asb7
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  • Official Full Name
  • ankyrin repeat and SOCS box containing 7
  • Background
  • The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
  • Synonyms
  • ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ankyrin repeat and SOCS box-containing 7
Cat.#:ASB7-896HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ASB7 protein, GST-tagged
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Cat.#:ASB7-2019MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ASB7 Protein
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Cat.#:ASB7-423RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ASB7 Protein, His-tagged
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Cat.#:ASB7-2000CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ASB7
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Cat.#:ASB7-12756ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ASB7
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Cat.#:ASB7-8660HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ASB7 293 Cell Lysate
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Involved Pathway

ASB7 involved in several pathways and played different roles in them. We selected most pathways ASB7 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
ASB18; RAP1GAP2; RNF144B; CD160; RAP1GAP2B; MGC174152; CD200R4; EGFR; FBXO3; ITPR2
Antigen processing: Ubiquitination &
UBE2U; LTN1; MKRN1; KLHL20; STUB1; LRR1; FBXO17; LRRC41; FBXO3; ASB4
Proteasome degradation
TRIM11; FBXO27; ASB6; UBR1; ASB4; HUWE1; ASB14; RNF182; UFL1; KLHL20
Class I MHC mediated antigen processing &
TRIM63; HUWE1; WSB1; UBE2L6; RNF25; ERAP2; TRIM41; FCGR1B; UBE2V2; RNF41
presentation
TRAF7; GAN; SEC61B; SH3RF1; RBCK1; SEC23A; SPSB1; ASB17; NPEPPS; VPRBP
Immune System
UBR1; TRIM3; CD300C; DHX9; STIM1B; CD300E; KIF22; CD200R2; TLR6; HUWE1

Protein Function

ASB7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB7 itself. We selected most functions ASB7 had, and list some proteins which have the same functions with ASB7. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein NONO; BORA; CHRD; MAPKAPK3; C19orf40; NEK8; KAT2A; COL6A2; FOSL1; CRYBA2

Interacting Protein

ASB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB7.
HMBOX1; CCDC136; CUL5; RNF7; ATF4

ASB7 Related Articles

Zhang, LF; Zhou, X; et al. Genome Wide Screening of Candidate Genes for Improving Piglet Birth Weight Using High and Low Estimated Breeding Value Populations. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 10:236-244(2014).
Baxter, SS; Carlson, LA; et al. Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 45:264-274(2009).