ANO8
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Official Full Name
anoctamin 8
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Synonyms
ANO8;anoctamin 8;29329;ENSG00000074855;TMEM16H;KIAA1623;19p13.11;anoctamin-8;anoctamin-8;transmembrane protein 16H;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ANO8-976H | Recombinant Human ANO8 | Mammalian Cell | His |
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| Human | ANO8-2478H | Recombinant Human ANO8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | ANO8-2478H-B | Recombinant Human ANO8 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | ANO8-1703M | Recombinant Mouse ANO8 Protein | Mammalian Cell | His |
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| Mouse | ANO8-572M | Recombinant Mouse ANO8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ANO8-572M-B | Recombinant Mouse ANO8 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
ANO8 involved in several pathways and played different roles in them. We selected most pathways ANO8 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANO8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ion channel transport | SLC9B2;ATP11C;ATP2B3A;CCC2;ANO5;UNC79;ANO10;WNK2;ATP1A1A.2 |
| Stimuli-sensing channels | TRPM4C;CLCNKA;CLCN4-2;TTYH1;SLC9A10;TTYH3;ANO10A;ANO5;BSND |
| Transmembrane transport of small molecules | ANKH;SLC29A2;ANO7;SLC38A3A;MCOLN3;SGK2;ATP13A;MIPB;SLC35A2 |
ANO8 has several biochemical functions, for example, NOT intracellular calcium activated chloride channel activity, intracellular calcium activated chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANO8 itself. We selected most functions ANO8 had, and list some proteins which have the same functions with ANO8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT intracellular calcium activated chloride channel activity | ANO6;ANO5;ANO9;ANO7;ANO8;ANO10;Ano3 |
| intracellular calcium activated chloride channel activity | CLCA4;CLCA2;NMUR2;ANO9;ANO6;ANO2;ANO7;ANO4;CLCA1 |
ANO8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANO8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANO8.
COQ9
- Q&As
- Reviews
Q&As (4)
Ask a questionANO8 protein is known to be involved in several biological processes. It has been implicated in calcium-activated chloride channel activity, which plays a role in chloride ion transport across cell membranes. ANO8 may also participate in phospholipid scrambling, a process in which lipids are redistributed between leaflets of the cell membrane.
Yes, there are several proteins known to interact with ANO8. For example, it has been shown to interact with the scaffolding protein caveolin-1, which is involved in cellular signaling and membrane organization. ANO8 has also been found to interact with transmembrane protein 16F (TMEM16F), another member of the Anoctamin family, forming heteromeric complexes that regulate chloride channel activity. Additionally, ANO8 may interact with other proteins involved in calcium signaling and lipid metabolism, although further research is needed to fully elucidate its protein-protein interactions.
Emerging evidence suggests that ANO8 protein may have implications in certain diseases. For example, ANO8 gene mutations have been associated with autosomal recessive spinocerebellar ataxia, which is a neurodegenerative disorder affecting coordination and movement. ANO8 expression has also been linked to cancer development and progression, including gastrointestinal stromal tumors and colorectal cancer. However, more research is needed to fully understand its involvement in these diseases.
The potential therapeutic targeting of ANO8 protein is an area of ongoing research. Given its involvement in various cellular processes and its association with certain diseases, ANO8 could serve as a target for drug development.
Customer Reviews (4)
Write a reviewThis flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.
the manufacturer's support team provides extensive technical assistance, helping researchers navigate any challenges they may face throughout their experiments.
the ANO8 protein is available in different formats, including recombinant and purified variants.
researchers using the ANO8 protein can benefit from its high purity and quality, ensuring reliable results.
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