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ABCA2

  • Official Full Name

    ATP-binding cassette, sub-family A (ABC1), member 2

  • Overview

    ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene.
  • Synonyms

    ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; ATP-binding cassette sub-family A member 2; OTTMUSP00000013051; ATP-binding cassette 2; ATP-binding cassette transporter 2; Abc2; AI413825; mKIAA1062; D2H0S1474E;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ABCA2-13H Recombinant Human ABCA2 protein, His-tagged E.coli His
Human ABCA2-032H Recombinant Human ABCA2 Protein, GST-tagged Wheat Germ GST
Mouse Abca2-12M Recombinant Mouse Abca2 protein, His-tagged E.coli His
Mouse Abca2-3729M Recombinant Mouse Abca2, His-tagged E.Coli or Yeast His 2434
Rat ABCA2-393R Recombinant Rat ABCA2 Protein Mammalian Cell His
Rat ABCA2-48R Recombinant Rat ABCA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ABCA2-48R-B Recombinant Rat ABCA2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ABCA2 involved in several pathways and played different roles in them. We selected most pathways ABCA2 participated on our site, such as ABC transporters, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ABC transportersABCB3L1;ABCD2;ABCB7;Abcb1b;ABCB5;ABCA4;TAP1;ABCD4;ABCD3A
LysosomeSLC11A2;NAGLU;ACP5;ATP6V0A1;ATP6V0B;Abca2;PPT2;NPC2;ACP5A

ABCA2 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA2 itself. We selected most functions ABCA2 had, and list some proteins which have the same functions with ABCA2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingITPK1A;CARKD;AXL;CAMKK1A;ENTPD1;ADCK2;DNAJA3B;SYK;IRAK1
ATPase activityHAND2;TOR1A;PSMD6;KIF7;ABCG4B;SWSAP1;KIF15;KIF20A;ERCC3
ATPase activity, coupled to transmembrane movement of substancesABCA4;ABCG3;ABCB8;ABCD1;ABCG2D;ABCB10;ABCC12;IPO8;SFRP5
nucleotide bindingARL15A;SBK3;RPS6KAL;ATP1A1A.2;DDX19;SFRS3A;TUBA8L2;HSPA12A;KIF5AA
transporter activityFABP2;SLC37A4;AP1G1;TTPAL;SLC12A3;LCN12;CPNE7;RBP2B;ATP5O

ABCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA2.

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Where is ABCA2 protein most expressed? 04/14/2023

ABCA2 is most highly expressed in the fetal and adult brain, spinal cord, ovaries and leukocytes.

What is the function of ABCA2? 04/14/2023

It may be a lipid transporter that modulates cholesterol sequestration in late endosomes/lysosomes. ABCA2 regulates the production of amyloid-beta by modulating the activation of signaling pathways that regulate the transcription of amyloid precursor proteins by regulating sphingolipid metabolism or by its role in the γ-secretase processing of APP. And it may play a role in myelin formation.

There is no recombinant ABCA2 protein in your catalog that meets my needs, is it possible to customize it? 04/14/2023

Sure, Creative BioMart supports custom protein production services.

What tag does your recombinant ABCA2 protein use? 04/14/2023

To improve the solubility and facilitate the subsequent experimental operation, our ABCA2 protein products use GST or His tags for your choice.

Which expression system does Creative BioMart's recombinant ABCA2 protein use? 04/14/2023

We offer a variety of expression systems, including E. coli, Yeast, Wheat Germ, and Mammalian Cell expression systems.

What species-derived recombinant ABCA2 proteins does your company offer? 04/14/2023

Creative BioMart offers recombinant ABCA2 proteins of several species, including human, mouse, and rat.

How to ensure that the recombinant protein reaches the customer safely and quickly? 04/14/2023

We will ensure the safety of the products on the road by putting them in ice bags or additional packaging outside the package according to the characteristics of the products.

Can I get a discount on the price? 04/14/2023

Discounts are available for first-time purchases and for holidays. For specific promotions, please contact our customer service staff. Thank you for your inquiry and we look forward to your order.

What is the tissue specificity of ABCA2 protein? 04/14/2023

ABCA2 is enriched in brain tissue and may play a role in neural development.

What is the full name of ABCA2? 04/14/2023

ATP binding cassette subfamily A member 2, and this protein is a member of the superfamily of ATP-binding cassette (ABC) transporters.

Customer Reviews (3)

Write a review
Reviews
09/15/2022

    I purchased the Abca2 recombinant protein and the quality is excellent, saving me weeks of research time.

    05/08/2021

      Customer service representatives have provided valuable assistance in helping to decide which products best meet our research needs.

      01/16/2020

        Creative BioMart's customer service is excellent, friendly and efficient, making it a worthwhile long-term partner.

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