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ARID3B

  • Official Full Name

    AT rich interactive domain 3B (BRIGHT-like)

  • Overview

    AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene.
  • Synonyms

    ARID3B; AT rich interactive domain 3B (BRIGHT-like); AT rich interactive domain 3B (BRIGHT like); AT-rich interactive domain-containing protein 3B; BDP; DRIL2; bright-like protein; bright and dead ringer protein; ARID domain-containing protein 3B; AT ric;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ARID3B-108H Recombinant Human ARID3B Protein, DDK-tagged Insect Cell DDK
Human ARID3B-9843H Recombinant Human ARID3B, GST-tagged E.coli GST 208-562a.a.
Human ARID3B-795H Recombinant Human ARID3B protein, GST-tagged Wheat Germ GST
Human ARID3B-120HCL Recombinant Human ARID3B cell lysate N/A
Human ARID3B-1136HF Recombinant Full Length Human ARID3B Protein, GST-tagged In Vitro Cell Free System GST 253 amino acids
Mouse ARID3B-1912M Recombinant Mouse ARID3B Protein Mammalian Cell His
Mouse ARID3B-707M Recombinant Mouse ARID3B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ARID3B-707M-B Recombinant Mouse ARID3B Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ARID3B-5329Z Recombinant Zebrafish ARID3B Mammalian Cell His
Chicken ARID3B-4582C Recombinant Chicken ARID3B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ARID3B involved in several pathways and played different roles in them. We selected most pathways ARID3B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARID3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ARID3B has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARID3B itself. We selected most functions ARID3B had, and list some proteins which have the same functions with ARID3B. You can find most of the proteins on our site.

Function Related Protein
DNA bindingMLLT10;Alb;HIST2H2BB;HMGN1;FOXP1A;HDX;ASCL3;ETV5;TRIM30A
RNA polymerase II core promoter proximal region sequence-specific DNA bindingPOU4F3;MYOD1;EN1;KDM6A;CC2D1B;NR4A3;ZNF695;TCF3;CEBPE
RNA polymerase II distal enhancer sequence-specific DNA bindingNR5A2;SOX10;NR1H4;TAL1;POU4F1;ZBTB16;TFAP2C;MED12;REL
protein bindingJUP;HIST1H4L;C10orf35;DUSP5;ECSIT;HRASLS5;SF3A2;RPS6KA4;HINT2
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingSMAD4;YBX1;NR4A1;POU3F2;CTCFL;NKX2;SP1;ONECUTL;CARF
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific bindingZEB2;FUBP1;CUX1;NFE2L1;TARDBP;CDX1;SPI1;MIXL1;NFATC1

ARID3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARID3B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARID3B.

TINF2; POT1; ssdna_dadts

  • Q&As
  • Reviews

Q&As (10)

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Is ARID3B localized to specific cellular compartments? 11/25/2022

ARID3B is primarily localized in the nucleus, consistent with its role as a transcription factor. It contains a nuclear localization signal (NLS) that facilitates its transport into the nucleus, where it can interact with DNA and other proteins to regulate gene expression.

Can ARID3B be a potential therapeutic target? 10/17/2022

As our understanding of ARID3B's functions and involvement in diseases is still evolving, it is premature to determine its potential as a therapeutic target. However, future research may shed light on its relevance in diseases and whether it could be harnessed for therapeutic interventions.

Are there any known mutations or genetic variants associated with ARID3B? 07/25/2020

There is limited information regarding mutations or genetic variants specifically linked to ARID3B. Genetic studies examining ARID3B in various diseases or disorders are still ongoing, and further research is required to determine if any specific mutations or genetic variations in ARID3B contribute to specific conditions.

Are there any known diseases or disorders associated with ARID3B mutations? 05/24/2018

At present, there is limited information regarding diseases or disorders specifically linked to ARID3B mutations. However, dysregulation of ARID3B has been implicated in various types of cancer, including hepatocellular carcinoma and neuroblastoma. Further research is needed to understand the specific role of ARID3B mutations in these diseases and to determine if they are associated with other conditions.

Is ARID3B involved in embryonic development? 04/07/2018

Yes, there is evidence suggesting that ARID3B plays a role in embryonic development. Studies in mice have shown that ARID3B is expressed in early embryonic stages and is involved in the regulation of cell growth and survival during development. However, the precise mechanisms and targets of ARID3B in embryogenesis are still not fully understood.

Is there any evidence of ARID3B involvement in neural development or function? 08/05/2017

Yes, there is evidence suggesting that ARID3B plays a role in neural development and function. Studies have shown that ARID3B is highly expressed in the developing brain and is involved in neuronal differentiation and survival. It may also be involved in neural stem cell maintenance and gliogenesis, contributing to the formation and function of the nervous system.

Are there any known regulatory elements or transcription factors that control ARID3B expression? 05/21/2017

The regulatory elements and transcription factors that control ARID3B expression are not well-characterized. However, some studies suggest that ARID3B expression can be regulated by signaling pathways such as Wnt and Notch, as well as through epigenetic modifications like DNA methylation and histone modifications. Further research is needed to fully elucidate the regulatory mechanisms governing ARID3B expression.

Does ARID3B have any known interaction partners? 10/06/2016

ARID3B has been found to interact with various proteins involved in gene regulation and embryonic development. It has been reported to associate with transcription factors such as BRN2 and SOX2, as well as chromatin remodeling complexes like BAF and NuRD. These interactions suggest that ARID3B collaborates with other factors to regulate gene expression and cellular processes.

What are the current research directions for ARID3B? 10/04/2016

Due to the limited knowledge about ARID3B, the current research focus is primarily directed towards understanding its molecular functions, interaction partners, and potential roles in development and disease. Researchers are exploring its involvement in gene regulation, embryonic development, and potentially identifying any links to specific diseases or disorders.

How is ARID3B different from ARID3A? 05/29/2016

While ARID3A and ARID3B are related proteins, they have distinct functions and expression patterns. ARID3B is expressed in a more restricted manner compared to ARID3A, with higher levels observed in the brain and testis. Furthermore, ARID3B has been found to have a different DNA binding specificity compared to ARID3A.

Customer Reviews (8)

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Reviews
01/11/2023

    ARID3B protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.

    12/12/2022

      The ARID3B protein exhibits exceptional quality, making it an ideal choice to meet my experimental requirements.

      12/17/2021

        They offer comprehensive technical support, including responsive customer service, availability of product information, and timely delivery of the product.

        08/25/2021

          The manufacturer's responsive and knowledgeable support system promptly addresses any questions or concerns I may have, greatly streamlining my research process.

          07/26/2020

            the manufacturer's customer-centric approach highlights their focus on ensuring my satisfaction.

            01/22/2020

              The manufacturer's commitment to customer satisfaction extends beyond providing the protein itself.

              11/04/2018

                This commitment ensures that I have access to the most advanced and reliable protein available, enhancing the integrity and impact of my experiments.

                04/22/2017

                  ARID3B protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.

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