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ALPPL2

  • Official Full Name

    alkaline phosphatase, placental-like 2

  • Overview

    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
  • Synonyms

    ALPPL2; alkaline phosphatase, placental-like 2; alkaline phosphatase, placental-like; ALP-1; Nagao isozyme; germ cell alkaline phosphatase; alkaline phosphatase Nagao isozyme; placental-like alkaline phosphatase; testicular and thymus alkaline phosphatase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ALPPL2-496H Recombinant Human ALPPL2 Protein, GST-tagged Wheat Germ GST
Human ALPPL2-3272H Recombinant Human ALPPL2, His-tagged E.coli His 532
Human ALPPL2-65HCL Recombinant Human ALPPL2 cell lysate N/A
Human ALPPL2-1488HF Recombinant Full Length Human ALPPL2 Protein, GST-tagged In Vitro Cell Free System GST 532 amino acids
Human ALPPL2-2862H Active Recombinant Human ALPPL2 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ile 20-Asp 503
Human ALPPL2-1993H Recombinant Human ALPPL2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse ALPPL2-1576M Recombinant Mouse ALPPL2 protein, His-tagged HEK293 His Val 19 - Ser 502
Mouse ALPPL2-490M Recombinant Mouse ALPPL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Alppl2-126M Recombinant Mouse Alppl2 Protein, His&GST-tagged E.coli N-His&GST Val19-Ser502
Mouse ALPPL2-490M-B Recombinant Mouse ALPPL2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ALPPL2 involved in several pathways and played different roles in them. We selected most pathways ALPPL2 participated on our site, such as Folate biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALPPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Folate biosynthesisALP3;QDPRB2;MOCS1;MOCS2;GCH1;FPGS;QDPRA;ALPPL2;GGH
Metabolic pathwaysSC4MOL;B4GALT4;FUT7;GALNT10;ACMSD;G6PC2;ETNK2;HPD;RDH8B

ALPPL2 has several biochemical functions, for example, alkaline phosphatase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALPPL2 itself. We selected most functions ALPPL2 had, and list some proteins which have the same functions with ALPPL2. You can find most of the proteins on our site.

Function Related Protein
alkaline phosphatase activityALPP;ALPPL2;ALPL;ALPI;ALPI.1;ALP3
metal ion bindingZNF771;OLA1;ZNF473;ZFP553;CBFA2T3;SP6;MCM2;NEK11;ATP13A3

ALPPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALPPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALPPL2.

Erh; Cep76

  • Q&As
  • Reviews

Q&As (10)

Ask a question
How can ALPPL2 activity and function be manipulated to modulate cellular processes and disease outcomes? 10/27/2022

Manipulating ALPPL2 activity and function holds promise for modulating cellular processes and disease outcomes, potentially offering new therapeutic avenues for metabolic disorders, liver diseases, and lipid-related conditions.

How does ALPPL2 dysregulation or deficiency contribute to the pathogenesis of diseases and disorders? 01/16/2022

Dysregulation or deficiency of ALPPL2 has been associated with metabolic disorders, liver diseases, and dyslipidemia, highlighting its contribution to the pathogenesis of these conditions.

Can ALPPL2 serve as a diagnostic biomarker or therapeutic target for specific diseases? 06/19/2021

ALPPL2 may serve as a potential diagnostic biomarker for specific diseases, providing insights into disease progression and therapeutic response, and it could be explored as a therapeutic target for developing interventions in certain pathological contexts.

What are the physiological functions and molecular interactions of ALPPL2 in cellular processes? 01/19/2021

ALPPL2 participates in cellular processes such as lipid metabolism, cell signaling, and membrane dynamics, and it interacts with other proteins and molecules involved in these processes.

How does ALPPL2 expression and activity change in response to physiological and pathological stimuli? 07/23/2020

ALPPL2 expression and activity are influenced by various physiological and pathological stimuli, including hormonal regulation, nutrient availability, and disease conditions.

What is the tissue-specific expression pattern of ALPPL2 and its cellular localization? 12/29/2019

ALPPL2 exhibits a specific expression pattern, with higher levels in certain tissues such as the liver, kidney, and intestine, and it is primarily localized to the plasma membrane or specific subcellular compartments.

What are the downstream signaling pathways and molecular targets regulated by ALPPL2 in cellular processes? 11/13/2019

ALPPL2 regulates downstream signaling pathways and molecular targets involved in lipid metabolism, cell proliferation, and cell survival, influencing cellular processes such as lipid signaling, membrane trafficking, and cell growth.

How does ALPPL2 contribute to the metabolism and turnover of its substrates in different cellular contexts? 02/13/2019

ALPPL2 is involved in the metabolism and turnover of its substrates, including lipid molecules and membrane components, playing important roles in cellular lipid homeostasis and membrane remodeling.

What are the upstream regulators and signaling pathways that control ALPPL2 expression and function? 06/01/2018

ALPPL2 expression is controlled by transcriptional regulators, signaling pathways, and epigenetic modifications that respond to specific cellular signals and environmental cues.

Can ALPPL2 be modulated by specific factors or inhibitors, and how does this affect its enzymatic activity and cellular functions? 02/11/2018

ALPPL2 activity can be modulated by specific factors, such as hormones or lipid-binding proteins, and inhibitors that target its catalytic site or affect its membrane association, leading to altered enzymatic activity and cellular functions.

Customer Reviews (3)

Write a review
Reviews
03/16/2022

    Versatile applications in multiple assay formats.

    02/07/2022

      Easy-to-use assay kit with clear protocols.

      01/25/2017

        Fast and efficient protein purification.

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