ano10
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  • Official Full Name
  • anoctamin 10
  • Background
  • The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels. Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10. Several transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ANO10; anoctamin 10; TMEM16K, transmembrane protein 16K; anoctamin-10; FLJ10375; MGC47890; SCAR10; Hypothetical protein LOC55129; TMEM 16K; Transmembrane protein 16K; OTTHUMP00000164038; OTTHUMP00000164039; OTTHUMP00000209958; OTTHUMP00000209959; OTTHUMP00000209960; TMEM16K
Cat.#:ANO10-4216HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANO10 Protein, GST-tagged
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Cat.#:ANO10-1697MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ANO10 Protein
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Involved Pathway

ANO10 involved in several pathways and played different roles in them. We selected most pathways ANO10 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANO10 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ion channel transport
TRPM4A; SLC9A10; ASIC1A; TRPC5; CLIC2; TSC22D3; MCOLN3; TRDN; SGK2; SRI
Stimuli-sensing channels
OSTM1; BEST4; CLCNK; CLCN4-2; ANO7; ANO10; TRPM6; CLCA1; TRPC4A; CLCN1A
Transmembrane transport of small molecules
ANO10A; MRS2; SLC38A3; UNC79; GSDMA2; MCOLN2; CLCNK; SLC1A2B; SLC6A15; SLC34A3

Protein Function

ANO10 has several biochemical functions, for example, calcium activated cation channel activity, NOT intracellular calcium activated chloride channel activity, NOT phospholipid scramblase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANO10 itself. We selected most functions ANO10 had, and list some proteins which have the same functions with ANO10. You can find most of the proteins on our site.
Function
Related Protein
Function calcium activated cation channel activity
Related Protein TRPM5; PKD2L1; TRPM4; TMEM63C; TRPM4A; CALHM1; TRPM4C; CATSPER2; CATSPER1; ANO10
Function NOT intracellular calcium activated chloride channel activity
Related Protein ANO7; ANO9; ANO8; ANO5; Ano3; ANO10; ANO6
Function NOT phospholipid scramblase activity
Related Protein ANO2; ANO10; ANO5

Interacting Protein

ANO10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANO10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANO10.
Tmem173