ART3
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Official Full Name
ADP-ribosyltransferase 3
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Overview
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction;which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of;the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants;encoding different isoforms have been found for this gene. -
Synonyms
ART3; ADP-ribosyltransferase 3; ecto-ADP-ribosyltransferase 3; mono-ADP-ribosyltransferase; mono(ADP-ribosyl)transferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3; FLJ26404;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Mouse
- HEK293
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ART3-569H | Recombinant Human ART3, His tagged | Human Cell | N/A |
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| Human | ART3-869H | Recombinant Human ART3 protein, GST-tagged | Wheat Germ | GST |
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| Human | ART3-1148HCL | Recombinant Human ART3 cell lysate | Human Cell | N/A |
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| Human | ART3-1018HF | Recombinant Full Length Human ART3 Protein, GST-tagged | In Vitro Cell Free System | GST | 389 amino acids |
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| Mouse | ART3-1990M | Recombinant Mouse ART3 Protein | Mammalian Cell | His |
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| Mouse | ART3-764M | Recombinant Mouse ART3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ART3-764M-B | Recombinant Mouse ART3 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Cynomolgus Monkey | ART3-314C | Recombinant Cynomolgus ART3 Protein, His-tagged | Mammalian Cell | His |
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| Cynomolgus Monkey | ART3-64C-B | Recombinant Cynomolgus Monkey ART3 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Cynomolgus Monkey | ART3-64C | Recombinant Cynomolgus Monkey ART3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
ART3 involved in several pathways and played different roles in them. We selected most pathways ART3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ART3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ART3 has several biochemical functions, for example, NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ART3 itself. We selected most functions ART3 had, and list some proteins which have the same functions with ART3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | ART5;ART3;Art2b;MADPRT;CHAT2;CHAT1;SIRT6;ART1 |
| NAD+ ADP-ribosyltransferase activity | PARP16;GIG2P;TNKS2;PARP14;PARP2;ART1;GIG2G;PARP11;GIG2E |
ART3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ART3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ART3.
ALCAM
- Q&As
- Reviews
Q&As (7)
Ask a questionART3 ADP-ribosylates specific arginine residues on target proteins, including CD28, a critical co-stimulatory molecule in T cell activation.
Mutations in the ART3 gene have not been directly linked to specific diseases or disorders in humans so far.
The precise regulation of ART3 gene expression is not well characterized, but it may be influenced by various cellular and immune signaling pathways.
ART3 activity depends on the availability of NAD+ as a substrate and can also be influenced by various cellular signaling pathways related to immune responses.
Dysregulated ADP-ribosylation, including ART3 activity, has been implicated in various diseases. However, the specific role of ART3 in these conditions requires further investigation.
Animal models, such as ART3 knockout mice, have been generated to investigate the role of ART3 in vivo, providing insights into its physiological functions.
ART3 transfers ADP-ribose from NAD+ to specific target proteins, modifying their structure and function.
Customer Reviews (3)
Write a reviewThe ART3 Protein boasts remarkable stability, ensuring its integrity is maintained during storage and experimentation.
One remarkable aspect of the ART3 Protein is the outstanding technical support provided by the manufacturer.
Equally noteworthy is the remarkable technical support provided by the manufacturer.
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