ASB5
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Official Full Name
ankyrin repeat and SOCS box containing 5
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Overview
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. -
Synonyms
ASB5; ankyrin repeat and SOCS box containing 5; ankyrin repeat and SOCS box protein 5; ASB 5; SOCS box protein ASB 5; SOCS box protein ASB-5; ankyrin repeat and SOCS box-containing 5; ASB-5;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ASB5-894H | Recombinant Human ASB5 protein, GST-tagged | Wheat Germ | GST |
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| Human | ASB5-2529H | Recombinant Human ASB5 protein, His-tagged | E.coli | His | 245-329 aa | |
| Human | ASB5-1357HF | Recombinant Full Length Human ASB5 Protein, GST-tagged | In Vitro Cell Free System | GST | 329 amino acids |
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- ASB5 Related Articles
ASB5 involved in several pathways and played different roles in them. We selected most pathways ASB5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ASB5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ASB5 itself. We selected most functions ASB5 had, and list some proteins which have the same functions with ASB5. You can find most of the proteins on our site.
| Function | Related Protein |
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ASB5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB5.
- Q&As
- Reviews
Q&As (8)
Ask a questionASB5 can interact with different proteins, including ankyrin repeat and SOCS box-containing protein 10 (ASB10), which can modulate ASB5 activity in muscle development.
Yes, several genetic variations in the ASB5 gene have been identified. Some of these variations are associated with muscle-related disorders and cardiac abnormalities.
While ASB5's role in neurodevelopment or neurological disorders is not extensively studied, it may play a part in neuronal differentiation and function. Further research is required to determine its implications in neurological conditions.
Yes, studies have shown that ASB5 is important for muscle development and differentiation, particularly in the formation of skeletal muscle fibers.
Altered ASB5 expression or function has been observed in various conditions, including myopathies, neuropathies, and cardiac diseases. However, further research is needed to fully understand the extent of its involvement in these disorders.
While ASB5 is primarily known for its role in muscle development and protein degradation, it may also participate in other processes, such as cell proliferation and differentiation.
Yes, ASB5 has been implicated in cardiac diseases, including dilated cardiomyopathy and heart failure. It may contribute to the degradation of specific proteins involved in cardiac muscle contraction.
Yes, ASB5 expression can be regulated by signaling pathways involved in muscle development, such as the Notch signaling pathway.
Customer Reviews (3)
Write a reviewTheir expertise and commitment to customer satisfaction are truly commendable, ensuring that I have access to the necessary resources to overcome any experimental hurdles that may arise.
he ASB5 protein is an exceptional choice that meets the highest standards of quality, perfectly catering to my experimental requirements.
the ASB5 protein's well-documented properties and thoroughly tested functionality give me the confidence to integrate it seamlessly into my experimental setup.
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