APBA3
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Official Full Name
amyloid beta (A4) precursor protein-binding, family A, member 3
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Overview
binds the cytoplasmic tail of amyloid beta precursor protein APP; also binds presenilin 1 cytoplasmic tail -
Synonyms
APBA3; amyloid beta (A4) precursor protein-binding, family A, member 3; amyloid beta A4 precursor protein-binding family A member 3; mint3; X11 like 2; X11L2; mint-3; X11-like 2 protein; adapter protein X11gamma; neuron-specific X11L2 protein; neuronal mu;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- Myc|DDK
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | APBA3-7825H | Recombinant Human APBA3, His-tagged | E.coli | His |
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| Human | APBA3-2316H | Recombinant Human APBA3 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | APBA3-198H | Recombinant Human APBA3 Protein, His-tagged | E.coli | N-His | Asp23-Leu278 |
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| Mouse | Apba3-3436M | Recombinant Mouse Apba3, His-tagged | E.Coli or Yeast | His | 571 |
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| Mouse | Apba3-8067M | Recombinant Mouse Apba3 protein, His & T7-tagged | E.coli | His/T7 | Val261~Leu506 (Accession # O88888) |
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| Mouse | APBA3-1756M | Recombinant Mouse APBA3 Protein | Mammalian Cell | His |
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| Mouse | APBA3-614M | Recombinant Mouse APBA3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | APBA3-614M-B | Recombinant Mouse APBA3 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | APBA3-709R | Recombinant Rat APBA3 Protein | Mammalian Cell | His |
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| Rat | APBA3-365R | Recombinant Rat APBA3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | APBA3-365R-B | Recombinant Rat APBA3 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- APBA3 Related Articles
APBA3 involved in several pathways and played different roles in them. We selected most pathways APBA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APBA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
APBA3 has several biochemical functions, for example, beta-amyloid binding, enzyme binding, enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APBA3 itself. We selected most functions APBA3 had, and list some proteins which have the same functions with APBA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-amyloid binding | BACE1;APBB2;TM2D1;FBXO2;APBA2;IDE;APBB3;TSSK1B;CLSTN1 |
| enzyme binding | PIAS3;RCOR3;RCOR2;SLC12A3;TSPAN10;UGT1A6;BCHE;UGT1A9;CLSTN2 |
| enzyme inhibitor activity | SLN;APBA3;DGKZ;APOV1;TAE1;OAZ2A;OAZ1A;UGT1A7;PPP1R12A |
| protein binding | PPP3CC;SNRPN;FCRL2;PNMA2;CORO2B;MEF2A;LBR;INPP5D;AKAP8L |
APBA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APBA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of APBA3.
BCR; TBKBP1; TANK; Azi2; EGFR; CBR1
- Q&As
- Reviews
Q&As (10)
Ask a questionThe application prospects of APBA3 in neurodegenerative diseases are still uncertain, but its involvement in synaptic transmission and neurotransmitter regulation may have potential value in the treatment of such diseases.
Yes, the APBA3 protein can interact with other proteins, including those involved in synaptic transmission and neurotransmitter regulation.
Recombinant APBA3 protein has potential clinical applications, including neurodegenerative diseases, cognitive disorders and cancer treatment.
The side effects of APBA3 are currently unclear and require further clinical studies and validation.
APBA3 protein is a multi-domain protein whose main function is to participate in the regulation of signal transduction and synaptic transmission of neurotransmitters.
Recombinant APBA3 may have a positive effect on cognitive function, improving cognition by regulating synaptic transmission and neurotransmitter balance.
At present, the clinical trial of APBA3 is under way, and the specific progress needs to consult the relevant clinical research institutions.
The mechanism of action of APBA3 in cancer therapy is not clear, but some studies suggest that it may be involved in the regulation of signal transduction pathways, thereby inhibiting tumor growth and metastasis.
Whether the recombinant APBA3 protein can be administered orally to patients still needs further study. At present, it is mainly administered by injection.
Recombinant APBA3 proteins are usually synthesized in cells by genetic engineering techniques and then purified and purified, for example using affinity chromatography.
Customer Reviews (4)
Write a reviewThe short half-life and high clearance characteristics of APBA3 allow it to better interact with other drugs, so as to better play the effect of combination therapy.
Green production process of APBA3 realizes the efficient use of energy, reduces energy consumption, reduces carbon emissions, and is very friendly to the environment.
APBA3 is highly stable and reproducible, which brings great convenience to our experiments. The results of each experiment are very consistent, giving us more confidence in its quality and reliability.
Stability of APBA3 is very good, and the results remain consistent after repeated use, showing good product quality.
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