ASB6
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Official Full Name
ankyrin repeat and SOCS box containing 6
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Overview
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. -
Synonyms
ASB6; ankyrin repeat and SOCS box containing 6; ankyrin repeat and SOCS box protein 6; ASB 6; FLJ20548; MGC1024; ankyrin repeat and SOCS box-containing 6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- SUMO
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ASB6-9919H | Recombinant Human ASBHis-tagged | E.coli | His | 1-163a.a. | |
| Human | ASB6-895H | Recombinant Human ASB6 protein, GST-tagged | Wheat Germ | GST |
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| Human | ASB6-8661HCL | Recombinant Human ASB6 293 Cell Lysate | HEK293 | N/A |
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| Human | ASB6-1359HF | Recombinant Full Length Human ASB6 Protein, GST-tagged | In Vitro Cell Free System | GST | 197 amino acids |
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| Human | ASB6-4824H | Recombinant Human ASB6 protein, His-SUMO-tagged | E.coli | His-SUMO | 1-197aa |
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| Mouse | Asb6-1735M | Recombinant Mouse Asb6 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Zebrafish | ASB6-2759Z | Recombinant Zebrafish ASB6 | Mammalian Cell | His |
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| Chicken | ASB6-2391C | Recombinant Chicken ASB6 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
ASB6 involved in several pathways and played different roles in them. We selected most pathways ASB6 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | RNF4;SH3RF1;SPSB2;DYNC1I2;IGKV1-5;NRG4;DYNC1H1;NA;FGF10B |
| Antigen processing: Ubiquitination & | RNF14;LRSAM1;TRIM69;PJA2;FBXO3;RNF6;UBE2L6;ARIH2;SPSB1 |
| Proteasome degradation | UBE2V1;UBR2;RNF19B;SH3RF1;KLHL21;ASB17;ASB13;UCHL3;RNF4 |
| Class I MHC mediated antigen processing & | BLMH;ASB8;UBE2U;RNF19B;RNF34;ASB6;KLHL21;CTSS;WWP1 |
| presentation | MKRN1;LRSAM1;UBE2J2;GAN;LRRC41;TRIM69;SPSB1;STUB1;ASB14 |
| Immune System | EVL;AP1B1;HCST;DTX3L;CXADR;NA;DEFB125;TREML4;KIF20A |
ASB6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB6 itself. We selected most functions ASB6 had, and list some proteins which have the same functions with ASB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IGF2R;SYNJ2BP;TGIF2LY;ECE2;SDCBP2;RXRG;BMF;WIF1;PTK2B |
ASB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB6.
FAM9B; L3MBTL3; RNF41; HSP90AB1; CUL5; RNF7; Dync1li1
- Q&As
- Reviews
Q&As (4)
Ask a questionThe molecular interactions involving ASB6 are not well-characterized. Identifying its binding partners or protein substrates would provide insights into its functional mechanisms.
The specific upstream regulators that modulate ASB6 expression have not been extensively investigated. Further studies are needed to identify the regulatory mechanisms involved.
Currently, ASB6 has not been identified as a diagnostic marker for any specific diseases or conditions. Further investigations may reveal its potential diagnostic applicability.
There is limited research on the role of ASB6 in cancer development. While some studies have suggested a possible involvement of ASB6 in certain types of cancer, additional research is required to establish a definitive link.
Customer Reviews (3)
Write a reviewIts high specificity and robust activity make it an ideal candidate for investigating intricate molecular interactions and elucidating complex biological mechanisms.
This variety allows me to select the most appropriate option based on the specific requirements of my research.
With its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.
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