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AFM

  • Official Full Name

    afamin

  • Overview

    This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.
  • Synonyms

    AFM; afamin; ALB2; ALBA; AFAM_HUMAN; ALB 2; Alpha albumin; Alpha-Alb; Alpha-albumin; ALF;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AFM-145H Recombinant Human AFM, His tagged Human Cell Fc/His
Human AFM-410H Recombinant Human AFM Protein, GST-tagged Wheat Germ GST
Human AFM-794HCL Recombinant Human AFM cell lysate Human Cell N/A
Human AFM-1087H Recombinant Human AFM protein(Met1-Asn599), His-tagged HEK293 C-His Met1-Asn599
Human AFM-15HF Recombinant Full Length Human AFM Protein In Vitro Cell Free System 599 amino acids
Human AFM-497H Recombinant Human AFM Protein, His-tagged E.coli His Leu22~Thr210
Human AFM-26448TH Recombinant Human AFM Wheat Germ N/A 599 amino acids
Human AFM-0457H Recombinant Human AFM Protein (Leu22-Thr210), His-tagged E.coli His Leu22-Thr210
Human AFM-991HF Recombinant Full Length Human AFM Protein, GST-tagged In Vitro Cell Free System GST 599 amino acids
Mouse AFM-1402M Recombinant Mouse AFM Protein Mammalian Cell His
Mouse AFM-377M-B Recombinant Mouse AFM Protein Pre-coupled Magnetic Beads HEK293
Mouse AFM-377M Recombinant Mouse AFM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Afm-499M Recombinant Mouse Afm Protein, His-tagged E.coli His Thr210~Glu403
Rat Afm-3235R Recombinant Rat Afm, His-tagged E.Coli or Yeast His 608
Rat AFM-554R Recombinant Rat AFM Protein Mammalian Cell His
Rat AFM-210R Recombinant Rat AFM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AFM-210R-B Recombinant Rat AFM Protein Pre-coupled Magnetic Beads HEK293
Rat Afm-91R Recombinant Rat Afm Protein, His-tagged E.coli N-His Leu22-Tyr201
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AFM Related Articles

AFM involved in several pathways and played different roles in them. We selected most pathways AFM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AFM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AFM has several biochemical functions, for example, vitamin E binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AFM itself. We selected most functions AFM had, and list some proteins which have the same functions with AFM. You can find most of the proteins on our site.

Function Related Protein
vitamin E bindingSEC14L2;TTPA;AFM

AFM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AFM here. Most of them are supplied by our site. Hope this information will be useful for your research of AFM.

Huebner, M; Ben Haddada, M; et al. Layer-by-layer generation of PEG-based regenerable immunosensing surfaces for small-sized analytes. BIOSENSORS & BIOELECTRONICS 67:334-341(2015).
Li, P; Zhang, Y; et al. Development of chemiluminescent enzyme immunoassay for the determination of aflatoxin M-1 in milk products. FOOD AND AGRICULTURAL IMMUNOLOGY 26:157-169(2015).
  • Q&As
  • Reviews

Q&As (10)

Ask a question
How does AFM protein contribute to cellular processes such as cell adhesion, migration, or signaling pathways, and what are the underlying molecular mechanisms? 01/18/2023

AFM protein plays a role in cellular processes such as cell adhesion, migration, or signaling pathways, and the underlying molecular mechanisms can be investigated using techniques like siRNA knockdown, gene overexpression, or functional assays.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or function of AFM protein? 06/08/2022

Post-translational modifications or regulatory mechanisms may modulate the activity or function of AFM protein, and these can be studied through site-directed mutagenesis, phosphoproteomics analysis, or biochemical assays.

What are the downstream signaling pathways or cellular responses triggered by AFM protein activation, and how can these be studied experimentally? 05/15/2022

Downstream signaling pathways or cellular responses triggered by AFM protein activation can be studied through techniques such as Western blotting, gene expression analysis, or functional assays specific to the signaling pathways of interest.

What is the cellular localization of AFM protein, and how can it be experimentally determined? 10/18/2021

The cellular localization of AFM protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.

What is the role of AFM protein in tissue development, organogenesis, or disease progression, and how can its function be studied in relevant model systems? 10/08/2019

The role of AFM protein in tissue development, organogenesis, or disease progression can be explored using model systems such as animal models, organoid cultures, or tissue engineering approaches.

What are the binding partners or interacting molecules of AFM protein, and how can these interactions be characterized? 01/26/2019

The binding partners or interacting molecules of AFM protein can be identified through approaches like co-immunoprecipitation, protein-protein interaction assays, or mass spectrometry.

Can AFM protein be targeted or manipulated to modulate cell behavior or tissue regeneration, and what experimental strategies can be used to assess its therapeutic potential? 11/24/2018

Modulating AFM protein activity or expression may have implications for cell behavior or tissue regeneration, and the therapeutic potential can be assessed using in vitro or in vivo models combined with functional assays or tissue engineering approaches.

Are there any genetic variations or mutations in the gene encoding AFM protein that impact its expression or function, and what are the implications for cellular phenotypes or disease susceptibility? 12/11/2017

Genetic variations or mutations in the gene encoding AFM protein may impact its expression or function, leading to altered cellular phenotypes or disease susceptibility, and these can be investigated through genetic association studies or functional characterization of mutant variants.

How does AFM protein affect cellular biomechanics, such as cell stiffness, contractility, or cytoskeletal organization, and what are the experimental approaches to investigate these effects? 11/12/2017

AFM protein influences cellular biomechanics, and its effects on cell stiffness, contractility, or cytoskeletal organization can be investigated through techniques like atomic force microscopy, traction force microscopy, or cytoskeletal staining.

How does dysregulation or dysfunction of AFM protein contribute to pathologies or disease conditions, and what experimental models or techniques can be employed to investigate these associations? 07/16/2016

Dysregulation or dysfunction of AFM protein contributes to pathologies or disease conditions, and associations can be investigated using disease models, patient samples, or genetically modified systems, combined with phenotypic assessments or molecular analysis techniques.

Customer Reviews (3)

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Reviews
10/22/2022

    Probing protein-protein interactions in chromatin modifications for gene regulation.

    03/07/2022

      Deciphering protein-protein interactions in mitochondrial function for cellular energy production.

      08/02/2018

        Studying protein-protein interactions in apoptosis pathways for programmed cell death.

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