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ADC

  • Official Full Name

    arginine decarboxylase

  • Overview

    Arginine decarboxylase is an enzyme that in humans is encoded by the ADC gene.
  • Synonyms

    ADC; arginine decarboxylase; KIAA1945; ODC p; ODC1L; ornithine decarboxylase like; L-Arginine carboxy lyase; ODC paralog; ODCp; ARGDC; ODC-paralogue; antizyme inhibitor 2; ODC antizyme inhibitor-2; ornithine decarboxylase-paralog; ornithine decarboxylase-like protein; AZI2; ODC-p;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADC-319H Recombinant Human ADC Protein, GST-tagged Wheat Germ GST
Human ADC-9403H Recombinant Human ADC, GST-tagged E.coli GST 251-460a.a.
Human ADC-901HF Recombinant Full Length Human ADC Protein, GST-tagged In Vitro Cell Free System GST 460 amino acids
Chicken ADC-5591C Recombinant Chicken ADC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADC Related Articles

ADC involved in several pathways and played different roles in them. We selected most pathways ADC participated on our site, such as Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arginine and proline metabolismMAOA;AZIN2;PRODH;P4HA1A;P4HA1B;HOGA1;SAT1;ALDH2;ALDH9A1
Metabolic pathwaysGALM;AK1;AOX4;HADHB;IMPDH2;IDO1;TST;UMPS;B3GAT3

ADC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ADC itself. We selected most functions ADC had, and list some proteins which have the same functions with ADC. You can find most of the proteins on our site.

Function Related Protein

ADC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADC here. Most of them are supplied by our site. Hope this information will be useful for your research of ADC.

Priola, AM; Priola, SM; et al. Chemical-Shift and Diffusion-Weighted Magnetic Resonance Imaging of Thymus in Myasthenia Gravis Usefulness of Quantitative Assessment. INVESTIGATIVE RADIOLOGY 50:228-238(2015).
Verma, VA; Pillow, TH; et al. The cryptophycins as potent payloads for antibody drug conjugates. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 25:864-868(2015).
  • Q&As
  • Reviews

Q&As (12)

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How does ADC protein-based immunotherapy work in the body? 12/12/2022

ADC protein-based immunotherapy works by using a targeted approach to deliver a potent cytotoxic drug directly to cancer cells while sparing healthy cells. The ADC protein is designed to recognize and bind to specific antigens expressed on the surface of cancer cells. Once bound, the ADC protein is internalized by the cancer cell and the cytotoxic drug is released, causing damage to the cancer cell and eventually leading to cell death.

How effective is ADC protein-based immunotherapy? 10/04/2022

The effectiveness of ADC protein-based immunotherapy can vary depending on the specific type of cancer being treated, the patient's individual cancer profile, and the characteristics of the ADC protein being used. However, some studies have shown significant improvement in overall survival and disease progression in patients treated with ADC protein-based immunotherapy compared to traditional cancer treatments alone. Further research is needed to fully assess the potential of ADC protein-based immunotherapy as a viable treatment option for cancer.

How is ADC protein-based immunotherapy administered? 04/13/2020

ADC protein-based immunotherapy is typically administered through an intravenous infusion, meaning that the treatment is delivered directly into the patient's bloodstream. The treatment may be administered on an outpatient basis, or the patient may need to stay in the hospital for monitoring during their initial treatment.

How long does ADC protein-based immunotherapy last? 01/12/2020

The duration of ADC protein-based immunotherapy can vary depending on the individual patient and the specific type of ADC protein being used. Some patients may require multiple cycles of treatment over the course of several months or years. The treatment schedule is typically determined based on the patient's response to treatment and the likelihood of disease recurrence.

What are the potential side effects of ADC protein-based immunotherapy? 05/31/2019

ADC protein-based immunotherapy may cause a range of side effects, including fever, chills, fatigue, nausea, vomiting, and diarrhea. More serious side effects may include heart problems, liver damage, and bleeding disorders. However, the specific side effects of ADC protein-based immunotherapy can vary depending on the individual patient and the specific type of ADC protein being used.

Can ADC protein-based immunotherapy be used in combination with other cancer treatments? 06/18/2018

Yes, ADC protein-based immunotherapy can be used in combination with other cancer treatments such as chemotherapy and radiation therapy. Combination therapy can potentially produce better treatment outcomes than monotherapy alone.

How is the ADC protein designed and developed? 03/27/2018

The ADC protein is typically designed using a combination of monoclonal antibodies and cytotoxic agents. The monoclonal antibody portion of the ADC protein is engineered to recognize and bind to specific antigens expressed on cancer cells. The cytotoxic agent is then attached to the monoclonal antibody using a chemical linker. The design and development of an ADC protein involves a complex process of selecting the appropriate monoclonal antibody and cytotoxic agent, optimizing the chemical linker, and conducting preclinical studies to assess safety and efficacy.

How is ADC protein administered to patients? 03/20/2018

ADC protein-based immunotherapy is usually administered through intravenous infusion. The dosage and treatment schedule will vary depending on the specific type of ADC protein being used and the patient's individual cancer treatment plan.

What types of cancer can be treated with ADC protein-based immunotherapy? 08/09/2016

ADC protein-based immunotherapy has been studied in a variety of cancer types, including breast cancer, lung cancer, ovarian cancer, and Hodgkin's lymphoma. The specific type of ADC protein used may vary depending on the type and stage of cancer.

Is ADC protein-based immunotherapy used as a standalone treatment or in combination with other treatments? 08/01/2016

ADC protein-based immunotherapy is often used in combination with other cancer treatments, such as chemotherapy or radiation therapy. The combination treatment approach may help to enhance the effectiveness of ADC protein-based immunotherapy.

What are the potential side effects of ADC protein-based immunotherapy? 05/02/2016

The side effects of ADC protein-based immunotherapy can vary depending on the specific type of ADC protein being used and the individual patient. Some common side effects include infusion related reactions such as fever, chills, and nausea. More serious side effects can include damage to healthy cells and tissues, nerve damage, and low blood cell counts. Patients should be closely monitored for any adverse reactions and treated accordingly.

What types of cancer can ADC protein-based immunotherapy be used to treat? 01/13/2016

ADC protein-based immunotherapy can potentially be used to treat a variety of cancers, as long as there are specific targets or antigens expressed on the surface of cancer cells that can be targeted by the ADC protein. Some examples of cancers that have been successfully treated with ADC protein-based immunotherapy include breast cancer, lung cancer, and lymphoma.

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