Activin A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | Activin A-17H | Active Recombinant Human Activin A protein | Insect Cell | N/A | 116 amino acid residues. | |
Human | Activin A-15H | Active Recombinant Human Activin A, His-tagged | Nicotiana | His | ||
Human | Activin A-57H | Active Recombinant Human Activin A, CF | CHO | N/A | ||
Human | Activin A-01HG | Active GMP Recombinant Human Activin A Protein | CHO-K1 | |||
Human | Activin A-16H | Recombinant Human Activin A protein, His-tagged | E.coli | His |
- Activin A Related Research Area
Activin A involved in several pathways and played different roles in them. We selected most pathways Activin A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Activin A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Activin A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Activin A itself. We selected most functions Activin A had, and list some proteins which have the same functions with Activin A. You can find most of the proteins on our site.
Function | Related Protein |
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Activin A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Activin A here. Most of them are supplied by our site. Hope this information will be useful for your research of Activin A.
- Q&As
- Reviews
Q&As (21)
Ask a questionActivin A has the ability to modulate miRNA expression in PCa cell lines, suggesting a potential relationship between miRNA expression and downstream target genes.
Serum activin A levels can be measured using immunoassay techniques, such as enzyme-linked immunosorbent assays (ELISA) or radioimmunoassays (RIA).
Activin A increases the expression of activin type IIA receptor on CD8+ T cells and CD19+ B cells in Kawasaki disease.
The association suggests that activin A may play a role in the inflammatory and remodeling processes in SRA (systemic rheumatic autoimmune diseases).
While myostatin is not overproduced in CKD, suggesting impaired renal clearance, activin A is overproduced in the kidney and heart.
The association between enhanced serum activin A levels and the incidence of DD and development of HF suggests that activin A may serve as a potential biomarker for these conditions.
Myostatin and activin A negatively regulate muscle metabolism and growth by promoting muscle wasting and inhibiting muscle protein synthesis.
Based on their role in muscle wasting, myostatin and activin A may be potential therapeutic targets for addressing muscle loss in CKD.
Activin A is implicated in myocardial fibrosis, indicating its potential involvement in the pathological remodeling of heart tissue.
Activin A has been shown to be involved in the pathogenesis of CCl4-induced acute liver injury.
In CKD, both myostatin and activin A plasma concentrations are increased.
ncreased myostatin and activin A plasma concentrations in CKD can contribute to muscle wasting and further impair muscle function and strength.
Activin A is involved in the inflammatory response, suggesting its contribution to the regulation of immune and inflammatory processes.
The proposal suggests adding myostatin and activin A to the list of uremic toxins, indicating their potential role in CKD-related complications.
Yes, enhanced serum activin A levels are associated with the incidence of DD (diastolic dysfunction) and the development of HF (heart failure).
Myostatin and activin A activate the ubiquitin proteasome system, leading to increased protein degradation, and inhibit the Akt/mTOR pathway, which negatively affects muscle protein synthesis.
Blocking the actions of activin A is proposed as a potential therapeutic approach for acute liver injury.
Targeting activin A could potentially have therapeutic implications for mitigating the inflammatory response and reducing myocardial fibrosis, although further research is needed to explore this possibility.
The involvement of activin A in myocardial fibrosis suggests that it may play a role in the pathological accumulation of fibrous tissue in the heart.
Activin A suppresses the expression of CD25, CD69, and activin type IIA receptors on peripheral CD8+ T lymphocytes, thereby reducing their activity.
Myostatin and activin A induce muscle wasting by activating the ubiquitin proteasome system, which leads to protein degradation, and by inhibiting the Akt/mammalian target of rapamycin (mTOR) pathway, which hinders muscle protein synthesis.
Customer Reviews (5)
Write a reviewThe protein product maintains remarkable consistency in its physical and biochemical properties, such as molecular weight, solubility, and activity, across multiple production lots.
The protein product is shipped promptly, and we have consistently received our orders within the expected timeframe.
The protein product exhibits exceptional purity, confirmed by rigorous analytical testing methods such as SDS-PAGE and mass spectrometry.
In our experiments, the protein product consistently demonstrates potent and specific binding to its target, leading to robust biological effects.
The company's customer support team is responsive, knowledgeable, and readily addresses any technical or scientific questions we have regarding the protein product.
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