adipor1
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  • Official Full Name
  • adiponectin receptor 1
  • Background
  • This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
  • Synonyms
  • ADIPOR1; adiponectin receptor 1; CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A; adiponectin receptor protein 1; progestin and adipoQ receptor family member I;
Cat.#:ADIPOR1-22HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOR1 protein, MYC/DDK-tagged
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Cat.#:ADIPOR1-3199HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOR1, His-tagged, MBP tagged
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Cat.#:ADIPOR1-358HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADK Protein, GST-tagged
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Cat.#:ADIPOR1-557HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOR1 protein, His & MBP-tagged
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Cat.#:ADIPOR1-609HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOR1 protein, His & GST-tagged
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Cat.#:ADIPOR1-625HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADIPOR1, GST-tagged
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Cat.#:ADIPOR1-626HTag:His/SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOR1 protein, His/SUMO-tagged
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Cat.#:ADIPOR1-9426HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOR1, GST-tagged
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Cat.#:ADIPOR1-248RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADIPOR1 Protein, His-tagged
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Cat.#:ADIPOR1-2707CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADIPOR1
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Involved Pathway

ADIPOR1 involved in several pathways and played different roles in them. We selected most pathways ADIPOR1 participated on our site, such as AMPK signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with ADIPOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AMPK signaling pathway
TSC2; PPARGC1A; IRS1; PCK2; HMGCR; G6PC3; PCK1; HNF4A; AKT3; ADIPOR2
Adipocytokine signaling pathway
AGRP; POMC; PTPN11A; CPT1B; NPY; AKT1; PCK1; SLC2A1A; PPARGC1A; PRKAG3
Non-alcoholic fatty liver disease (NAFLD)
LEPR; NDUFA5; AKT2; NDUFA1; NDUFV3; ATF4; PRKAG3; SDHB; MAP3K11; COX5A

Protein Function

ADIPOR1 has several biochemical functions, for example, adipokinetic hormone receptor activity, adiponectin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADIPOR1 itself. We selected most functions ADIPOR1 had, and list some proteins which have the same functions with ADIPOR1. You can find most of the proteins on our site.
Function
Related Protein
Function adipokinetic hormone receptor activity
Related Protein ADIPOR1; ADIPOR2
Function adiponectin binding
Related Protein ADIPOR1; CDH13; ADIPOR2
Function identical protein binding
Related Protein TRIM5; Serpina1c; MICU1; BIN1; PPP5C; KCNH2; VPS41; PTS; PITX2; HTT
Function metal ion binding
Related Protein RFNG; FOXP1; DSG1A; GNA15; TEC; SMAD5; B4GALT4; GALNTL4; ZHX1; GALNT5
Function protein heterodimerization activity
Related Protein TRP53; TOP2B; SMC2; MAPK6; H2AFVB; TYRP1; HNF1A; AOC3; BIRC5; ERBB3
Function protein kinase binding
Related Protein TRP53; ZBTB4; PTPN23; NPM1; CAMK2N1; PPP1CB; POLA1; EMP2; PRDX3; SQSTM1
Function receptor activity
Related Protein TREM1; ANTXR2B; NLGN2; ATRN; ICAM1; ADIPOR1B; ATP6AP2; HTR3A; RET; SEC63

Interacting Protein

ADIPOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADIPOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADIPOR1.
APPL1; NAA20; STK11; ynbB; DPH3; NFKBIL1; MYC

ADIPOR1 Related Articles

Su, YC; Xiang, RL; et al. Decreased submandibular adiponectin is involved in the progression of autoimmune sialoadenitis in non-obese diabetic mice. ORAL DISEASES 20:744-755(2014).
Li, JH; Su, SY; et al. Analysis of the association between adiponectin, adiponectin receptor 1 and diabetic cardiomyopathy. EXPERIMENTAL AND THERAPEUTIC MEDICINE 7:1023-1027(2014).