Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

AMBN

  • Official Full Name

    ameloblastin (enamel matrix protein)

  • Overview

    This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect.
  • Synonyms

    AMBN; ameloblastin (enamel matrix protein); ameloblastin, enamel matrix protein; ameloblastin; AMBN_HUMAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AMBN-514H Recombinant Human AMBN protein, GST-tagged Wheat Germ GST
Human AMBN-69HCL Recombinant Human AMBN cell lysate N/A
Human AMBN-1855H Recombinant Human AMBN Protein (27-447 aa), His-tagged Yeast His 27-447 aa
Human AMBN-17HF Recombinant Full Length Human AMBN Protein In Vitro Cell Free System 447 amino acids
Human AMBN-0104H Recombinant Human AMBN Protein (Val27-Pro447), C-His-tagged Mammalian cells C-His Val27-Pro447
Human AMBN-1022H Recombinant Human AMBN Protein, His-tagged HEK293 His
Human AMBN-1016HF Recombinant Full Length Human AMBN Protein, GST-tagged In Vitro Cell Free System GST 447 amino acids
Human AMBN-27234TH Recombinant Human AMBN Wheat Germ N/A 447 amino acids
Mouse Ambn-351M Active Recombinant Mouse Ambn, His-tagged Mammalian cells His
Mouse AMBN-1588M Recombinant Mouse AMBN Protein Mammalian Cell His
Mouse Ambn-3405M Recombinant Mouse Ambn, His-tagged E.Coli or Yeast His 407
Mouse Ambn-498M Recombinant Mouse Ambn Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ambn-498M-B Recombinant Mouse Ambn Protein Pre-coupled Magnetic Beads HEK293
Rat AMBN-645R Recombinant Rat AMBN Protein Mammalian Cell His
Rat AMBN-301R-B Recombinant Rat AMBN Protein Pre-coupled Magnetic Beads HEK293
Rat AMBN-301R Recombinant Rat AMBN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AMBN Related Articles

AMBN involved in several pathways and played different roles in them. We selected most pathways AMBN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMBN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AMBN has several biochemical functions, for example, growth factor activity, structural constituent of tooth enamel. Some of the functions are cooperated with other proteins, some of the functions could acted by AMBN itself. We selected most functions AMBN had, and list some proteins which have the same functions with AMBN. You can find most of the proteins on our site.

Function Related Protein
growth factor activityTIMP1;FIGF;Kitl;GDF6B;MSTNB;ANGPTL3;VEGFAB;GDF9;PDGFA
structural constituent of tooth enamelAMELY;AMBN;STATH;TUFT1;AMELX

AMBN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMBN here. Most of them are supplied by our site. Hope this information will be useful for your research of AMBN.

Kiyoshima, T; Nagata, K; et al. Immunohistochemical expression of thymosin beta 4 in ameloblastomas and odontomas. HISTOLOGY AND HISTOPATHOLOGY 28:775-786(2013).
Hatakeyama, J; Fukumoto, S; et al. Synergistic Roles of Amelogenin and Ameloblastin. JOURNAL OF DENTAL RESEARCH 88:318-322(2009).
  • Q&As
  • Reviews

Q&As (10)

Ask a question
Can AMBN be used as a biomarker for enamel defects or dental disorders, and what are the diagnostic implications of its expression patterns? 09/05/2022

AMBN expression patterns and levels can serve as biomarkers for enamel defects or dental disorders, providing diagnostic information about the integrity and quality of the enamel layer.

Can AMBN-derived peptides or fragments be used as therapeutic agents for enamel repair or regeneration? 04/09/2021

AMBN-derived peptides or fragments may have potential as therapeutic agents for enamel repair or regeneration, promoting enamel formation or stimulating the differentiation of dental stem cells.

How does AMBN contribute to the mechanical properties of enamel, such as hardness, resilience, and resistance to wear? 10/05/2020

AMBN contributes to the mechanical properties of enamel, such as its hardness, resilience, and resistance to wear, through its organization and interaction with other enamel proteins.

What are the consequences of AMBN mutations or genetic variations on enamel formation and tooth integrity, and how do these variations contribute to dental phenotypes or disorders? 08/05/2019

Mutations or genetic variations in the AMBN gene can lead to enamel defects and dental phenotypes, highlighting the importance of AMBN in enamel formation and integrity.

What are the post-translational modifications of AMBN, such as phosphorylation or glycosylation, and how do these modifications influence its function and assembly into the developing enamel matrix? 04/26/2019

AMBN undergoes post-translational modifications, including phosphorylation and glycosylation, which play a role in its functional properties and assembly into the developing enamel matrix.

What are the mechanisms underlying AMBN secretion and transport to the enamel matrix, and how can these processes be modulated for therapeutic interventions in enamel-related disorders? 03/14/2019

The secretion and transport of AMBN to the enamel matrix involve specific mechanisms, including vesicular trafficking and protein-protein interactions, which can be targeted for therapeutic interventions in enamel-related disorders.

How does AMBN interact with dental stem cells or progenitor cells, and what is its role in tooth regeneration or repair processes? 09/19/2018

AMBN interacts with dental stem cells or progenitor cells, influencing their differentiation and contributing to tooth regeneration or repair processes.

What are the key signaling pathways or regulatory factors that control AMBN expression and secretion during tooth development? 06/24/2018

The expression and secretion of AMBN during tooth development are regulated by various signaling pathways, including those involving transcription factors, growth factors, and extracellular matrix components.

How does AMBN interact with other enamel matrix proteins, such as amelogenin and enamelin, and what are the functional consequences of these interactions? 10/04/2017

AMBN interacts with other enamel matrix proteins, such as amelogenin and enamelin, forming a complex network that contributes to the formation of the enamel matrix and its subsequent mineralization.

What is the role of AMBN in enamel development, and how does it contribute to enamel mineralization and structure? 09/07/2017

AMBN is a critical protein involved in enamel development and is responsible for regulating enamel mineralization and determining the structure and hardness of the enamel layer.

Customer Reviews (3)

Write a review
Reviews
08/09/2022

    Reduced assay interference from complex sample backgrounds.

    02/20/2022

      High-throughput screening compatibility for rapid data generation.

      08/17/2020

        Reliable detection of protein localization and trafficking.

        Ask a Question for All AMBN Products

        Required fields are marked with *

        My Review for All AMBN Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends