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ATF7IP

Official Full Name

activating transcription factor 7 interacting protein
Overview

ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional;coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 (PubMed;19106100)).
Synonyms

ATF7IP; activating transcription factor 7 interacting protein; activating transcription factor 7-interacting protein 1; FLJ10688; p621; hAM; ATF-IP; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; MBD1-containing chromatin as;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	ATF7IP-8628HCL	Recombinant Human ATF7IP 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	ATF7IP-2071M	Recombinant Mouse ATF7IP Protein	Mammalian Cell	His	Inquiry
Mouse	ATF7IP-817M-B	Recombinant Mouse ATF7IP Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	ATF7IP-817M	Recombinant Mouse ATF7IP Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	ATF7IP-4798Z	Recombinant Zebrafish ATF7IP	Mammalian Cell	His	Inquiry
Chicken	ATF7IP-2041C	Recombinant Chicken ATF7IP	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
ATF7IP Related Articles

ATF7IP involved in several pathways and played different roles in them. We selected most pathways ATF7IP participated on our site, such as Chromatin modifying enzymes, Chromatin organization, PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATF7IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Chromatin modifying enzymes	MSL1;TADA3;SUZ12A;PHF21A;SAP30L;ING3;EPC1;PHF8;CHD4
Chromatin organization	ELP3;GATAD2A;VPS72;EPC1;GATAD2AB;EED;CSRP2BP;MBIP;KDM7AB
PKMTs methylate histone lysines	ATF7IP;SMYD3;AEBP2;RBBP5;SUZ12;SMYD2A;PRDM16;ASH2L;EED

ATF7IP has several biochemical functions, for example, ATPase activity, protein binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATF7IP itself. We selected most functions ATF7IP had, and list some proteins which have the same functions with ATF7IP. You can find most of the proteins on our site.

Function	Related Protein
ATPase activity	HSPA1B;HLTF;ATAD2;ABCB6;SMARCA4A;ATAD1B;SMARCA5;Abca2;KIF9
protein binding	MEIS1;HSPA1A;PFKM;TCHP;CDHR1;SPEG;ROBO2;HSPA12B;CFTR
transcription corepressor activity	RYBP;HIPK2;AEBP1;LHX9;TOB1;PRMT5;ASXL1;CREG1;CRYM

ATF7IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATF7IP here. Most of them are supplied by our site. Hope this information will be useful for your research of ATF7IP.

SMAD4; SP1; LAMA5; FLNB; STBD1; TFAP2A; COL4A2; LAMC1; NPR1; HLA-B; FLT4; MCAM; TTC3; CDH11; ACTB; RPS3A; ACTG1; PKD1; SPTBN1

Teramachi, J; Hiruma, Y; et al. Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease. JOURNAL OF BONE AND MINERAL RESEARCH 28:1489-1500(2013).

Cayado-Gutierrez, N; Moncalero, VL; et al. Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN. CELL STRESS & CHAPERONES 18:243-249(2013).