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ALS2CR8

  • Official Full Name

    amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8

  • Overview

    Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) is a protein that in humans is encoded by the ALS2CR8 gene.
  • Synonyms

    ALS2CR8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; calcium response factor; CaRF; FLJ21579; NYD SP24; calcium-response factor; testis development;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ALS2CR8-9603H Recombinant Human ALS2CR8, GST-tagged E.coli GST 1-311a.a.
Human ALS2CR8-509H Recombinant Human ALS2CR8 protein, GST-tagged Wheat Germ GST
Human ALS2CR8-68HCL Recombinant Human ALS2CR8 cell lysate N/A
Human ALS2CR8-1303HF Recombinant Full Length Human ALS2CR8 Protein, GST-tagged In Vitro Cell Free System GST 718 amino acids
Rat ALS2CR8-644R Recombinant Rat ALS2CR8 Protein Mammalian Cell His
Rat ALS2CR8-300R Recombinant Rat ALS2CR8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ALS2CR8-300R-B Recombinant Rat ALS2CR8 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ALS2CR8 Related Research Area

ALS2CR8 involved in several pathways and played different roles in them. We selected most pathways ALS2CR8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALS2CR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ALS2CR8 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALS2CR8 itself. We selected most functions ALS2CR8 had, and list some proteins which have the same functions with ALS2CR8. You can find most of the proteins on our site.

Function Related Protein
DNA bindingOTPB;DNAJB6;ONECUTL;EOMESB;DRL;ZZZ3;NEUROD6B;SCMH1;KRBA2
RNA polymerase II core promoter proximal region sequence-specific DNA bindingMED1;ZNF92;T;ZFP639;HNRNPC;SIX2;FOSL1;JUNB;MZF1
transcription factor activity, sequence-specific DNA bindingZNF19;ESR2;E2F2;ZFP583;FOXB1B;WT1A;HOXB7;KCNA3;CBL
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingKLF13;HOXA5;FOXD1;GLIS2;ARNT2;HEYL;GRHL1;SOX11;BCL11B

ALS2CR8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALS2CR8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALS2CR8.

saicar; PKM; purCD; LMO3

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Can the enzymatic activities of ALS2CR8 be characterized, and what are its potential substrates or targets? 02/22/2022

The enzymatic activities of ALS2CR8 are not well-characterized, and further studies are needed to identify its potential substrates or targets.

Are there any specific post-translational modifications that regulate ALS2CR8's activity or localization? How do these modifications impact its cellular functions? 12/01/2021

ALS2CR8 undergoes specific post-translational modifications, including phosphorylation or ubiquitination, that regulate its activity, stability, or subcellular localization.

Does ALS2CR8 play a role in synaptic function, neuronal connectivity, or plasticity? How does it affect these processes? 01/01/2021

ALS2CR8 plays a role in synaptic function, affecting processes such as neurotransmitter release, postsynaptic receptor trafficking, or synaptic vesicle dynamics.

Can therapeutic interventions targeting ALS2CR8 or its associated pathways offer potential strategies for treating neurological disorders or related conditions? 11/30/2020

Targeting ALS2CR8 or its associated pathways may hold therapeutic potential for treating neurological disorders, aiming to modulate synaptic function, promote neuronal survival, or enhance neuronal connectivity.

Is ALS2CR8 involved in intracellular signaling pathways or regulation of gene expression? If so, what are the downstream targets or effectors? 01/05/2020

ALS2CR8 is implicated in intracellular signaling pathways, such as those involved in neuronal survival, synaptic plasticity, or gene expression regulation.

How does ALS2CR8 expression change during neuronal development or in response to neuronal activity? Are there any factors or conditions that regulate its expression levels? 12/08/2019

ALS2CR8 expression is dynamically regulated during neuronal development and can be influenced by factors such as neuronal activity, neurotrophic factors, or signaling molecules.

How does ALS2CR8 contribute to neuronal development and function, and what are the underlying molecular mechanisms? 07/26/2019

ALS2CR8 is crucial for neuronal development and function, potentially influencing processes such as neurite outgrowth, synaptogenesis, or synaptic transmission through various molecular mechanisms.

Can the interactions of ALS2CR8 with other proteins or molecular complexes be identified and characterized? 01/27/2019

ALS2CR8 interacts with specific proteins or molecular complexes involved in neuronal signaling, cytoskeletal organization, or intracellular transport, which contribute to its cellular functions.

What is the cellular localization of ALS2CR8, and does it exhibit any specific associations with cellular compartments or organelles? 09/28/2017

ALS2CR8 is primarily localized to the cytoplasm, with potential associations with specific cellular compartments involved in neuronal function.

What are the functional domains or motifs present in ALS2CR8, and how do they contribute to its cellular functions? 09/04/2017

ALS2CR8 contains functional domains and motifs, such as protein-protein interaction domains or enzymatic domains, that play a role in its molecular functions.

Customer Reviews (3)

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Reviews
10/25/2022

    Compatible with automated liquid handling systems.

    08/14/2021

      Accurate assessment of protein expression changes.

      03/06/2017

        Low interference from endogenous proteins in samples.

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