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ANO7

  • Official Full Name

    anoctamin 7

  • Overview

    This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms

    ANO7; anoctamin 7; PCANAP5, TMEM16G, transmembrane protein 16G; anoctamin-7; IPCA 5; NGEP; PCANAP5L; transmembrane protein 16G; prostate cancer associated protein 5; Dresden-transmembrane protein of the prostate; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TM;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ANO7-8844HCL Recombinant Human ANO7 293 Cell Lysate HEK293 N/A
Mouse ANO7-1702M Recombinant Mouse ANO7 Protein Mammalian Cell His
Mouse ANO7-571M-B Recombinant Mouse ANO7 Protein Pre-coupled Magnetic Beads HEK293
Mouse ANO7-571M Recombinant Mouse ANO7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ANO7-682R Recombinant Rat ANO7 Protein Mammalian Cell His
Rat ANO7-338R Recombinant Rat ANO7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ANO7-338R-B Recombinant Rat ANO7 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ANO7 Related Articles
  • ANO7 Related Research Area

ANO7 involved in several pathways and played different roles in them. We selected most pathways ANO7 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANO7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ion channel transportTRPC4B;BSND;CLCN5;TCIRG1;ATP1A1A.2;NHEDC1;ATP1A1A.5;TRPM4A;GSDMA2
Stimuli-sensing channelsANO10;TRPC4;TRPC5;ANO7;ANO6;TTYH3;SLC17A3;TRPC4AP;ASIC1A
Transmembrane transport of small moleculesANO6;SLC31A1;CLCN6;SLC15A4;SLC6A19A;MAGT1;SLC39A6;SLC35B4;UNC79

ANO7 has several biochemical functions, for example, intracellular calcium activated chloride channel activity, NOT intracellular calcium activated chloride channel activity, phospholipid scramblase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANO7 itself. We selected most functions ANO7 had, and list some proteins which have the same functions with ANO7. You can find most of the proteins on our site.

Function Related Protein
intracellular calcium activated chloride channel activityCLCA2;ANO9;CLCA4;ANO6;ANO7;NMUR2;ANO8;ANO4;CLCA1
NOT intracellular calcium activated chloride channel activityAno3;ANO9;ANO7;ANO10;ANO8;ANO5;ANO6
phospholipid scramblase activityAno3;PLSCR4;PLSCR2;PLSCR1;ANO7;PLSCR3A;ANO4;ANO9;PLSCR3
protein dimerization activityLDB1A;MNTB;MNT;MESPAB;MITFA;MYCH;HER3;PIP;MYO5A

ANO7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANO7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANO7.

Ousingsawat, J; Wanitchakool, P; et al. Anoctamin 6 mediates effects essential for innate immunity downstream of P2X(7) receptors in macrophages. NATURE COMMUNICATIONS 6:-(2015).
Mazzone, A; Gibbons, SJ; et al. Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6). FASEB JOURNAL 29:152-163(2015).
  • Q&As
  • Reviews

Q&As (5)

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Is there any known interaction partner or regulatory mechanism of ANO7 protein? 03/03/2023

The specific interaction partners and regulatory mechanisms of ANO7 protein are not yet well characterized. Further research is needed to understand its interaction network and functional regulation.

Are there any known substrates or ligands for ANO7 protein? 02/14/2020

The substrates and ligands for ANO7 protein are not yet well defined. Further studies are needed to determine its specific binding partners and functional interactions.

Is there any known ANO7 protein homologue in other species? 05/01/2017

Yes, ANO7 protein has homologues in other species. In humans, it shares sequence homology with ANO1-6 proteins, and similar proteins are found in other vertebrate species as well.

What are the potential roles of ANO7 protein in disease? 04/04/2017

ANO7 protein has been implicated in several diseases. Mutations in the ANO7 gene have been associated with the development of prostate cancer and neurodegenerative disorders like Parkinson's disease.

Where is ANO7 protein expressed? 06/15/2016

ANO7 protein is expressed in various tissues, including the brain, heart, skeletal muscle, and gastrointestinal system.

Customer Reviews (5)

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Reviews
05/30/2021

    ANO7 is known for its high purity and quality, ensuring accurate and reproducible results.

    03/28/2021

      With its well-characterized nature and availability in various formats, the ANO7 protein is an advantageous tool that aids researchers in achieving their scientific goals.

      02/09/2021

        The manufacturer also ensures that the ANO7 protein is well-characterized, with extensive documentation on its functional properties.

        05/22/2018

          One of the key advantages of working with the ANO7 protein is the comprehensive support provided by its manufacturer.

          07/12/2017

            Whether it's troubleshooting issues, optimizing experimental protocols, or providing detailed information about the protein, the manufacturer's support team is dedicated to helping researchers overcome any challenges they may encounter.

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