ARID3B
-
Official Full Name
AT rich interactive domain 3B (BRIGHT-like)
-
Overview
AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene. -
Synonyms
ARID3B; AT rich interactive domain 3B (BRIGHT-like); AT rich interactive domain 3B (BRIGHT like); AT-rich interactive domain-containing protein 3B; BDP; DRIL2; bright-like protein; bright and dead ringer protein; ARID domain-containing protein 3B; AT ric;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- DDK
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ARID3B-108H | Recombinant Human ARID3B Protein, DDK-tagged | Insect Cell | DDK | ||
Human | ARID3B-9843H | Recombinant Human ARID3B, GST-tagged | E.coli | GST | 208-562a.a. | |
Human | ARID3B-795H | Recombinant Human ARID3B protein, GST-tagged | Wheat Germ | GST | ||
Human | ARID3B-120HCL | Recombinant Human ARID3B cell lysate | N/A | |||
Human | ARID3B-1136HF | Recombinant Full Length Human ARID3B Protein, GST-tagged | In Vitro Cell Free System | GST | 253 amino acids | |
Mouse | ARID3B-1912M | Recombinant Mouse ARID3B Protein | Mammalian Cell | His | ||
Mouse | ARID3B-707M | Recombinant Mouse ARID3B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ARID3B-707M-B | Recombinant Mouse ARID3B Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ARID3B-5329Z | Recombinant Zebrafish ARID3B | Mammalian Cell | His | ||
Chicken | ARID3B-4582C | Recombinant Chicken ARID3B | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ARID3B involved in several pathways and played different roles in them. We selected most pathways ARID3B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARID3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
ARID3B has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARID3B itself. We selected most functions ARID3B had, and list some proteins which have the same functions with ARID3B. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
DNA binding | MLLT10;Alb;HIST2H2BB;HMGN1;FOXP1A;HDX;ASCL3;ETV5;TRIM30A |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | POU4F3;MYOD1;EN1;KDM6A;CC2D1B;NR4A3;ZNF695;TCF3;CEBPE |
RNA polymerase II distal enhancer sequence-specific DNA binding | NR5A2;SOX10;NR1H4;TAL1;POU4F1;ZBTB16;TFAP2C;MED12;REL |
protein binding | JUP;HIST1H4L;C10orf35;DUSP5;ECSIT;HRASLS5;SF3A2;RPS6KA4;HINT2 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | SMAD4;YBX1;NR4A1;POU3F2;CTCFL;NKX2;SP1;ONECUTL;CARF |
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | ZEB2;FUBP1;CUX1;NFE2L1;TARDBP;CDX1;SPI1;MIXL1;NFATC1 |
ARID3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARID3B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARID3B.
TINF2; POT1; ssdna_dadts
- Q&As
- Reviews
Q&As (10)
Ask a questionARID3B is primarily localized in the nucleus, consistent with its role as a transcription factor. It contains a nuclear localization signal (NLS) that facilitates its transport into the nucleus, where it can interact with DNA and other proteins to regulate gene expression.
As our understanding of ARID3B's functions and involvement in diseases is still evolving, it is premature to determine its potential as a therapeutic target. However, future research may shed light on its relevance in diseases and whether it could be harnessed for therapeutic interventions.
There is limited information regarding mutations or genetic variants specifically linked to ARID3B. Genetic studies examining ARID3B in various diseases or disorders are still ongoing, and further research is required to determine if any specific mutations or genetic variations in ARID3B contribute to specific conditions.
At present, there is limited information regarding diseases or disorders specifically linked to ARID3B mutations. However, dysregulation of ARID3B has been implicated in various types of cancer, including hepatocellular carcinoma and neuroblastoma. Further research is needed to understand the specific role of ARID3B mutations in these diseases and to determine if they are associated with other conditions.
Yes, there is evidence suggesting that ARID3B plays a role in embryonic development. Studies in mice have shown that ARID3B is expressed in early embryonic stages and is involved in the regulation of cell growth and survival during development. However, the precise mechanisms and targets of ARID3B in embryogenesis are still not fully understood.
Yes, there is evidence suggesting that ARID3B plays a role in neural development and function. Studies have shown that ARID3B is highly expressed in the developing brain and is involved in neuronal differentiation and survival. It may also be involved in neural stem cell maintenance and gliogenesis, contributing to the formation and function of the nervous system.
The regulatory elements and transcription factors that control ARID3B expression are not well-characterized. However, some studies suggest that ARID3B expression can be regulated by signaling pathways such as Wnt and Notch, as well as through epigenetic modifications like DNA methylation and histone modifications. Further research is needed to fully elucidate the regulatory mechanisms governing ARID3B expression.
ARID3B has been found to interact with various proteins involved in gene regulation and embryonic development. It has been reported to associate with transcription factors such as BRN2 and SOX2, as well as chromatin remodeling complexes like BAF and NuRD. These interactions suggest that ARID3B collaborates with other factors to regulate gene expression and cellular processes.
Due to the limited knowledge about ARID3B, the current research focus is primarily directed towards understanding its molecular functions, interaction partners, and potential roles in development and disease. Researchers are exploring its involvement in gene regulation, embryonic development, and potentially identifying any links to specific diseases or disorders.
While ARID3A and ARID3B are related proteins, they have distinct functions and expression patterns. ARID3B is expressed in a more restricted manner compared to ARID3A, with higher levels observed in the brain and testis. Furthermore, ARID3B has been found to have a different DNA binding specificity compared to ARID3A.
Customer Reviews (8)
Write a reviewARID3B protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.
The ARID3B protein exhibits exceptional quality, making it an ideal choice to meet my experimental requirements.
They offer comprehensive technical support, including responsive customer service, availability of product information, and timely delivery of the product.
The manufacturer's responsive and knowledgeable support system promptly addresses any questions or concerns I may have, greatly streamlining my research process.
the manufacturer's customer-centric approach highlights their focus on ensuring my satisfaction.
The manufacturer's commitment to customer satisfaction extends beyond providing the protein itself.
This commitment ensures that I have access to the most advanced and reliable protein available, enhancing the integrity and impact of my experiments.
ARID3B protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.
Ask a Question for All ARID3B Products
Required fields are marked with *
My Review for All ARID3B Products
Required fields are marked with *