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ASB11

  • Official Full Name

    ankyrin repeat and SOCS box containing 11

  • Overview

    The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    ASB11; ankyrin repeat and SOCS box containing 11; ankyrin repeat and SOCS box protein 11; DKFZp779E2460; ASB-11; ankyrin repeat domain-containing SOCS box protein ASB11; MGC119168; MGC119169;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ASB11-884H Recombinant Human ASB11 protein, GST-tagged Wheat Germ GST
Human ASB11-349H Recombinant Human ASB11 Protein, His-tagged E.coli His
Human ASB11-01H Recombinant Human ASB11 Protein, His-tagged E.coli His
Human ASB11-1355HF Recombinant Full Length Human ASB11 Protein, GST-tagged In Vitro Cell Free System GST 323 amino acids
Mouse ASB11-2007M Recombinant Mouse ASB11 Protein Mammalian Cell His
Mouse ASB11-774M Recombinant Mouse ASB11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ASB11-774M-B Recombinant Mouse ASB11 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ASB11-422R Recombinant Rhesus monkey ASB11 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ASB11-251R Recombinant Rhesus Macaque ASB11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ASB11-251R-B Recombinant Rhesus Macaque ASB11 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ASB11-12807Z Recombinant Zebrafish ASB11 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ASB11 Related Articles

ASB11 involved in several pathways and played different roles in them. We selected most pathways ASB11 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemPDPK1A;CD300C;AGO1;GM11711;ASB6;CDKN1B;CD207;LILRA2;UBA5
Antigen processing: Ubiquitination &ampSPSB1;RNF182;TRIM11;BLMH;SH3RF1;TRIM39;ARIH2;RNF138;VPRBP
Proteasome degradationASB7;UBE2V1;TRIM69;ASB8;ASB11;UBE2L6;FBXO27;TRIM50;RNF220
Class I MHC mediated antigen processing &ampASB13;ASB6;SPSB4;CTSL2;TRIM41;TRIM63;RNF138;UBR2;RNF182
presentationCYBB;ASB8;RNF41;MKRN1;CTSL1;FBXO3;VPRBP;RNF25;FCGR1B
Immune SystemRNF216;TRIM56;LGALS9;IRAK3;ASB6;WSB1;TAX1BP1;LILRB5;NLRP4E

ASB11 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB11 itself. We selected most functions ASB11 had, and list some proteins which have the same functions with ASB11. You can find most of the proteins on our site.

Function Related Protein
molecular_functionQRICH1;APOL4;FAM210B;Aadacl3;TMEM132A;GALNTL4;COL6A6;GID8A;CLASRP

ASB11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB11.

Fingert, JH; Roos, BR; et al. Analysis of ASB10 variants in open angle glaucoma. HUMAN MOLECULAR GENETICS 21:4543-4548(2012).
da Silva, MAS; Tee, JM; et al. Essential Role for the d-Asb11 cul5 Box Domain for Proper Notch Signaling and Neural Cell Fate Decisions In Vivo. PLOS ONE 5:-(2010).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
Does ASB11 have RNA-binding properties? 04/25/2023

ASB11 does not possess known RNA-binding domains or motifs, and its functions primarily revolve around protein degradation mechanisms.

Does ASB11 have a role in neural development? 04/18/2023

The involvement of ASB11 in neural development is not extensively studied, and further research is needed to determine if it plays a role in this process.

Is ASB11 associated with synaptic plasticity? 12/08/2022

The specific association of ASB11 with synaptic plasticity remains unknown, and more research is required to elucidate its potential role in modulating this process.

Does ASB11 interact with other proteins? 06/18/2022

Yes, ASB11 can interact with different protein substrates, facilitating their ubiquitination and subsequent degradation through the ubiquitin-proteasome system.

Can ASB11 influence cell growth and proliferation? 05/15/2019

ASB11's association with protein degradation pathways implies its potential role in regulating cell growth and proliferation, although specific mechanisms are still being investigated.

Is ASB11 involved in cellular signaling pathways? 07/05/2018

ASB11's SOCS box domain suggests its possible involvement in modulating cellular signaling by targeting specific proteins for degradation.

Can ASB11 regulate protein turnover and stability? 02/09/2017

Yes, ASB11 is believed to have a role in regulating protein turnover and stability through its ability to target proteins for degradation via the ubiquitin-proteasome system.

Customer Reviews (3)

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Reviews
04/16/2023

    the ASB11 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.

    03/20/2017

      Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

      08/31/2016

        Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

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