ANGEL2
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Official Full Name
angel homolog 2 (Drosophila)
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Synonyms
ANGEL2; angel homolog 2 (Drosophila); protein angel homolog 2; FLJ12793; KIAA0759L; ANGE2_HUMAN; Angel homolog 2; LOC90806 protein; OTTHUMP00000035020; OTTHUMP00000035021;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ANGEL2-549H | Recombinant Human ANGEL2 protein, GST-tagged | Wheat Germ | GST | ||
Human | ANGEL2-21HCL | Recombinant Human ANGEL2 lysate | HEK293 | N/A | ||
Human | ANGEL2-2081H | Recombinant Human ANGEL2 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | ANGEL2-4451H | Recombinant Human ANGEL2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | ANGEL2-1498HF | Recombinant Full Length Human ANGEL2 Protein, GST-tagged | In Vitro Cell Free System | GST | 286 amino acids | |
Mouse | ANGEL2-1633M | Recombinant Mouse ANGEL2 Protein | Mammalian Cell | His | ||
Mouse | Angel2-1625M | Recombinant Mouse Angel2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | ANGEL2-528M | Recombinant Mouse ANGEL2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ANGEL2-528M-B | Recombinant Mouse ANGEL2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ANGEL2-3188Z | Recombinant Zebrafish ANGEL2 | Mammalian Cell | His | ||
Chicken | ANGEL2-2727C | Recombinant Chicken ANGEL2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ANGEL2 involved in several pathways and played different roles in them. We selected most pathways ANGEL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGEL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ANGEL2 has several biochemical functions, for example, mRNA 3-UTR binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGEL2 itself. We selected most functions ANGEL2 had, and list some proteins which have the same functions with ANGEL2. You can find most of the proteins on our site.
Function | Related Protein |
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mRNA 3-UTR binding | CRYZ;SECISBP2;LARP1;ELAVL1;IGF2BP3;ELAVL4;CSDA;CARHSP1;CPEB1 |
ANGEL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANGEL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGEL2.
LRP8
- Q&As
- Reviews
Q&As (12)
Ask a questionCurrently, there are no known specific disorders or diseases directly associated with ANGEL2 mutations or dysregulation. However, some studies have indicated potential links between ANGEL2 and certain conditions, such as autism spectrum disorder and intellectual disability. Further research is needed to establish a definitive connection.
Research exploring protein-protein interactions and pathways involving ANGEL2 is limited. However, some studies have suggested potential interactions with proteins involved in protein synthesis, RNA processing, and cellular growth. Future studies may provide more insights into the specific molecular interactions and pathways associated with ANGEL2.
There is limited information available regarding the specific cellular signaling pathways in which ANGEL2 is involved. Further research is needed to determine its interactions with signaling molecules and pathways.
The exact functions of ANGEL2 are not well understood. However, some studies suggest that ANGEL2 may play a role in neurodevelopment and neuronal signaling. It has also been implicated in the regulation of neuronal migration, as well as in synaptic function and plasticity. Further research is needed to determine its precise functions and molecular mechanisms.
ANGEL2 is conserved in various species, including mammals, suggesting its importance in biological processes. However, the degree of conservation and functional relevance across species are areas that require further investigation.
Research on ANGEL2 is ongoing, particularly in the context of neurodevelopmental disorders such as autism spectrum disorder and intellectual disability. Scientists are exploring its cellular function, interactions, and potential contributions to diseases. It is an area of active investigation, and new findings may emerge in the future.
Due to the limited understanding of ANGEL2's function and involvement in diseases, there are currently no specific therapies targeting this protein. Further research is required to elucidate its role in cellular processes and potential therapeutic avenues.
Given the limited understanding of ANGEL2 and its functions, it is currently unclear whether it can be targeted for therapeutic purposes. However, further research on ANGEL2's molecular mechanisms and its association with specific diseases may provide insights into potential therapeutic strategies in the future.
At present, there are no known specific animal models specifically targeting ANGEL2. Generating animal models with ANGEL2 genetic modifications might help in understanding its function in vivo and the associated disease implications.
The ANGEL2 gene does have genetic variants and mutations, but their specific implications and associations with diseases are not well-defined. More research is needed to understand the potential impact of these genetic changes on ANGEL2 function and their involvement in diseases.
ANGEL2 has been associated with neurodevelopmental disorders such as autism spectrum disorder (ASD) and intellectual disability. Some genetic studies have identified rare variants or mutations in ANGEL2 in individuals with these disorders. However, the exact role of ANGEL2 in disease development and the underlying mechanisms remain to be fully elucidated.
There is limited information on the interactors or binding partners of ANGEL2. However, some studies suggest that ANGEL2 may interact with proteins involved in neuronal development and synaptic function, such as NMDA receptors and GABA receptors. Further research is needed to characterize its binding partners and understand the functional implications of these interactions.
Customer Reviews (4)
Write a reviewANGEL2 protein's utility in protein electron microscopy structure analysis is commendable.
ANGEL2 protein is highly recommended for various research applications, including ELISA and protein electron microscopy structure analysis.
It enables researchers to delve deeper into the intricacies of protein behavior and aids in advancing our knowledge in various fields, such as molecular biology, biochemistry, and structural biology.
Structural biology researchers can leverage its properties to better understand the three-dimensional architecture and conformational changes of proteins, gaining valuable insights into their function and interactions.
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