ADC
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Official Full Name
arginine decarboxylase
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Overview
Arginine decarboxylase is an enzyme that in humans is encoded by the ADC gene. -
Synonyms
ADC; arginine decarboxylase; KIAA1945; ODC p; ODC1L; ornithine decarboxylase like; L-Arginine carboxy lyase; ODC paralog; ODCp; ARGDC; ODC-paralogue; antizyme inhibitor 2; ODC antizyme inhibitor-2; ornithine decarboxylase-paralog; ornithine decarboxylase-like protein; AZI2; ODC-p;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ADC-319H | Recombinant Human ADC Protein, GST-tagged | Wheat Germ | GST | ||
Human | ADC-9403H | Recombinant Human ADC, GST-tagged | E.coli | GST | 251-460a.a. | |
Human | ADC-901HF | Recombinant Full Length Human ADC Protein, GST-tagged | In Vitro Cell Free System | GST | 460 amino acids | |
Chicken | ADC-5591C | Recombinant Chicken ADC | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ADC Related Articles
ADC involved in several pathways and played different roles in them. We selected most pathways ADC participated on our site, such as Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Arginine and proline metabolism | MAOA;AZIN2;PRODH;P4HA1A;P4HA1B;HOGA1;SAT1;ALDH2;ALDH9A1 |
Metabolic pathways | GALM;AK1;AOX4;HADHB;IMPDH2;IDO1;TST;UMPS;B3GAT3 |
ADC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ADC itself. We selected most functions ADC had, and list some proteins which have the same functions with ADC. You can find most of the proteins on our site.
Function | Related Protein |
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ADC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADC here. Most of them are supplied by our site. Hope this information will be useful for your research of ADC.
- Q&As
- Reviews
Q&As (12)
Ask a questionADC protein-based immunotherapy works by using a targeted approach to deliver a potent cytotoxic drug directly to cancer cells while sparing healthy cells. The ADC protein is designed to recognize and bind to specific antigens expressed on the surface of cancer cells. Once bound, the ADC protein is internalized by the cancer cell and the cytotoxic drug is released, causing damage to the cancer cell and eventually leading to cell death.
The effectiveness of ADC protein-based immunotherapy can vary depending on the specific type of cancer being treated, the patient's individual cancer profile, and the characteristics of the ADC protein being used. However, some studies have shown significant improvement in overall survival and disease progression in patients treated with ADC protein-based immunotherapy compared to traditional cancer treatments alone. Further research is needed to fully assess the potential of ADC protein-based immunotherapy as a viable treatment option for cancer.
ADC protein-based immunotherapy is typically administered through an intravenous infusion, meaning that the treatment is delivered directly into the patient's bloodstream. The treatment may be administered on an outpatient basis, or the patient may need to stay in the hospital for monitoring during their initial treatment.
The duration of ADC protein-based immunotherapy can vary depending on the individual patient and the specific type of ADC protein being used. Some patients may require multiple cycles of treatment over the course of several months or years. The treatment schedule is typically determined based on the patient's response to treatment and the likelihood of disease recurrence.
ADC protein-based immunotherapy may cause a range of side effects, including fever, chills, fatigue, nausea, vomiting, and diarrhea. More serious side effects may include heart problems, liver damage, and bleeding disorders. However, the specific side effects of ADC protein-based immunotherapy can vary depending on the individual patient and the specific type of ADC protein being used.
Yes, ADC protein-based immunotherapy can be used in combination with other cancer treatments such as chemotherapy and radiation therapy. Combination therapy can potentially produce better treatment outcomes than monotherapy alone.
The ADC protein is typically designed using a combination of monoclonal antibodies and cytotoxic agents. The monoclonal antibody portion of the ADC protein is engineered to recognize and bind to specific antigens expressed on cancer cells. The cytotoxic agent is then attached to the monoclonal antibody using a chemical linker. The design and development of an ADC protein involves a complex process of selecting the appropriate monoclonal antibody and cytotoxic agent, optimizing the chemical linker, and conducting preclinical studies to assess safety and efficacy.
ADC protein-based immunotherapy is usually administered through intravenous infusion. The dosage and treatment schedule will vary depending on the specific type of ADC protein being used and the patient's individual cancer treatment plan.
ADC protein-based immunotherapy has been studied in a variety of cancer types, including breast cancer, lung cancer, ovarian cancer, and Hodgkin's lymphoma. The specific type of ADC protein used may vary depending on the type and stage of cancer.
ADC protein-based immunotherapy is often used in combination with other cancer treatments, such as chemotherapy or radiation therapy. The combination treatment approach may help to enhance the effectiveness of ADC protein-based immunotherapy.
The side effects of ADC protein-based immunotherapy can vary depending on the specific type of ADC protein being used and the individual patient. Some common side effects include infusion related reactions such as fever, chills, and nausea. More serious side effects can include damage to healthy cells and tissues, nerve damage, and low blood cell counts. Patients should be closely monitored for any adverse reactions and treated accordingly.
ADC protein-based immunotherapy can potentially be used to treat a variety of cancers, as long as there are specific targets or antigens expressed on the surface of cancer cells that can be targeted by the ADC protein. Some examples of cancers that have been successfully treated with ADC protein-based immunotherapy include breast cancer, lung cancer, and lymphoma.
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