ASCL3
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Official Full Name
achaete-scute complex homolog 3
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Synonyms
ASCL3; achaete-scute complex homolog 3 (Drosophila); achaete scute complex (Drosophila) homolog like 3; achaete-scute homolog 3; bHLHa42; HASH3; Sgn1; ASH-3; bHLH transcriptional regulator Sgn-1; class A basic helix-loop-helix protein 42; bHLH transcripti;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ASCL3-902H | Recombinant Human ASCL3 protein, GST-tagged | Wheat Germ | GST | ||
Human | ASCL3-2818H | Recombinant Human ASCL3 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | ASCL3-3306H | Recombinant Human ASCL3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | ASCL3-1249HF | Recombinant Full Length Human ASCL3 Protein, GST-tagged | In Vitro Cell Free System | GST | 181 amino acids | |
Mouse | ASCL3-2027M | Recombinant Mouse ASCL3 Protein | Mammalian Cell | His | ||
Mouse | ASCL3-786M | Recombinant Mouse ASCL3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ASCL3-786M-B | Recombinant Mouse ASCL3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Ascl3-1741M | Recombinant Mouse Ascl3 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
- Involved Pathway
- Protein Function
- Interacting Protein
ASCL3 involved in several pathways and played different roles in them. We selected most pathways ASCL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ASCL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ASCL3 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASCL3 itself. We selected most functions ASCL3 had, and list some proteins which have the same functions with ASCL3. You can find most of the proteins on our site.
Function | Related Protein |
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DNA binding | MYC;ZFP319;H2AFB3;MLF1;TFAP2C;PROX1;ZFP775;ZFPM1;ISX |
RNA polymerase II regulatory region sequence-specific DNA binding | BCL6A;LEF1;NFIL3;TRP53;FOXF2;ZFP39;SP3;PCGF6;ZNF812 |
protein binding | NTRK3;TRAPPC2L;PRR3;TIPRL;AKTIP;TBX24;TBKBP1;PTPRZ1;TMEM110 |
protein dimerization activity | NEUROD6B;HER8.2;HER3;FIGLA;HES6;MXD4;SREBF1;ASCL3;MSC |
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | ETV3;NFKB1;ARHGAP35;FOXO3;CSDA;FERD3L;KLF6A;DMBX1;BCL6 |
ASCL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASCL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASCL3.
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, ASCL3 has been shown to play a role in embryonic development, particularly in the formation of the gastrointestinal tract.
ASCL3 expression and its dysregulation have been proposed as potential diagnostic markers for certain gastrointestinal diseases. However, further research is needed to establish its clinical utility.
ASCL3 acts as a transcription factor, binding to specific DNA sequences in the genome and regulating the expression of target genes involved in cellular differentiation and development.
Mutations or dysregulation of ASCL3 can lead to various gastrointestinal diseases, including colorectal cancer and inflammatory bowel diseases.
Yes, ASCL3 can interact with several other proteins to regulate its activity and downstream signaling pathways. Some known interacting proteins include β-catenin, SMAD4, and p300.
Customer Reviews (3)
Write a reviewChoosing the ASCL3 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.
The manufacturer's extensive experience and expertise in the field of ASCL3 protein research make them a trusted partner.
The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.
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