AMIGO3
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Official Full Name
adhesion molecule with Ig-like domain 3
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Synonyms
AMIGO3; adhesion molecule with Ig-like domain 3; amphoterin-induced protein 3; amphoterin induced gene and open reading frame 3; Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene and ORF 3; Amphoterin induced protein 3 precursor; alivin-3; amphoterin-induced gene and ORF 3; AMIGO-3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- N/A
- AMIGO3 Related Articles
AMIGO3 involved in several pathways and played different roles in them. We selected most pathways AMIGO3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMIGO3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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AMIGO3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AMIGO3 itself. We selected most functions AMIGO3 had, and list some proteins which have the same functions with AMIGO3. You can find most of the proteins on our site.
| Function | Related Protein |
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AMIGO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMIGO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMIGO3.
- Q&As
- Reviews
Q&As (10)
Ask a questionAMIGO3 exhibits a unique tissue-specific expression pattern, with prominent expression in the central nervous system, particularly in regions involved in neuronal development and synaptic transmission, and lower expression in other organs.
Modulation of AMIGO3 expression or activity has the potential to influence neuronal plasticity and regeneration, promoting axonal growth and functional recovery in the context of injury or neurodegenerative conditions.
AMIGO3 may play a role in the formation and maintenance of myelin sheaths in the peripheral nervous system, contributing to proper nerve conduction and insulation of axons.
The regulation of AMIGO3 expression during brain development and in response to environmental stimuli involves complex molecular mechanisms, including transcriptional regulation, epigenetic modifications, and signaling pathways that respond to cues from the local microenvironment.
Different isoforms of AMIGO3 may have distinct functions, potentially influencing cellular processes such as neurite outgrowth, synaptogenesis, and cell adhesion in a context-dependent manner.
Targeting AMIGO3 expression or activity may hold promise as a therapeutic strategy for neurological conditions or neurodegenerative diseases, and further research is needed to understand its precise role and potential therapeutic implications.
Knockout or overexpression studies of AMIGO3 have revealed its critical role in neuronal connectivity and synaptic function, affecting processes such as dendritic arborization, synapse formation, and neurotransmitter release.
AMIGO3 interacts with specific cell adhesion molecules and signaling receptors, including members of the immunoglobulin superfamily and receptor tyrosine kinases, activating downstream signaling pathways involved in axonal guidance, cytoskeletal remodeling, and synaptic plasticity.
AMIGO3 plays a crucial role in neural development and axonal outgrowth, promoting the extension and guidance of growing axons during neuronal circuit formation.
Genetic variations in the AMIGO3 gene have been associated with neurological disorders, cognitive traits, and susceptibility to certain psychiatric conditions, suggesting a role in disease susceptibility and cognitive function.
Customer Reviews (3)
Write a reviewConsistent and reliable results across different experimental conditions.
High-resolution imaging for detailed protein localization.
Precise measurement of protein activity and function.
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