ACSS1
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Official Full Name
acyl-CoA synthetase short-chain family member 1
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Overview
Cytoplasmic acetyl-CoA synthetase (AceCS1) catalyzes the conversion of acetate and CoA to acetyl-CoA (1, 2). Acetyl-CoA synthesized by AceCS1 is used for fatty acid and lipid biosynthesis (1, 2). Studies suggest that this enzyme is regulated by sterol reg -
Synonyms
ACSS1; acyl-CoA synthetase short-chain family member 1; ACAS2L, acetyl Coenzyme A synthetase 2 (AMP forming) like; acetyl-coenzyme A synthetase 2-like, mitochondrial; AceCS2L; dJ568C11.3; MGC33843; acetate--CoA ligase 2; ACAS2L; ACECS1; FLJ45659;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- ACSS1 Related Articles
ACSS1 involved in several pathways and played different roles in them. We selected most pathways ACSS1 participated on our site, such as Glycolysis / Gluconeogenesis, Pyruvate metabolism, Propanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycolysis / Gluconeogenesis | MINPP1A;PGM1;PKMA;GAPDH;ALDH9A1B;ENO2;GALM;ALDH3A2;PFKM |
| Pyruvate metabolism | ACACB;SLC16A1;ME1;ACYP1;ACOT12;ACSS2;ALDH9A1;PKMB;PDHA2 |
| Propanoate metabolism | PCCA;ACACA;ACACB;HADHAB;ACSS3;PCCB;LDHAL6B;HADHAA;SUCLA2 |
| Metabolic pathways | ALDH3A2A;MPI;PLCB3;B4GALT3;SRM;ATP5G1;ADSS;B4GALT1;UGT2A2 |
| Carbon metabolism | ALDOCB;ENO1;GPT;HAO2;HK3;ESD;GLUD1;ANI_1_2390104;HK2 |
ACSS1 has several biochemical functions, for example, AMP binding, ATP binding, acetate-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSS1 itself. We selected most functions ACSS1 had, and list some proteins which have the same functions with ACSS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| AMP binding | APRT;PYGL;PRKAG1;FBP1;PYGM;CYB5R3;PRPS1;ACSS2;PRPS2 |
| ATP binding | GLUD1;MYLK3;MAP2K4;ENTPD3;DCLK1;PRKCBB;CKMT1A;RBM4.3;DARS2 |
| acetate-CoA ligase activity | ACSS2;ACSS3;ACSS1 |
| protein binding | PSG5;NDNL2;APC;PODXL;NFATC3;GOLGA2;MTNR1B;SP140;ZNF843 |
ACSS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSS1.
VAC14; CLPP
- Q&As
- Reviews
Q&As (10)
Ask a questionACSS1 protein expression is regulated by a variety of factors including nutrient availability, hypoxia, and oncogenic signaling pathways.
ACSS1 protein has been implicated in the regulation of inflammatory gene expression and the production of pro-inflammatory cytokines.
ACSS1 protein is involved in the acetylation of histones, which can regulate gene expression by modulating chromatin structure.
Inhibition of ACSS1 protein activity has been shown to impair cancer cell growth and induce cell death in vitro and in vivo.
ACSS1 protein has been implicated in the regulation of insulin signaling and glucose metabolism in response to insulin.
ACSS1 protein expression is upregulated in many cancer cells as part of the Warburg effect, which is a metabolic adaptation that allows cancer cells to produce energy through glycolysis.
ACSS1 protein has been implicated in the regulation of autophagy, a cellular process that degrades and recycles cellular components.
ACSS1 protein is expressed in the brain and has been implicated in the regulation of neuronal function and synaptic plasticity.
ACSS1 protein is required for the differentiation of adipocytes and the storage of triglycerides in adipose tissue.
ACSS1 protein plays a critical role in linking glucose metabolism to fatty acid synthesis in the cytosol of mammalian cells.
Customer Reviews (5)
Write a reviewWow, this protein is like a superhero in our lab! It saves us time and effort while delivering top-notch performance.
We've been using this protein for protein-protein interaction studies, and it has exceeded our expectations. It exhibits strong and specific binding with our target.
Exceptional customer service that ensures a smooth experience. Quality protein that delivers results.
This product has significantly accelerated our research progress. Its high activity and excellent functionality have allowed us to obtain meaningful data faster.
I'm just blown away by the awesomeness of this protein! It's like having a trusted lab buddy that never lets you down. Love it!
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