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ABP1

  • Official Full Name

    amiloride binding protein 1 (amine oxidase (copper-containing))

  • Overview

    This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
  • Synonyms

    ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-sensitive amine oxidase [copper-containing]; AOC1; DAO; ABP; ABP1_HUMAN; Amiloride binding protein 1 (amine oxidase (copper containing)); Amiloride binding protein 1; Amiloride binding protein; Amiloride sensitive amine oxidase; Amiloride-binding protein; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase; amiloride-binding protein-1; amiloride-sensitive amine oxidase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Maize
  • Rat
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293F
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ABP1-112H Recombinant Human ABP1 Protein, GST-Tagged Wheat Germ GST
Human ABP1-9255H Recombinant Human ABP1, GST-tagged E.coli GST 400-751a.a.
Human ABP1-3409H Recombinant Human ABP1, His-tagged E.Coli or Yeast His 751
Human ABP1-113H Recombinant Human ABP1 Protein, GST-Tagged Wheat Germ GST
Human ABP1-114H Recombinant Human ABP1 Protein, GST-Tagged Wheat Germ GST
Human ABP1-9123HCL Recombinant Human ABP1 293 Cell Lysate HEK293 N/A
Human ABP1-15H Recombinant Human ABP1 Protein, His-tagged HEK293F N-His Glu20-Val751
Human ABP1-834HF Recombinant Full Length Human ABP1 Protein, GST-tagged In Vitro Cell Free System GST 751 amino acids
Human ABP1-16H Recombinant Human ABP1 Protein, His-tagged E.coli N-His Thr400-Val751
Human ABP1-832HF Recombinant Full Length Human ABP1 Protein, GST-tagged In Vitro Cell Free System GST 751 amino acids
Rat Abp1-3410R Recombinant Rat Abp1, His-tagged E.Coli or Yeast His 746
Maize ABP1-3862M Recombinant Maize ABP1 protein, His-tagged E.coli His 39-201aa
Maize ABP1-1265M Recombinant Maize ABP1 Protein (39-201 aa), His-tagged E.coli His 39-201 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ABP1 Related Articles

ABP1 involved in several pathways and played different roles in them. We selected most pathways ABP1 participated on our site, such as Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arginine and proline metabolismLAP3;P4HA1;CKMT1A;AGMAT;ALDH7A1;DAO.3;GATM;DAO.2;CNDP2
Histidine metabolismABP1;MAOB;ALDH3B1;ALDH9A1B;FTCD;AOC1;HAL;CNDP1;ALDH2.1
Tryptophan metabolismTDO2;CAT;AOX1;AANAT1;ALDH3A2;AOX4;DHCR24;ALDH9A1;HADHA
Metabolic pathwaysMTHFR;TH;KLF15;PLCD3A;CBSA;AOX1;PPT1;ACSM2B;DHRS13L1

ABP1 has several biochemical functions, for example, calcium ion binding, copper ion binding, diamine oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABP1 itself. We selected most functions ABP1 had, and list some proteins which have the same functions with ABP1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingEMR3;PLA2G12B;PCDH8;PLA2G4B;S100A16;ANXA3B;CUBN;CIB3;SULF2A
copper ion bindingMT1;HAMP;AOC2;LOXL3;MOXD2;AOC3;HEPHL1;TYRP1;LOXL2
diamine oxidase activity
drug bindingDHFR;HMGCS1;P2RX2;HTR2C;FASN;CHRNA3;DHODH;SETD6;TOP2A
heparin bindingMMP7;HDGF;ADAMTSL5;SLIT1B;SLIT1A;SMOC2;GREM2;SLIT2;MSTN
histamine oxidase activity
methylputrescine oxidase activity
primary amine oxidase activityMAOA;AOC3;MAOB;AOC2;AOC1;ABP1;VCAM1
propane-1,3-diamine oxidase activity
protein complex bindingDRD1;GNB4;MYC;MLKL;PAFAH1B1;NR0B2;MYO7A;NOG;RAP1B
protein homodimerization activityPAFAH1B1;LGALS6;PRDX4;TDG;CD247;CECR1;SOD1;RAP1GAP;AXIN1
quinone bindingVKORC1L1;AOC2;VKORC1;AOC3;CBR4;NDUFS7;TP53I3;ABP1;ETFDH
receptor activityNCR3;GRIA3B;THRAP3;MCC;GFRA1B;LILRB2;CADM4;PAQR5B;CD1D
zinc ion bindingSLU7;RABIF;FBXO11;RNF115;AGTPBP1;RXRBB;MORC3A;SAMHD1;CHORDC1

ABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABP1.

Grandits, M; Oostenbrink, C; et al. Molecular dynamics simulations of the auxin-binding protein 1 in complex with indole-3-acetic acid and naphthalen-1-acetic acid. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:2744-2755(2014).
Seeley-Fallen, MK; Liu, LJ; et al. Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:9881-9886(2014).
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