ASB10
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Official Full Name
ankyrin repeat and SOCS box containing 10
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Overview
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. -
Synonyms
ASB10; ankyrin repeat and SOCS box containing 10; ankyrin repeat and SOCS box protein 10; ASB 10; OTTHUMP00000211301; OTTHUMP00000211302; OTTHUMP00000211303; ankyrin repeat and SOCS box-containing 10;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ASB10-883H | Recombinant Human ASB10 protein, GST-tagged | Wheat Germ | GST |
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| Human | ASB10-1346HF | Recombinant Full Length Human ASB10 Protein, GST-tagged | In Vitro Cell Free System | GST | 467 amino acids |
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| Mouse | ASB10-2006M | Recombinant Mouse ASB10 Protein | Mammalian Cell | His |
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| Mouse | ASB10-773M | Recombinant Mouse ASB10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ASB10-773M-B | Recombinant Mouse ASB10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | ASB10-4608Z | Recombinant Zebrafish ASB10 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
ASB10 involved in several pathways and played different roles in them. We selected most pathways ASB10 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | CREB1B;TPP2;AP2S1;DNM2;SIGLEC11;OSCAR;FGFR1B;UBE2E3;GAN |
| Antigen processing: Ubiquitination & | PJA2;ASB13;TRIM41;UFL1;RNF220;TRIM9;RNF41;LRR1;ARIH2 |
| Proteasome degradation | FBXO3;TRIM69;LTN1;RNF41;WWP1;RNF19B;TPP2;DTX3L;ASB13 |
| Class I MHC mediated antigen processing & | TRIM69;ASB11;ERAP1;UBR2;RBCK1;B2ML;ASB3;TRIM63;FBXO27 |
| presentation | LRSAM1;ERAP2;TRIM39;UBE2V2;B2ML;CTSL2;ARIH2;FCGR1B;ASB10 |
| Immune System | GBP1;LGALS3;WIPF3;GHRB;CRTAM;CLEC2H;CLEC4D;KIF3B;DEFB4A |
ASB10 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB10 itself. We selected most functions ASB10 had, and list some proteins which have the same functions with ASB10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | WBP1LB;ASNSD1;VSTM5;SLC41A1;TMEM248;LHFPL2B;FAIMA;IBSP;BCAS3 |
ASB10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB10.
- Q&As
- Reviews
Q&As (7)
Ask a questionASB10 has been suggested to play a role in neuronal development and maturation, possibly by regulating the abundance of specific proteins involved in these processes.
While ASB10 expression is highest in the brain, it has also been detected in low levels in other tissues like the heart, testis, and skeletal muscle.
ASB10 has been implicated in neurological disorders, with some studies suggesting its involvement in autism spectrum disorders and cognitive impairments.
ASB10's participation in protein quality control mechanisms, such as targeting misfolded or aggregated proteins for degradation, remains speculative and requires further investigation.
ASB10 has been implicated in the regulation of synaptic plasticity, which is crucial for learning and memory formation, suggesting its potential involvement in cognitive processes.
The involvement of ASB10 in neurodegenerative diseases, such as Alzheimer's and Parkinson's, has not been extensively studied, and more research is needed to establish any associations.
Yes, ASB10 can interact with various proteins through its ankyrin repeat domain, potentially influencing protein degradation and cellular signaling.
Customer Reviews (3)
Write a reviewFrom recombinant protein production to modification or labeling services, the company is committed to assisting researchers in obtaining the ASB10 protein in the format and specifications required for their particular studies.
the manufacturer understands the importance of customization and can offer tailored solutions to meet specific research needs.
Whether it be troubleshooting issues, offering experimental guidance, or addressing any concerns, the manufacturer's technical support ensures that researchers have a reliable and knowledgeable resource to rely on.
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