apol1
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  • Official Full Name
  • apolipoprotein L, 1
  • Background
  • This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • APOL1; apolipoprotein L, 1; APOL; apolipoprotein L1; APO L; Apo-L; APOL I; ApoL-I; APOL1_HUMAN; APOLI; Apolipoprotein L; Apolipoprotein L I; Apolipoprotein L-I; OTTHUMP00000028705; OTTHUMP00000197952; OTTHUMP00000197984; OTTHUMP00000197985; OTTHUMP00000197986; OTTHUMP00000197987; OTTHUMP00000198062; FSGS4
Cat.#:APOL1-2472HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human APOL1 Protein, MYC/DDK-tagged
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Cat.#:APOL1-3575HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human APOL1, His-tagged
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Cat.#:APOL1-582HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human APOL1 Protein, His-tagged
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Cat.#:APOL1-711HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human APOL1 protein, GST-tagged
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Cat.#:APOL1-8199HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human APOL1 protein, His & GST-tagged
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Cat.#:APOL1-9766HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human APOL1, GST-tagged
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Cat.#:APOL1-3258ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish APOL1
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Cat.#:APOL1-001HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human APOL1 cell lysate
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Involved Pathway

APOL1 involved in several pathways and played different roles in them. We selected most pathways APOL1 participated on our site, such as African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
African trypanosomiasis
IDO1; ICAM1; IL12A; PRKCB; PRKCA; APOA1; HBB-B1; PLCB2; Fasl; IL1B2

Protein Function

APOL1 has several biochemical functions, for example, chloride channel activity, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOL1 itself. We selected most functions APOL1 had, and list some proteins which have the same functions with APOL1. You can find most of the proteins on our site.
Function
Related Protein
Function chloride channel activity
Related Protein SLC26A6L; GABRA5; BEST1; GABRD; CLIC3; SLC26A3.2; GABRA3; CLCN1; TTYH3; SLC26A6
Function lipid binding
Related Protein Fert2; CRABP1B; SH3GL1; BAX; MTTP; Ar; APOA4B.2; FABP1B.1; OSBPL6; PITPNM2
Function protein binding
Related Protein ERGIC1; CRB3; HDAC2; AIDA; FOXN3; CCDC50; NFYA; GTPBP4; ACACB; PDCL

Interacting Protein

APOL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOL1.
CDC23; IGHM