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ATG3

  • Official Full Name

    ATG3 autophagy related 3 homolog

  • Overview

    Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays;the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy;(Tanida et al., 2002 (PubMed 11825910)).
  • Synonyms

    ATG3; ATG3 autophagy related 3 homolog (S. cerevisiae); APG3 autophagy 3 like (S. cerevisiae) , APG3L; ubiquitin-like-conjugating enzyme ATG3; DKFZp564M1178; FLJ22125; MGC15201; PC3 96; hApg3; 2610016C12Rik; autophagy-related protein 3; APG3; APG3L; PC3-9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
  • N
  • T8
  • C
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATG3-744H Active Recombinant Human ATG3 Protein, His-tagged E.coli His
Human ATG3-35H Recombinant Human ATG3, His-tagged E.coli His
Human APG3L-678H Recombinant Human APG3L protein, GST-tagged Wheat Germ GST
Human ATG3-947H Recombinant Human ATG3 protein, GST-tagged Wheat Germ GST
Human ATG3-222H Recombinant Human ATG3, His-tagged E.coli His 1-314aa
Human ATG3-8625HCL Recombinant Human ATG3 293 Cell Lysate HEK293 N/A
Human ATG3-2564H Recombinant Human ATG3 protein, His-SUMO-tagged E.coli His-SUMO 1-314aa
Human ATG3-3031H Recombinant Human ATG3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ATG3-0070H Recombinant Human ATG3 Protein (Met1-Met314), N-His-tagged E.coli N-His Met1-Met314
Human DMABT-H17736 Mouse Anti-Atg3 Monoclonal Antibody Mouse N/A
Human ATG3-1065HFL Recombinant Full Length Human ATG3 Protein, C-Flag-tagged Mammalian cells Flag
Human ATG3-1816H Recombinant Human ATG3 protein, GST-tagged E.coli GST 1-314 aa
Human ATG3-1273HF Recombinant Full Length Human ATG3 Protein, GST-tagged In Vitro Cell Free System GST 314 amino acids
Human ATG3-396H Recombinant Human ATG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ATG3-396H-B Recombinant Human ATG3 Protein Pre-coupled Magnetic Beads HEK293
Human ATG3-0069H Recombinant Human ATG3 Protein (Met1-His287), N-T8 and C-His-tagged E.coli N-T8 and C-His Met1-His287
Mouse ATG3-2081M Recombinant Mouse ATG3 Protein Mammalian Cell His
Mouse ATG3-825M-B Recombinant Mouse ATG3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Atg3-1759M Recombinant Mouse Atg3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ATG3-825M Recombinant Mouse ATG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ATG3-844R Recombinant Rat ATG3 Protein Mammalian Cell His
Rat ATG3-500R Recombinant Rat ATG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ATG3-500R-B Recombinant Rat ATG3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATG3-440R Recombinant Rhesus monkey ATG3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATG3-269R Recombinant Rhesus Macaque ATG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ATG3-269R-B Recombinant Rhesus Macaque ATG3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ATG3-10381Z Recombinant Zebrafish ATG3 Mammalian Cell His
Chicken ATG3-5340C Recombinant Chicken ATG3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ATG3 Related Articles
  • ATG3 Related Research Area

ATG3 involved in several pathways and played different roles in them. We selected most pathways ATG3 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of autophagyIFNA2;GABARAPL2;INSB;Ifna15;IFNG;IFNA10;IFNG1-2;ATG3;ATG12

ATG3 has several biochemical functions, for example, Atg12 transferase activity, Atg8 ligase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG3 itself. We selected most functions ATG3 had, and list some proteins which have the same functions with ATG3. You can find most of the proteins on our site.

Function Related Protein
Atg12 transferase activityATG3;ATG10
Atg8 ligase activityATG3;ATG12
enzyme bindingRPS2;LGALS9;PIAS3;CPSF1;HSPA1B;YWHAE;PHB;USP22;UGT1A6A
ligase activityPIAS4;COP1;TRIM11;UBE3C;NHLRC1;TRIM41;UBE2L3B;TRIM28;RBBP6
protein bindingKIAA0101;EEF1G;SRSF5;IMP3;P2RX4;NXF1;TLR2;TFRC;MED12
ubiquitin-like protein transferase activityUBL4A;ATG3;RNF139;ATG16L1;RNF14;ARIH1

ATG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG3.

GABARAPL2; MAP1LC3B; GABARAP; ATG12

Kamat, PK; Kalani, A; et al. Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells. JOURNAL OF CELLULAR PHYSIOLOGY 230:378-394(2015).
Akl, MR; Ayoub, NM; et al. Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling. MARINE DRUGS 13:288-311(2015).
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