ASB11
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Official Full Name
ankyrin repeat and SOCS box containing 11
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Overview
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ASB11; ankyrin repeat and SOCS box containing 11; ankyrin repeat and SOCS box protein 11; DKFZp779E2460; ASB-11; ankyrin repeat domain-containing SOCS box protein ASB11; MGC119168; MGC119169;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Involved Pathway
- Protein Function
- Interacting Protein
- ASB11 Related Articles
ASB11 involved in several pathways and played different roles in them. We selected most pathways ASB11 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adaptive Immune System | PDPK1A;CD300C;AGO1;GM11711;ASB6;CDKN1B;CD207;LILRA2;UBA5 |
Antigen processing: Ubiquitination & | SPSB1;RNF182;TRIM11;BLMH;SH3RF1;TRIM39;ARIH2;RNF138;VPRBP |
Proteasome degradation | ASB7;UBE2V1;TRIM69;ASB8;ASB11;UBE2L6;FBXO27;TRIM50;RNF220 |
Class I MHC mediated antigen processing & | ASB13;ASB6;SPSB4;CTSL2;TRIM41;TRIM63;RNF138;UBR2;RNF182 |
presentation | CYBB;ASB8;RNF41;MKRN1;CTSL1;FBXO3;VPRBP;RNF25;FCGR1B |
Immune System | RNF216;TRIM56;LGALS9;IRAK3;ASB6;WSB1;TAX1BP1;LILRB5;NLRP4E |
ASB11 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB11 itself. We selected most functions ASB11 had, and list some proteins which have the same functions with ASB11. You can find most of the proteins on our site.
Function | Related Protein |
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molecular_function | QRICH1;APOL4;FAM210B;Aadacl3;TMEM132A;GALNTL4;COL6A6;GID8A;CLASRP |
ASB11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB11.
- Q&As
- Reviews
Q&As (7)
Ask a questionASB11 does not possess known RNA-binding domains or motifs, and its functions primarily revolve around protein degradation mechanisms.
The involvement of ASB11 in neural development is not extensively studied, and further research is needed to determine if it plays a role in this process.
The specific association of ASB11 with synaptic plasticity remains unknown, and more research is required to elucidate its potential role in modulating this process.
Yes, ASB11 can interact with different protein substrates, facilitating their ubiquitination and subsequent degradation through the ubiquitin-proteasome system.
ASB11's association with protein degradation pathways implies its potential role in regulating cell growth and proliferation, although specific mechanisms are still being investigated.
ASB11's SOCS box domain suggests its possible involvement in modulating cellular signaling by targeting specific proteins for degradation.
Yes, ASB11 is believed to have a role in regulating protein turnover and stability through its ability to target proteins for degradation via the ubiquitin-proteasome system.
Customer Reviews (3)
Write a reviewthe ASB11 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.
Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.
Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.
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