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ABCC8

  • Official Full Name

    ATP-binding cassette, sub-family C (CFTR/MRP), member 8

  • Overview

    The protein encoded by the SUR1 gene is a member of the superfamily of ATP-binding cassette . No disease has been associated with this gene thus far.
  • Synonyms

    ABCC8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; sulfonylurea receptor; Sur; SUR1; D930031B21Rik;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ABCC8-8122H Recombinant Human ABCC8 protein, His & T7-tagged E.coli His/T7 Val679~Thr929 (Accession # Q09428)
Human ABCC8-053H Recombinant Human ABCC8 Protein, GST-Tagged Wheat Germ GST
Human ABCC8-238H Recombinant Human ABCC8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ABCC8-2934H Recombinant Human ABCC8 protein, His-tagged E.coli His 610 - 769 aa
Human ABCC8-5866H Recombinant Human ABCC8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ABCC8-592H Recombinant Human ABCC8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human ABCC8-243H Recombinant Human ABCC8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ABCC8-243H-B Recombinant Human ABCC8 Protein Pre-coupled Magnetic Beads HEK293
Human ABCC8-301376H Recombinant Human ABCC8 protein, GST-tagged E.coli GST Met610-Val769
Human ABCC8-811HFL Recombinant Full Length Human ABCC8 Protein, C-Flag-tagged Mammalian cells Flag
Human ABCC8-0606H Recombinant Human ABCC8 Protein (Val679-Thr929), N-His-tagged E.coli N-His Val679-Thr929
Mouse Abcc8-1460M Recombinant Mouse Abcc8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ABCC8-408R Recombinant Rat ABCC8 Protein Mammalian Cell His
Rat ABCC8-63R-B Recombinant Rat ABCC8 Protein Pre-coupled Magnetic Beads HEK293
Rat ABCC8-63R Recombinant Rat ABCC8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ABCC8-7696Z Recombinant Zebrafish ABCC8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ABCC8 Related Articles

ABCC8 involved in several pathways and played different roles in them. We selected most pathways ABCC8 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ABC transportersABCB9;ABCB6A;ABCC3;ABCA4;ABCA6;ABCA7;ABCB10;ABCC8;ABCD2

ABCC8 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC8 itself. We selected most functions ABCC8 had, and list some proteins which have the same functions with ABCC8. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCKMT1B;NME2B.2;UBE2QL1;AFG3L2;STK24B;SCYL3;PTK2AB;SLKA;AKT2L
ATPase activityBLM;HLTF;VCP;ABCG3;HSPA5;ABCG5;VWA8;KIF25;ABCD3B
ATPase activity, coupled to transmembrane movement of substancesABCA9;ABCD3;DPY19L2;ABCA4A;ABCC1;ABCB7;IPO8;ABCC8;ABCA3
nucleotide bindingRAVER2;KIF4;LACE1B;EPHA4B;ZNF143B;RBM12B2;CLK2A;GLULB;GNA15.1
sulfonylurea receptor activityABCC9;ABCC8

ABCC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC8.

Alves, C; Constanca, J; et al. A novel atypical presentation of insulin autoimmune syndrome (Hirata's disease) in a child. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 26:1163-1166(2013).
Irgens, HU; Molnes, J; et al. Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry. DIABETOLOGIA 56:1512-1519(2013).
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