ABCA5
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Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 5
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Overview
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. -
Synonyms
ABCA5; ATP-binding cassette, sub-family A (ABC1), member 5; ATP-binding cassette sub-family A member 5; EST90625; ATP-binding cassette A5; ABC13; FLJ16381; DKFZp451F117; DKFZp779N2435;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Mouse | Abca5-8139M | Recombinant Mouse Abca5 protein, His & T7-tagged | E.coli | His/T7 | Val1401~Phe1642 (Accession # Q8K448) |
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| Rat | ABCA5-394R | Recombinant Rat ABCA5 Protein | Mammalian Cell | His |
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| Rat | ABCA5-49R-B | Recombinant Rat ABCA5 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | ABCA5-49R | Recombinant Rat ABCA5 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | ABCA5-5744Z | Recombinant Zebrafish ABCA5 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ABCA5 Related Articles
ABCA5 involved in several pathways and played different roles in them. We selected most pathways ABCA5 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCC1;ABCD4;ABCC3;SUR2A;Abca2;ABCC8;ABCB5;ABCB1A;ABCC5 |
ABCA5 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA5 itself. We selected most functions ABCA5 had, and list some proteins which have the same functions with ABCA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | MYHZ1.2;AK9;EPHA4B;ZRANB3;MOV10;EPHB4A;CDK13;IARS2;DCLK2 |
| ATPase activity | ABCE1;WRN;KIF12;ABCC1;ABCA6;DNAH5;MLH1;CENPE;PSMC6 |
| ATPase activity, coupled to transmembrane movement of substances | ABCC12;ABCD4;ABCB10;ABCA1B;ABCD3A;ABCG2;ABCB6A;ABCC5;ABCA5 |
| nucleotide binding | CLCN4-2;SIK2A;NLRP4C;ATAD5B;RBMY1F;HDGF;HHAT;RBM4B;SRSF2 |
| transporter activity | AQP1A.1;AQP8A.1;HIAT1;ASNA1;CSN2;MUP17;AP3B2;ATP5D;LCN12 |
ABCA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA5.
- Q&As
- Reviews
Q&As (10)
Ask a questionYes, our recombinant ABCA5 proteins can be used as a variety of downstream applications based on the antigen-antibody reaction.
Creative BioMart provides coupons for each new customer and runs promotions on holidays. For specific promotions, please contact our sales staff for more information.
The ABCA5 protein encoded by abca5 (EST90625), which is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known.
The ABCA5 protein is low tissue specificity.
ABCA5 protein has the molecular function of translocase and may play a role in the processing of autolysosomes.
ABCA5 is a cholesterol efflux transporter in macrophages, responsible for the formation of APOAI/ high-density lipoprotein (HDL) in the plasma membrane under high cholesterol levels and involved in the reverse transport of cholesterol.
Yes, our scientists will help you choose the suitable expression system according to your research needs.
We currently offer recombinant ABCA5 proteins from species such as zebrafish, mouse and rat. If you have additional needs, please contact our experts to produce custom recombinant proteins.
We provide MSDS documents and data sheets with detailed product information.
To improve the protein solubility and facilitate downstream applications, our recombinant ABCA5 proteins use His tags. Moreover, we can choose appropriate tags for you according to your research requirements.
Customer Reviews (3)
Write a reviewThe technical support experts at Creative BioMart customized ABCA5 protein with a specific fusion tag for me.
ABCA5 proteins are of high purity and good quality, and will be repurchased later.
I used your recombinant ABCA5 protein in Western Blot experiments and the results were very satisfactory.
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