ADAMTS1
-
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 1
-
Overview
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; C3-C5; METH1; A disintegrin and metalloproteinase with thrombospondin motifs 1; METH-1; ADAM-TS1; ADAMTS-1; ADAM-TS 1; human metalloproteinase with thrombospondin type 1 motifs; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- CHO
- E.coli
- HEK293
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Involved Pathway
- Protein Function
- Interacting Protein
- ADAMTS1 Related Articles
- ADAMTS1 Related Research Area
ADAMTS1 involved in several pathways and played different roles in them. We selected most pathways ADAMTS1 participated on our site, such as Degradation of the extracellular matrix, Endochondral Ossification, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Degradation of the extracellular matrix | CAPNS1;MGC174857;FAM49BA;TPSAB1;MMP11;FURINA;BMP1A;CTSL2;COL15A1B |
Endochondral Ossification | DDR2;IFT88;ADAMTS4;NKX3-2;CTSL2;PTH;CDKN1C;ADAMTS1;PTHLH |
Extracellular matrix organization | COL9A3;ADAMTS5;MATN1;LAMB1B;CTSB;COL13A1;PRP;MMP19;MMP15 |
Metabolism of proteins | EIF5;PAPPA2;TRAPPC10;PFDN2;INHBAA;F9B;MUC1;WIPI1;MPDU1A |
O-glycosylation of TSR domain-containing proteins | ADAMTS1;C8orf84;ADAMTS20;ADAMTS18;ADAMTSL4;ADAMTS8;ADAMTSL5;ADAMTSL1;THSD1 |
O-linked glycosylation | MUC15;MUCL1;SPON1A;GCNT3;ADAMTS8;THSD7A;ST6GALNAC2;MUC1;SPON1 |
Post-translational protein modification | GCNT3;CBX4;NAPG;EIF5A2;ALG10B;SENP5;STT3A;DAD1;DPAGT1 |
ADAMTS1 has several biochemical functions, for example, heparin binding, metalloendopeptidase activity, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS1 itself. We selected most functions ADAMTS1 had, and list some proteins which have the same functions with ADAMTS1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
heparin binding | WISP3;Epy;CFH;FGF2;FGF10;CCL8;LIPG;CHRD;ELANE |
metalloendopeptidase activity | XRCC6BP1;MMP20;MIPEP;MMP23B;PHEX;ADAM10A;ADAM7;ADAM8A;MEP1A |
metallopeptidase activity | ADAM12;GM12824;NAALAD2;HE2;MMP1A;MEP1A.2;MMP13A;ADAM23;C6AST4 |
zinc ion binding | PRICKLE1A;TRIM71;HERC2;LMO4;SYTL4;NEURL1AB;ADAM15;FTR43;SPRYD5 |
ADAMTS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS1.
USP17L24; trpE
- Q&As
- Reviews
Q&As (11)
Ask a questionPro-peptide, metallo proteinase, depolymerase/cysteine enriched region, spacer region and thrombospondin type I repeat.
Yes, you can first communicate with our experts for customized requirements.
The delivery cycle of this kind of protein is related to your specific customization requirements, you can communicate with our experts first.
We can provide ADAMTS1 protein fused with other tags.
ADAMTS1 applied to a variety of diseases including colon, oesophageal and lung cancers.
ADAMTS1 is involved in the physiological and pathological processes of human growth and development, the formation of the urinary and reproductive systems, and the development of tumours in tissues and organs.
Inactivation of ADAMTS1 causes infertility and developmental delay in females.
Yes, all ADAMTS1 proteins are currently discounted.
ADAMTS1 degrades extracellular matrix proteins such as versican , aggrecan , syndecan and nidogen.
Yes, our team can customize the protein according to your requirements.
Trehalose can prevent protein secondary structure changes, elongation and aggregation during freeze-drying.
Customer Reviews (3)
Write a reviewExcellent after-sales service, solving many experimental problems.
The products provided by your company are inexpensive and of high quality, and because of this, my experiments could be completed successfully.
The price of the product is right and the quality meets my research needs.
Ask a Question for All ADAMTS1 Products
Required fields are marked with *
My Review for All ADAMTS1 Products
Required fields are marked with *