anapc7
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  • Official Full Name
  • anaphase promoting complex subunit 7
  • Background
  • This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
  • Synonyms
  • ANAPC7; anaphase promoting complex subunit 7; APC7; anaphase-promoting complex subunit 7; cyclosome subunit 7;
Cat.#:ANAPC7-2084HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANAPC7 Protein, MYC/DDK-tagged
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Cat.#:ANAPC7-547HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANAPC7 protein, GST-tagged
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Cat.#:ANAPC7-9640HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANAPC7, GST-tagged
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Cat.#:ANAPC7-1626MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ANAPC7 Protein
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Cat.#:ANAPC7-6323ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ANAPC7
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Involved Pathway

ANAPC7 involved in several pathways and played different roles in them. We selected most pathways ANAPC7 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANAPC7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
HTATIP; BUB1B; MPEG1; HDAC5; MCM10; MAPRE1B; SETA; SPDL1; LIN54; CDKN1BA
Oocyte meiosis
ADCY1B; CALM2B; ANAPC4; RPS6KA6; CCNB2; INS1; PRKACA; YWHAQA; RPS6KA2; CALML5
Ubiquitin mediated proteolysis
ANAPC13; RHOBTB2; UBE2H; RBX1; PPIL2; ANAPC4; ERCC8; UBE2NA; PIAS4A; XIAP
Progesterone-mediated oocyte maturation
PRKACBB; CCNA1; INS; PDE3B; PIK3CD; CPEB2; RAF1B; CPEB4; ANAPC4; AKT3A
HTLV-I infection
ATF3; POLD1; POLE4; H2-AA; RELA; CANX; PIK3CG; WNT10B; BUB1B; SLC25A4

Protein Function

ANAPC7 has several biochemical functions, for example, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANAPC7 itself. We selected most functions ANAPC7 had, and list some proteins which have the same functions with ANAPC7. You can find most of the proteins on our site.
Function
Related Protein
Function protein phosphatase binding
Related Protein CDH5; KAT2A; ANAPC4; TRAF3; TRP53; FGF19; CSK; STAT6; TRAF2; PIK3R1

Interacting Protein

ANAPC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANAPC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANAPC7.
BUB1B; Cdc23; Cdc16; Cdc26; Anapc16; Cdc20; CDC23; Cdk1; CDC16

ANAPC7 Related Articles

Ho, AW; Garg, AV; et al. The Anaphase-Promoting Complex Protein 5 (AnapC5) Associates with A20 and Inhibits IL-17-Mediated Signal Transduction. PLOS ONE 8:-(2013).