAAR14B;CNR2;F2RL3;CALCR;F2R;PRP2;PTGER4C
Adrenergic signaling in cardiomyocytesADCY2B;SCN5A;AKT1;PPP2R5EA;PPP1CB;CACNG6;CAMK2D1;CACNB1;MAPK14
Vascular smooth muscle contractionKCNMB3;CYP4A12A;ACTG2;PRKG1A;PRKCHA;CACNA1C;PLA2G1B;PLA2G4A;MYLK4
Renin-angiotensin systemKLK1;MRGPRD;MAS1;KLK1B1;CPA3;ACE;KLK1B22;ATP6AP2;KLK1B5
Renin secretionACE;CALM4;PDE3B;ORAI1;CLCA2;Ren1;PRKACG;CALML3;REN
Aldosterone synthesis and secretionADCY8;CAMK2A;AGTR1B;NR4A1;ATF1;LIPE;NPR1;CREB3;ITPR3
Pathways in cancerWNT1;FOXO1;MSH3;BMP4;IL6;FGF3;STAT3;PRKACG;LAMB2

AGTR1A has several biochemical functions, for example, D1 dopamine receptor binding, G-protein alpha-subunit binding, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGTR1A itself. We selected most functions AGTR1A had, and list some proteins which have the same functions with AGTR1A. You can find most of the proteins on our site.

Function Related Protein
D1 dopamine receptor bindingDLG4;AGTR1A;CAV2;GNAS;ARRB2;DRD3;PTPN11;ATP1A3
G-protein alpha-subunit bindingRGS4;RIC8A;DRD1;DRD1A;HTR2B;AGTR1A;RIC8B;HTR2A;F2RL1
G-protein coupled receptor activityRXFP2A;TAAR10A;OLFR488;SETD6;TACR1A;O3far1;GPR65;GPR26;HTR1E
angiotensin type I receptor activityAGTR1B;AGTR1;AGTR1A
angiotensin type II receptor activityRXFP3.2B;AGTR1B;APLNRA;AGTR1A;AGTR2;CXCR3.2;APLNRB;RXFP4;AGTRAP
bradykinin receptor bindingAGTR1;ACE;AGTR1A
peptide hormone bindingGCGR;RXFP2;GIPR;PTH1R;INHBA;ECE1;PTH1RA;SLC40A1;NPR2
protein bindingUBE2H;RAD51;AGBL4;HSD17B8;MPP2;HNF4A;LTC4S;NEK6;NOTCH2
protein heterodimerization activityPRPH;KCNB2;SYT5;HIST1H2B7;SNX6;GTF2A1;SOX17;MCL1A;SMAD1
protein kinase bindingTICAM1;TSKS;GOLGA2;FGR;ARHGEF7;IL12RB2;GPRC5B;MAVS;TRAF4
protein self-associationCTSC;TTN;SLC9A3R1;ZFP639;TMEM190;PABPN1;VAMP2;ACVR2A;CCDC88C
signal transducer activityGPR183A;OLFR502;SHC3;TRIM55;GNAO1B;TAS2R126;FPR-RS6;PLCXD2;GNG5

AGTR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGTR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of AGTR1A.

Agtrap; Ankrd1

  • Q&As
  • Reviews

Q&As (10)

Ask a question
How does AGTR1A influence vascular tone? 09/25/2020

AGTR1A activation leads to vasoconstriction by stimulating smooth muscle cell contraction, thereby affecting vascular tone and blood pressure.

How can protein-protein interactions involving AGTR1A be studied in the lab? 05/29/2020

Techniques such as co-immunoprecipitation (Co-IP) or proximity-based assays like the fluorescence resonance energy transfer (FRET) can be utilized to investigate protein-protein interactions involving AGTR1A.

Are there specific ligands or agonists for AGTR1A? 04/04/2020

Angiotensin II is the primary ligand for AGTR1A, but there are also selective agonists and antagonists that can modulate its activity for research and therapeutic purposes.

Can AGTR1A polymorphisms influence drug response? 02/05/2020

Genetic polymorphisms in AGTR1A have been associated with variable responses to ARBs and other antihypertensive medications, affecting treatment outcomes.

How can AGTR1A signaling pathways be investigated in the lab? 11/10/2019

Lab researchers can use techniques like phospho-specific antibodies, ELISA assays, or luciferase reporter assays to assess the activation and downstream signaling of AGTR1A pathways.

Can AGTR1A contribute to insulin resistance and metabolic disorders? 08/08/2019

AGTR1A signaling has been implicated in insulin resistance, glucose metabolism, and the development of metabolic disorders such as obesity and diabetes.

What signaling pathways are activated by AGTR1A? 03/17/2019

AGTR1A activates various signaling pathways, including phospholipase C (PLC), protein kinase C (PKC), mitogen-activated protein kinases (MAPKs), and intracellular calcium release.

What are the structural features of AGTR1A that allow ligand binding? 01/14/2019

AGTR1A has extracellular domains and specific amino acid residues within the transmembrane region that facilitate angiotensin II binding and receptor activation.

How is AGTR1A activated? 07/11/2018

AGTR1A is activated when angiotensin II binds to the receptor, leading to conformational changes that initiate intracellular signaling cascades.

What is the process for screening compounds targeting AGTR1A in the lab? 07/14/2010

High-throughput screening (HTS) methods, such as cell-based assays or binding assays using radiolabeled ligands, can be employed to identify and evaluate potential compounds targeting AGTR1A.

Customer Reviews (5)

Write a review
Reviews
07/22/2022

    The customer service was fantastic—helpful, friendly, and made the ordering process a breeze!

    09/18/2021

      Quick delivery and secure packaging ensured my recombinant proteins arrived in perfect condition.

      04/10/2021

        Super impressed with the reliable recombinant proteins I received at such a reasonable cost

        02/24/2021

          The stability of this protein is unparalleled. It remains intact and active even under challenging conditions, ensuring reliable and reproducible results.

          08/20/2020

            Couldn't be happier with the high-quality recombinant proteins I got at such an amazing price.

            Ask a Question for All AGTR1A Products

            Required fields are marked with *

            My Review for All AGTR1A Products

            Required fields are marked with *

            logo

            FOLLOW US

            Terms and Conditions        Privacy Policy

            Copyright © 2024 Creative BioMart. All Rights Reserved.

            Contact Us

            • /

            Stay Updated on the Latest Bioscience Trends