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APLP1

  • Official Full Name

    amyloid beta (A4) precursor-like protein 1

  • Overview

    Amyloid-like protein 1, also known as APLP1, is a protein that in humans is encoded by the APLP1 gene. APLP1 along with APLP2 are important modulators of glucose and insulin homeostasis.
  • Synonyms

    APLP1; amyloid beta (A4) precursor-like protein 1; amyloid-like protein 1; amyloid precursor like protein 1; amyloid like protein 1; APLP; APLP-1; amyloid precursor-like protein 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human APLP1-687H Recombinant Human APLP1 protein, GST-tagged Wheat Germ GST
Human APLP1-9745H Recombinant Human APLP1, GST-tagged E.coli GST 55-341a.a.
Human APLP1-26119TH Recombinant Human APLP1, His-tagged E.coli His
Human APLP1-350H Recombinant Human APLP1, His tagged Human Cell N/A
Human APLP1-1031HCL Recombinant Human APLP1 cell lysate Human Cell N/A
Human APLP1-63H Recombinant Human APLP1 Protein, His-tagged Human Cell His Gly42-Pro212
Human APLP1-394H Recombinant Human APLP1 Protein, His-tagged E.coli His Arg62~Phe202
Human APLP1-1102H Recombinant Human APLP1 protein(Met1-Glu580), His-tagged HEK293 C-His Met1-Glu580
Human APLP1-3718H Recombinant Human APLP1 protein, His-tagged E.coli His 55-341 aa
Mouse Aplp1-3443M Recombinant Mouse Aplp1, His-tagged E.Coli or Yeast His 654
Mouse APLP1-1776M Recombinant Mouse APLP1 Protein Mammalian Cell His
Mouse APLP1-623M Recombinant Mouse APLP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Aplp1-295M Recombinant Mouse Aplp1 Protein, His-tagged HEK293 His Met1-Glu584
Mouse APLP1-623M-B Recombinant Mouse APLP1 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL-35884HF Recombinant Full Length Human Amyloid-Like Protein 1(Aplp1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (39-650)
Mus musculus (Mouse) RFL-30829MF Recombinant Full Length Mouse Amyloid-Like Protein 1(Aplp1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (38-653)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • APLP1 Related Articles

APLP1 involved in several pathways and played different roles in them. We selected most pathways APLP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APLP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

APLP1 has several biochemical functions, for example, alpha-2A adrenergic receptor binding, alpha-2B adrenergic receptor binding, alpha-2C adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APLP1 itself. We selected most functions APLP1 had, and list some proteins which have the same functions with APLP1. You can find most of the proteins on our site.

Function Related Protein
alpha-2A adrenergic receptor bindingAPLP1;ADRBK1;UCHL1;ADRA2C;ADRB1
alpha-2B adrenergic receptor binding
alpha-2C adrenergic receptor bindingAPLP1;ADRA2A
heparin bindingFGF14;CXCL10;CHRD;CYR61L1;FGFBP1;LIPI;APOE;SELL;APLP1
identical protein bindingNLRC4;GSTM3;PKD2;SIAH1A;HAND2;SH3GL2;CCL3;CRYAB;AKT1
protein bindingCOMMD1;ASB2;ATMIN;RAB1A;DNA2;ARL16;CREB3;WDR25;ESR1
transition metal ion bindingAPP;APLP1;APPB;APLP2;APPA;HRSP12

APLP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APLP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of APLP1.

TK1; TSC22D1; APP; APLP2; ZNF24; CNTN5; CNTN4; MED12; CNTN3; Tom1; FOS

Shi, M; Movius, J; et al. Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation. MOLECULAR & CELLULAR PROTEOMICS 14:544-555(2015).
Sano, S; Tagami, S; et al. Absolute Quantitation of Low Abundance Plasma APL1 beta peptides at Sub-fmol/mL Level by SRM/MRM without Immunoaffinity Enrichment. JOURNAL OF PROTEOME RESEARCH 13:1012-1020(2014).
  • Q&As
  • Reviews

Q&As (20)

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Can recombinant APLP1 be used in the treatment of neurodegenerative diseases? 12/28/2022

APLP1 is considered as one of the therapeutic directions for neurodegenerative diseases, and related research and development is ongoing.

What is the relationship between APLP1 and the formation of neuronal axons? 12/13/2022

APLP1 is closely related to the formation of neuronal axons, which can regulate the formation and development of neuronal axons.

What role does APLP1 play in synaptic plasticity? 11/13/2022

APLP1 plays an important role in synaptic plasticity, regulating the formation and plasticity of synapses.

What is the relationship between APLP1 and Alzheimer's disease? 09/24/2022

Studies have shown that APLP1 is associated with Alzheimer's disease and may be one of the triggers of Alzheimer's disease.

What is the relationship between APLP1 and beta-amyloid protein? 07/24/2022

APLP1 is related to beta-amyloid protein, which is one of the main components of beta-amyloid substances.

What is the physiological function of APLP1 ? 06/22/2022

The physiological functions of APLP1 include cell signaling, neuronal development, neuronal protection, metabolic regulation and so on.

Is the genetic mutation of APLP1 associated with certain diseases? 06/19/2022

Mutations in the APLP1 are associated with a variety of diseases, including cancer and neurological disorders.

What is the relationship between APLP1 and synaptic repair? 01/23/2022

APLP1 is associated with the repair of neuronal synapses and can promote the reconstruction and repair of neuronal synapses.

Can APLP1 be used as a target for drug development? 01/20/2022

It can be used as a target for drug development, and drug studies targeting APLP1 are ongoing.

What kind of diseases can APLP1 be used to treat? 01/11/2022

APLP1 can be used in the treatment of neurodegenerative diseases, stroke, metabolic diseases and other aspects.

What is the role of APLP1 in cell signaling? 11/26/2021

APLP1 plays an important role in cell signaling and can participate in a series of biological processes such as cell proliferation, apoptosis and differentiation.

What is the relationship between APLP1 and neuron cell membrane? 10/10/2021

APLP1 can participate in the formation and stability of neuron cell membrane, and plays an important role in the development and maintenance of cell membrane.

In what fields does APLP1 have application prospects? 12/26/2020

APLP1 can be applied to neurodegenerative diseases, cancer, and metabolic diseases.

Does APLP1 affect cognition and learning ability? 11/24/2020

Some studies suggest that APLP1 may have an effect on memory and learning ability.

What is the relationship between APLP1 and cancer? 09/18/2020

APLP1 has been found to be associated with a variety of cancers, and it may serve as a cancer marker or therapeutic target.

What are the antioxidant properties of APLP1 ? 08/13/2020

APLP1 can play an antioxidant role by inhibiting the generation of free radicals and regulating the activity of antioxidant enzymes.

What is the role of APLP1 in inflammatory response? 03/24/2020

APLP1 plays an important biological role in inflammatory response, and studies have shown that it can be involved in regulating the body's immune response and cytokine play.

What are the preparation methods of APLP1 ? 01/07/2020

The preparation methods of APLP1 include genetic engineering technology, cell culture technology, etc.

What are the effects of APLP1 on adult nerve cells? 12/08/2019

Studies have shown that APLP1 can improve the living environment of adult nerve cells and protect nerve cells from damage.

What is the role of APLP1 in nerve cells? 05/21/2019

Studies have shown that APLP1 plays an important role in the development and protection of neurons and can prevent neuronal apoptosis.

Customer Reviews (4)

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Reviews
12/12/2022

    Labeling effect in Western blot is very good, and operations such as fluorescent labeling can be performed to facilitate subsequent detection and analysis.

    06/05/2022

      Production process of APLP1 pays attention to harmonious coexistence with nature, and realizes zero pollution in the production process, demonstrating its persistent pursuit of environmental protection.

      06/23/2020

        The same batch of experiments are very similar, and the reproducibility is very high.

        05/05/2020

          Preparation process is strictly controlled to ensure the quality and safety of the product.

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