ARPC5A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ARPC5A-9728Z | Recombinant Zebrafish ARPC5A | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ARPC5A involved in several pathways and played different roles in them. We selected most pathways ARPC5A participated on our site, such as Endocytosis, Regulation of actin cytoskeleton, Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPC5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | CXCR4B;ARF6B;SH3GLB1A;VPS35;ASAP2A;WIPF1;CDC42;TGFBR1A;CAPZA3 |
| Regulation of actin cytoskeleton | ACTG1;FN1;GNA13A;ITGA4;PFN3;FGF9;PPP1R12B;FGF18A;HRASA |
| Salmonella infection | TJP1;DYNC1LI2;IL8L1;MAPK14B;IL1A;NFKB1;ARPC5LB;MAPK8;IL6 |
ARPC5A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARPC5A itself. We selected most functions ARPC5A had, and list some proteins which have the same functions with ARPC5A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
ARPC5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPC5A here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPC5A.
- Q&As
- Reviews
Q&As (8)
Ask a questionAs ARPC5A is involved in actin dynamics and cell motility, it has the potential to be a therapeutic target in diseases where dysregulation of these processes occurs, including cancer. However, additional research is necessary to determine the feasibility and efficacy of targeting ARPC5A in cancer therapy.
The ARPC5A protein has a seven-bladed beta-propeller domain, which is characteristic of the ARPC5 subfamily. It also contains an actin-binding domain that interacts with actin filaments and helps in the branching process.
Yes, the expression of ARPC5A can be regulated at the transcriptional level, where specific transcription factors bind to its promoter region. Additionally, post-transcriptional mechanisms, such as microRNAs or RNA-binding proteins, can also influence ARPC5A expression.
Yes, ARPC5A interacts with multiple proteins to regulate actin dynamics and cellular processes. It interacts with other subunits of the ARP2/3 complex, as well as actin-binding proteins and regulatory factors involved in actin filament assembly and organization.
Yes, ARPC5A plays a crucial role in cell migration, as it is part of the ARP2/3 complex, which is involved in actin filament nucleation and branching during lamellipodia formation. Disruption of ARPC5A function can affect cell migration and motility.
No specific diseases have been directly associated with ARPC5A mutations or dysregulation. However, since ARPC5A contributes to actin dynamics, alterations in its expression or function could potentially contribute to disease states, such as cancer metastasis or neuronal disorders.
Various genetic variations, such as single nucleotide polymorphisms (SNPs), have been identified in the ARPC5A gene. Some of these variations may impact the expression or function of ARPC5A and potentially contribute to individual differences in actin dynamics and cellular processes.
As ARPC5A is a subunit of the ARP2/3 complex involved in actin regulation, targeting ARPC5A directly may be challenging due to its essential role in normal cellular processes. However, understanding ARPC5A's involvement in disease pathways and its interaction with specific proteins within those pathways could lead to the development of indirect therapeutic strategies targeting ARPC5A-related functions.
Customer Reviews (3)
Write a reviewthe ARPC5A protein's high quality, stellar technical support, and compatibility with diverse experimental approaches make it an optimal choice for meeting my research needs.
Its usage in these techniques is highly praised by scientists worldwide, attesting to its effectiveness and significance in advancing scientific knowledge and understanding.
the ARPC5A protein's compatibility with various experimental techniques adds to its versatility.
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