ARPC5L
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Official Full Name
actin related protein 2/3 complex, subunit 5-like
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Synonyms
Arpc5l; actin-related protein 2/3 complex subunit 5-like protein; ARC16-2; arp2/3 complex 16 kDa subunit 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ARPC5L-850H | Recombinant Human ARPC5L protein, GST-tagged | Wheat Germ | GST | ||
Human | ARPC5L-128HCL | Recombinant Human ARPC5L cell lysate | N/A | |||
Human | ARPC5L-1444HF | Recombinant Full Length Human ARPC5L Protein, GST-tagged | In Vitro Cell Free System | GST | 153 amino acids | |
Mouse | ARPC5L-1971M | Recombinant Mouse ARPC5L Protein | Mammalian Cell | His | ||
Mouse | ARPC5L-751M | Recombinant Mouse ARPC5L Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ARPC5L-751M-B | Recombinant Mouse ARPC5L Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Arpc5l-3107R | Recombinant Rat Arpc5l, His-tagged | E.Coli or Yeast | His | 153 | |
Rat | ARPC5L-800R | Recombinant Rat ARPC5L Protein | Mammalian Cell | His | ||
Rat | ARPC5L-456R | Recombinant Rat ARPC5L Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | ARPC5L-456R-B | Recombinant Rat ARPC5L Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
ARPC5L involved in several pathways and played different roles in them. We selected most pathways ARPC5L participated on our site, such as Endocytosis, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPC5L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Endocytosis | GRK1;SNX6;RAB11FIP4B;HRASA;CBL;SNF8;RAB11FIP4A;SNX1B;RAB11BB |
Fc gamma R-mediated phagocytosis | NCF1;PIK3R1;PPAP2A;LIMK2;WAS;PIK3CD;PPAP2C;PRKCE;ASAP2 |
Regulation of actin cytoskeleton | NRAS;HRASB;ARHGEF1;ARHGEF4;FGF8;FGF21;GSNB;PIKFYVE;WASLA |
Bacterial invasion of epithelial cells | SEPT9;PXN;SEPT1;ARPC1B;PTK2;BCAR1;DOCK1;CBLC;CTTN |
Pathogenic Escherichia coli infection | FYN;ROCK2;PRKCA;TUBB7P;TUBB6;TUBAL3;ACTG1;NCL;YWHAZ |
Shigellosis | HCLS1;U2AF1L4;UBE2D2;ACTB;IKBKB;MAPK11;ROCK1;ARPC5L;DIAPH1 |
Salmonella infection | MAPK10;CCL4;TLR4;IL8L1;FLNB;ACTB;KLC2;CDC42L2;CDC42L |
ARPC5L has several biochemical functions, for example, actin binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPC5L itself. We selected most functions ARPC5L had, and list some proteins which have the same functions with ARPC5L. You can find most of the proteins on our site.
Function | Related Protein |
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actin binding | EVLB;FSCN2;FKBP15;MYOT;ANTXR2A;MTSS1L;ACE;CNN3A;COBL |
molecular_function | MXRA8;FADS3;LIPM;SPP2;LINS;TMC6B;TIMM8A2;CCDC187;PTER |
ARPC5L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPC5L here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPC5L.
ACTR3B; GADD45G; ARPC4; Tpx2; Itga5; FLNA; CDK2; ARRB2; MYH9; MYH11; IQGAP1; CAPZA2; Tpm1; Actb; ACTR2; DBN1; Flot2; Myh10
- Q&As
- Reviews
Q&As (7)
Ask a questionARPC5L expression has been observed in a wide range of tissues and cell types, suggesting it is likely expressed ubiquitously. Nonetheless, its expression levels may vary depending on the cell type or tissue and can be regulated in a context-specific manner.
Yes, ARPC5L depletion or disruption can lead to cellular abnormalities. Impaired actin cytoskeleton regulation, caused by ARPC5L dysfunction, can affect various cellular processes such as cell shape, migration, and division.
There is evidence suggesting that ARPC5L is involved in neuronal development and synaptic plasticity. It participates in the formation of dendritic spines, which are essential for synaptic connections and neuronal communication.
Currently, there are no specific drugs available that directly target ARPC5L or the ARP2/3 complex. However, various small molecules and compounds that indirectly modulate actin dynamics are under investigation for their potential in therapeutics targeting Actin-related processes.
ARPC5L interacts with various proteins and complexes involved in actin dynamics and cell signaling. Some of the known interacting partners include other subunits of the ARP2/3 complex, actin-binding proteins, signaling molecules like Rho GTPases, and adaptor proteins involved in membrane trafficking.
Yes, ARPC5L plays a role in cytokinesis, the process of cell division. It helps in the formation of the actin-based contractile ring, which drives the separation of daughter cells during cytokinesis.
Currently, there are no known specific genetic disorders directly attributed to ARPC5L mutations. However, abnormalities in actin cytoskeleton regulation, which ARPC5L is involved in, can contribute to various developmental and disease-related phenotypes.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to delivering a high-quality product further enhances its reputation and guarantees its suitability for a wide range of research applications.
In addition to its outstanding quality, the manufacturer of the ARPC5L protein provides excellent technical support, which is a valuable asset for researchers
The ARPC5L protein is of exceptional quality, making it an ideal choice to meet my experimental requirements.
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