ash1l
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  • Official Full Name
  • ash1 (absent, small, or homeotic)-like
  • Background
  • This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.
  • Synonyms
  • ASH1L; ash1 (absent, small, or homeotic)-like (Drosophila); histone-lysine N-methyltransferase ASH1L; ASH1; ASH1L1; huASH1; KMT2H; ASH1-like protein; lysine N-methyltransferase 2H; absent small and homeotic disks protein 1 homolog; probable histone-lysine
Cat.#:ASH1L-30HTag:His/Flag
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATAD2, His&FLAG-tagged
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Cat.#:ASH1L-47HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human ASH1L protein, GST-tagged
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Cat.#:ASH1L-48HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human ASH1L protein, His-tagged
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Cat.#:ASH1L-49HTag:GST
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human ASH1L protein, GST-tagged
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Cat.#:ASH1L-50HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human ASH1L protein, His-tagged
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Cat.#:ASH1L-905HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ASH1L protein, GST-tagged
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Cat.#:ASH1L-2031MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ASH1L Protein
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Involved Pathway

ASH1L involved in several pathways and played different roles in them. We selected most pathways ASH1L participated on our site, such as Lysine degradation, Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASH1L were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysine degradation
SETDB2; EHHADH; ALDH3A2A; SETD8; C2orf34; SETD7; HYKK.2; SUV39H1A; SETDB1B; OGDHL
Tight junction
CLDN11A; PRKCBA; CLDN4; PARD6GB; MYL9B; CDC42; SMYHC1; MPP5; CLDN15A; PRKCBB

Protein Function

ASH1L has several biochemical functions, for example, DNA binding, chromatin binding, histone methyltransferase activity (H3-K36 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by ASH1L itself. We selected most functions ASH1L had, and list some proteins which have the same functions with ASH1L. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein HOXD3; SOX19A; POT1A; STAT2; EME1; ZFP335; THAP11; DHARMA; LHX1A; SMAD9
Function chromatin binding
Related Protein GLI2; JUB; C10orf119; BCL6; TFAM; TRIM24; PHF21A; FOS; UXT; ATXN7
Function histone methyltransferase activity (H3-K36 specific)
Related Protein SMYD2; SETMAR; SMYD2A; SMYD2B; SETD2; SETD3; ASH1L; NSD1
Function histone methyltransferase activity (H3-K4 specific)
Related Protein MLL5; ASH1L; WDR82; SMYD1B; SETMAR; KMT2E; WHSC1L1; WBP7; KMT2A; SETD3
Function zinc ion binding
Related Protein RBX1; CPZ; IFIH1; GATA2A; LMX1A; CAR1; DPF3; ADA; MT1X; POLR3K

Interacting Protein

ASH1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASH1L here. Most of them are supplied by our site. Hope this information will be useful for your research of ASH1L.
SMAD7; mtlA