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Amy1

  • Official Full Name

    amylase 1, salivary

  • Synonyms

    alpha-amylase 1; alpha amylase 1; salivary and hepatic alpha-amylase; 1,4-alpha-D-glucan glucanohydrolase 1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse Amy1-3341M Recombinant Mouse Amy1, His-tagged E.Coli or Yeast His 511
Mouse AMY1-1612M Recombinant Mouse AMY1 Protein Mammalian Cell His
Mouse Amy1-7028M Recombinant Mouse Amy1 protein, His-tagged E.coli His Gln16~Ile511 (Accession # P00687)
Mouse AMY1-514M-B Recombinant Mouse AMY1 Protein Pre-coupled Magnetic Beads HEK293
Mouse AMY1-514M Recombinant Mouse AMY1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Amy1 Related Articles

Amy1 involved in several pathways and played different roles in them. We selected most pathways Amy1 participated on our site, such as Starch and sucrose metabolism, Metabolic pathways, Carbohydrate digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Amy1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Starch and sucrose metabolismUGT1AB;HKDC1;UGP2B;ENPP3;PYGMA;GBA3;UGT1A1;UGT1A3;GYS2
Metabolic pathwaysATP6V1B1;ACACB;POLR2J2;GGT5;CDS1;PLCB2;NT5C1A;GNE;CD38
Carbohydrate digestion and absorptionHKDC1;SLC2A5;AMY2A;ATP1A3;PIK3CB;G6PC3;PLCB2;TAS1R2;PIK3R2

Amy1 has several biochemical functions, for example, alpha-amylase activity, amylase activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Amy1 itself. We selected most functions Amy1 had, and list some proteins which have the same functions with Amy1. You can find most of the proteins on our site.

Function Related Protein
alpha-amylase activityAMY1B;AMY2A;AMY2A3;AMY2A2;AMY2A4;AMY1A;AMY2B;AMY2A5;Amy1
amylase activityAmy1;MAN1A;EDEM1;AMY2A5
calcium ion bindingPCDH2G17;DSG2.1;ATP2A2;SYT4;SPARC;SYT15;CABP2;PCDH2AB2;PROCA
catalytic activitySLC3A2;ALP3;AGXT2;GNSB;PCYT1AB;UQCRC2B;DIP2C;APOBEC2A;SYN1
cation bindingPPM1NB;PPM1LA;GBE1;Amy1;SLC3A1;PPM1DB;PPM1DA;PPM1E;PPM1LB
chloride ion bindingCTSC;NLGN4X;AMY2A;Amy1;ACE;SLC22A6
hydrolase activityPPP1CAB;RAG1;CES1C;REXO1;ATP1A1B;PPM1H;HDAC7;PNPLA7;BPGM
hydrolase activity, acting on glycosyl bondsChil3;MAN1A;GALCA;SPACA5;UNGA;HPSE2;MACROD2;SMPDL3A;LYZ2
metal ion bindingSP5L;PARP12;HRG;CYP2D26;ATMIN;GNA13;ZC3H11A;SRSF7A;GM3258

Amy1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Amy1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Amy1.

glycogen; Hbb-b2; Fth1; Ctsb; Cat; Ppib; Ftl1; Ppp1ca; Cps1; Stbd1; Agl; Pygb; Gys2; Pygl; Gyg1; Pygm; Ctsz

Pooja, S; Pushpanathan, M; et al. Identification of Periplasmic alpha-Amlyase from Cow Dung Metagenome by Product Induced Gene Expression Profiling (Pigex). INDIAN JOURNAL OF MICROBIOLOGY 55:57-65(2015).
Perry, GH; Kistler, L; et al. Insights into hominin phenotypic and dietary evolution from ancient DNA sequence data. JOURNAL OF HUMAN EVOLUTION 79:55-63(2015).
  • Q&As
  • Reviews

Q&As (9)

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Can changes in AMY1 gene expression be influenced by environmental factors? 05/30/2022

Yes, it is believed that environmental factors, such as diet and lifestyle, can influence the expression of the AMY1 gene. For example, studies have demonstrated that increased consumption of starch in the diet can lead to an upregulation of AMY1 gene expression, resulting in higher levels of salivary amylase. Additionally, certain medications and diseases that affect the salivary glands or overall metabolism can potentially impact AMY1 gene expression and subsequent amylase levels.

How do variations in the AMY1 gene affect starch digestion and metabolism? 02/22/2022

Variations in the AMY1 gene, which codes for the AMY1 protein, can impact starch digestion and metabolism. In individuals with a higher number of AMY1 gene copies, there is increased production of salivary alpha-amylase, leading to higher levels of the enzyme in the saliva. This increased enzyme activity can facilitate better digestion of starches, resulting in more efficient breakdown of complex carbohydrates into simpler sugars.

Can AMY1 protein levels in saliva be measured? 06/01/2021

Yes, the levels of AMY1 protein in saliva can be measured through biochemical assays. These assays typically involve detecting the enzymatic activity of salivary amylase on a starch substrate. By quantifying the breaking down of starch into smaller sugars, the level of AMY1 protein activity in one's saliva can be estimated. Various commercial kits and laboratory methods are available for such measurements.

Are there any therapeutic implications of AMY1 protein research? 03/11/2020

The understanding of AMY1 protein research can potentially be utilized in therapeutic interventions for individuals with certain metabolic disorders or conditions characterized by impaired carbohydrate digestion.

Is there a correlation between AMY1 gene variations and different populations or ethnic groups? 02/05/2020

Yes, there is evidence to suggest that the number of AMY1 gene copies can vary among different populations and ethnic groups. Studies have found that populations with a long history of consuming starch-rich diets, such as those in East Asia and parts of Africa, tend to have a higher number of AMY1 gene copies compared to populations with traditional low-starch diets, such as some indigenous groups in the Americas. This variation may reflect adaptations to local dietary practices over time.

Are there any potential applications or implications of AMY1 protein research? 02/11/2019

Research on the AMY1 protein and its genetic variations can have several applications and implications. It can provide insights into individual dietary needs by understanding how variations in the AMY1 gene affect starch digestion and metabolism. This knowledge may be useful in personalized nutrition recommendations, helping individuals optimize their carbohydrate intake for better health outcomes.

Are there any health implications associated with variations in the AMY1 gene? 10/25/2017

Variations in the AMY1 gene have been studied in the context of nutrition, obesity, and metabolic health. Some research suggests that individuals with a higher number of AMY1 gene copies may have a better ability to handle starches in their diet, which could potentially contribute to better blood sugar control and reduced risk of obesity and related metabolic disorders.

Are there any variations in the AMY1 gene that impact its function? 04/08/2017

Yes, there are genetic variations in the AMY1 gene that have been found to influence the production and activity of the AMY1 protein. These variations affect the number of copies of the AMY1 gene an individual has. Some individuals have a higher number of AMY1 gene copies, leading to increased AMY1 protein production and higher salivary amylase levels in their saliva. On the other hand, some individuals have fewer gene copies, resulting in lower salivary amylase levels. This genetic variation is thought to contribute to individual differences in starch digestion and metabolism.

Where is the AMY1 protein produced? 04/03/2017

The production of the AMY1 protein primarily occurs in the salivary glands, specifically in the parotid glands, which are the largest of the salivary glands. Salivary alpha-amylase is produced and secreted into the saliva, where it becomes active in starch digestion.

Customer Reviews (5)

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Reviews
09/24/2022

    This flexibility allows for tailored approaches and provides researchers with more options to study specific aspects of AMY1 biology or its interactions with other molecules.

    10/27/2021

      Manufacturers can provide comprehensive product information, including data on the functionality, stability, and handling of AMY1 protein.

      03/04/2021

        Manufacturers can ensure high-quality production of AMTN protein, maintaining its purity and integrity.

        12/26/2017

          Reputable manufacturers often provide technical support to researchers using AMY1 protein.

          02/02/2016

            This guarantees the reliability and reproducibility of research findings and eliminates potential issues arising from impurities or contamination.

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