ACP1
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Official Full Name
acid phosphatase 1, soluble
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Overview
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
ACP1; acid phosphatase 1, soluble; low molecular weight phosphotyrosine protein phosphatase; LMW-PTP; LMW-PTPase; adipocyte acid phosphatase; red cell acid phosphatase 1; protein tyrosine phosphatase; acid phosphatase of erythrocyte; cytoplasmic phosphoty;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- His
- GST
- Myc
- DDK
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- ACP1 Related Articles
- ACP1 Related Research Area
ACP1 involved in several pathways and played different roles in them. We selected most pathways ACP1 participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junction | FYN;ACTB1;NLK;FGFR1;ACTN2B;TCF7;BAIAP2;INSRA;MET |
ACP1 has several biochemical functions, for example, acid phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACP1 itself. We selected most functions ACP1 had, and list some proteins which have the same functions with ACP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acid phosphatase activity | ACP6;MINPP1A;ACPT;MINPP1B;ACP5A;ACP5B;ACPL2;PXYLP1;ACP1 |
| non-membrane spanning protein tyrosine phosphatase activity | PTPN11;PTPN4;PTPN12;DUSP1;ACP1;PTPN18;PTPN9 |
| protein binding | CNOT4;HTN1;ASNS;C11orf49;GRAP2;CCDC13;TNNT1;TSC2;NRAP |
ACP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACP1.
EIF1B; NR3C1; EPB41; VHL; EIF6; PAK2; IKBKE; TNIK; FNBP1L; MRPL20; SFMBT1; US3; VCAM1; p27958-pro_0000037566
- Q&As
- Reviews
Q&As (10)
Ask a questionF and S.
Through the polymerase chain reaction-resreiction fragment length polymorphism.
Esophageal cancer, gastric cancer and gastrointestinal cancer will lead to up-regulation of ACP1 expression, while colorectal cancer will reduce it.
Because ACP1 has low dephosphorylation effect on insulin receptor.
To adjust the level of FMN and flavin adenine dinucleotide.
Immunohistochemical staining observation of two related protein sections.
Three.
The cholesterol biosynthesis, neutotransmitter synthesis and it links to behavioral and cellular response to stress via p190RhoGAP
The PBS conraining 10% goat serum.
The TPH2, DDC and GAD1.
Customer Reviews (3)
Write a reviewThe answers are very concise.
There are all the questions I want to know.
The answer was very patient.
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