ATL1
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Official Full Name
atlastin GTPase 1
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Overview
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. -
Synonyms
ATL1; atlastin GTPase 1; spastic paraplegia 3A (autosomal dominant) , SPG3, SPG3A; atlastin-1; AD FSP; atlastin; FSP1; Atlastin1; Brain specific GTP binding protein; GBP3; SPG 3A; SPG3; GBP-3; hGBP3; GTP-binding protein 3; guanylate-binding protein 3; spastic paraplegia 3 protein A; brain-specific GTP-binding protein; guanine nucleotide-binding protein 3; HSN1D; SPG3A; AD-FSP;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Arabidopsis thaliana (Mouse-ear cress)
- Bos taurus (Bovine)
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Insect Cell
- Insect Cells
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ATL1-3333H | Recombinant Human ATL1 protein, GST-tagged | Insect Cells | GST | Met1-Thr447 | |
| Human | ATL1-9984H | Recombinant Human ATL1, GST-tagged | E.coli | GST | N-term-350a.a. | |
| Human | ATL1-669HCL | Recombinant Human ATL1 cell lysate | Insect Cell | N/A |
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| Human | ATL1-2943H | Recombinant Human ATL1 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | ATL1-1062H | Recombinant Human ATL1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | ATL1-2091M | Recombinant Mouse ATL1 Protein | Mammalian Cell | His |
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| Mouse | ATL1-832M-B | Recombinant Mouse ATL1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Atl1-1764M | Recombinant Mouse Atl1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | ATL1-832M | Recombinant Mouse ATL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | ATL1-848R | Recombinant Rat ATL1 Protein | Mammalian Cell | His |
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| Rat | ATL1-504R | Recombinant Rat ATL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | ATL1-504R-B | Recombinant Rat ATL1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Arabidopsis thaliana (Mouse-ear cress) | RFL79AF | Recombinant Full Length Arabidopsis Thaliana Ring-H2 Finger Protein Atl1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-381) |
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| Bos taurus (Bovine) | RFL34995BF | Recombinant Full Length Bovine Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Cynomolgus Monkey | ATL1-319C | Recombinant Cynomolgus ATL1 Protein, His-tagged | Mammalian Cell | His |
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| Cynomolgus Monkey | ATL1-69C | Recombinant Cynomolgus Monkey ATL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Cynomolgus Monkey | ATL1-69C-B | Recombinant Cynomolgus Monkey ATL1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Homo sapiens (Human) | RFL32288HF | Recombinant Full Length Human Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) | RFL18370MF | Recombinant Full Length Macaca Fascicularis Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Mus musculus (Mouse) | RFL20099MF | Recombinant Full Length Mouse Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL29280PF | Recombinant Full Length Pongo Abelii Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Rattus norvegicus (Rat) | RFL12079RF | Recombinant Full Length Rat Atlastin-1(Atl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-558) |
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| Rhesus Macaque | ATL1-445R | Recombinant Rhesus monkey ATL1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | ATL1-274R-B | Recombinant Rhesus Macaque ATL1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | ATL1-274R | Recombinant Rhesus Macaque ATL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | ATL1-7377Z | Recombinant Zebrafish ATL1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ATL1 Related Articles
ATL1 involved in several pathways and played different roles in them. We selected most pathways ATL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ATL1 has several biochemical functions, for example, GTP binding, GTPase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATL1 itself. We selected most functions ATL1 had, and list some proteins which have the same functions with ATL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | GNA12A;RAC1A;RAB19;RAB35;RHOT2;IIGP1;RHOB;GIMAP6;RERGLA |
| GTPase activity | GTPBP2;EIF5;RHOB;MXG;GNL3L;EIF5B;RHOT1B;RRAD;GBP6 |
| identical protein binding | GSTM3;TNK2;TOPBP1;MNS1;FBXW7;PRDX3;CCDC155;TPRGL;G6PDX |
| protein binding | FBN1;E2F2;PRAM1;POLH;ZBTB48;FAM98A;ITGA2;PPP1R2P3;TTC33 |
ATL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATL1.
TMED2; Rtn3; Reep5; Rtn4; RTN4; TMED10; TMED9
Peng, Y; Bo, L; et al. Interaction between antigen presenting cells and autoreactive T cells derived from BXSB mice with murine lupus. CELL RESEARCH 17:556-564(2007).
Han, SH; Li, B; et al. Isolation and functional analysis of autoreactive T cells from BXSB mice with murine lupus. JOURNAL OF AUTOIMMUNITY 19:45-54(2002).
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