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ARID3C

  • Official Full Name

    AT rich interactive domain 3C (BRIGHT-like)

  • Overview

    This gene is a member of the ARID (AT-rich interaction domain) family of proteins. The ARID domain is a helix-turn-helix motif-based DNA-binding domain. ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.
  • Synonyms

    ARID3C; AT rich interactive domain 3C (BRIGHT-like); AT rich interactive domain 3C (BRIGHT like); AT-rich interactive domain-containing protein 3C; AT rich interactive domain containing protein 3C; ARID domain containing protein 3C; ARID domain-containing protein 3C;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ARID3C-796H Recombinant Human ARID3C protein, GST-tagged Wheat Germ GST
Human ARID3C-3679H Recombinant Human ARID3C, His-tagged E.Coli or Yeast His 412
Human ARID3C-2692H Recombinant Human ARID3C Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ARID3C-1352HF Recombinant Full Length Human ARID3C Protein, GST-tagged In Vitro Cell Free System GST 412 amino acids
Mouse Arid3c-3678M Recombinant Mouse Arid3c, His-tagged E.Coli or Yeast His 409
Mouse ARID3C-1913M Recombinant Mouse ARID3C Protein Mammalian Cell His
Mouse Arid3c-1699M Recombinant Mouse Arid3c Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ARID3C-708M-B Recombinant Mouse ARID3C Protein Pre-coupled Magnetic Beads HEK293
Mouse ARID3C-708M Recombinant Mouse ARID3C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ARID3C involved in several pathways and played different roles in them. We selected most pathways ARID3C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARID3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ARID3C has several biochemical functions, for example, DNA binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARID3C itself. We selected most functions ARID3C had, and list some proteins which have the same functions with ARID3C. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF566;FOXF1;G3BP1;SUB1B;VPS72;TOP1;WRNIP1;FAM171B;ASCL4
chromatin bindingTCF7L1A;SIN3A;SOX9;GATA5;TP73;CBX7;JARID2;RCC1;NCOA3

ARID3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARID3C here. Most of them are supplied by our site. Hope this information will be useful for your research of ARID3C.

  • Q&As
  • Reviews

Q&As (12)

Ask a question
Is ARID3C exclusively expressed in B cells? 11/14/2022

While ARID3C is primarily known for its role in B-cell development and function, it has also been reported to be expressed in other cell types, including T cells, myeloid cells, and some non-immune cell types. The exact significance and function of ARID3C in these cell types are still being explored.

Has ARID3C been implicated in any specific diseases or disorders? 08/14/2022

ARID3C has been implicated in various diseases and disorders, including B-cell lymphomas, autoimmune disorders, and some viral infections. Dysregulation of ARID3C expression or activity has been observed in certain types of B-cell lymphomas, suggesting a potential role in tumor development. Additionally, ARID3C has been shown to play a role in the pathogenesis of autoimmune disorders, as its expression is altered in these conditions. Studies have also demonstrated the involvement of ARID3C in viral infections, where it can affect the immune response to the virus.

Are there any known small molecule inhibitors or activators of ARID3C? 11/02/2020

Currently, there are no known small molecule inhibitors or activators specifically targeting ARID3C. Research efforts are focused on elucidating the underlying mechanisms of ARID3C regulation and identifying potential therapeutic agents that can modulate its activity. Development of small molecule inhibitors or activators targeting ARID3C may hold promise as future therapeutic interventions, but further studies are required.

Can ARID3C be targeted for therapeutic interventions? 10/22/2020

Modulating ARID3C activity holds potential for therapeutic interventions, particularly in diseases involving B-cell dysregulation. However, more research is needed to fully understand the complex regulatory networks involving ARID3C and to develop targeted approaches for its manipulation.

Is ARID3C associated with any diseases? 03/07/2020

Studies have suggested that aberrant expression or dysfunction of ARID3C may be associated with certain types of cancers, including B-cell lymphomas. Further research is needed to fully understand the role of ARID3C in cancer development and progression.

What are the potential therapeutic implications of targeting ARID3C? 10/15/2019

Targeting ARID3C could have therapeutic implications in diseases involving B-cell dysregulation, such as B-cell lymphomas or autoimmune disorders. By modulating ARID3C activity, it may be possible to influence B-cell development, antibody production, and immune response, potentially leading to novel treatment approaches.

Are there any known genetic variants or mutations in ARID3C? 06/03/2019

Currently, no specific genetic variants or mutations in ARID3C have been widely reported in the literature. However, studies are ongoing to identify potential genetic variations and their association with disease susceptibility and progression.

Is ARID3C associated with any specific signaling pathways? 05/28/2019

ARID3C has been reported to be associated with several signaling pathways. It can be activated by various cytokines, such as Interleukin-2 (IL-2) and Interleukin-7 (IL-7), which are important for B-cell development and function. Additionally, ARID3C has been found to interact with components of the Wnt signaling pathway, suggesting a potential role in regulating cell proliferation and differentiation. The exact mechanisms and significance of these associations are still being investigated.

Are there any known interacting proteins with ARID3C? 02/22/2019

ARID3C can interact with a variety of proteins, including other transcription factors, co-regulators, chromatin remodeling complexes, and DNA repair proteins. The specific interacting partners may vary depending on the cellular context and the target genes being regulated.

What are the target genes regulated by ARID3C? 11/13/2017

ARID3C is known to regulate the expression of genes involved in B-cell development and function. It can interact with other transcription factors, co-regulators, and chromatin remodeling complexes to modulate the expression of these genes.

What are the cellular processes influenced by ARID3C? 05/13/2017

ARID3C is involved in several cellular processes, including cell proliferation, differentiation, apoptosis, and immune response. It plays a crucial role in B-cell development and antibody production by regulating the expression of genes involved in these processes.

Are there any known interactions or regulators of ARID3C? 02/18/2017

ARID3C can interact with other transcription factors, such as PU.1 and OCT-2, to form complexes that regulate gene expression in B cells. It can also be regulated by post-translational modifications, such as phosphorylation, which can modulate its activity.

Customer Reviews (8)

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Reviews
09/30/2022

    This level of support ensures that researchers have a seamless experience, enabling them to focus on their research goals without worrying about logistical or technical concerns.

    03/06/2022

      With their assistance, I can confidently delve into the intricacies of ARID3C and make significant contributions to the field of ARID3C-related research.

      06/27/2020

        This high-quality protein serves as an invaluable tool in unraveling the intricate mechanisms governed by ARID3C, enabling me to gain deeper insights into its functions and implications.

        05/25/2019

          Its versatility in various biological applications, along with its compatibility with different techniques, strongly recommend it as a preferred reagent for researchers in the field.

          02/28/2019

            They consistently stay at the forefront of scientific advancements and customer feedback, allowing them to refine the ARID3C protein based on emerging research trends.

            02/06/2018

              ARID3C protein offers numerous advantages in trials, ranging from its stability and bioactivity to the manufacturer's commitment to customer support.

              12/18/2017

                researchers highly appreciate ARID3C protein for its excellent performance in ELISA assays and protein electron microscopy structure analysis.

                07/10/2017

                  An outstanding aspect of the manufacturer of the ARID3C protein is their commitment to providing excellent technical support.

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