aox1
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  • Official Full Name
  • aldehyde oxidase 1
  • Background
  • Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis.
  • Synonyms
  • AOX1; aldehyde oxidase 1; aldehyde oxidase; AO; AOH1
Cat.#:AOX1-329HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AOX1 Protein (236-421 aa), His-tagged
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Cat.#:AOX1-18HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human AOX1 protein, MYC/DDK-tagged
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Cat.#:Aox1-3266MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Aox1, His-tagged
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Cat.#:AOX1-694RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AOX1 Protein
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Cat.#:AOX1-300CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus AOX1 Protein, His-tagged
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Cat.#:AOX1-341RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey AOX1 Protein, His-tagged
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Cat.#:AOX1-3316CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AOX1
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Cat.#:AOX1-8315ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AOX1
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Cat.#:AOX1-8821HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human AOX1 293 Cell Lysate
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Involved Pathway

AOX1 involved in several pathways and played different roles in them. We selected most pathways AOX1 participated on our site, such as Valine, leucine and isoleucine degradation, Tyrosine metabolism, Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Valine, leucine and isoleucine degradation
AOX3L1; AOX1; ALDH3A2; ALDH1B1; BCAT2; HMGCLL1; ACADM; AOX4; HMGCL; HADHAB
Tyrosine metabolism
ALDH3B1; GOT1; MAOA; FAH; HGD; AOX4; AOX1; DCT; COMTA; HPDA
Tryptophan metabolism
ANI_1_2390104; HADH; GCDHB; AOX2P; ALDH2.1; INMT; MAOA; OGDHL; ACAT2; TDO2B
Vitamin B metabolism
PDXP; AOX2P; PSAT1; AOX3L1; PDXK; AOX4; PDXKB; PNPO; AOX1; PHOSPHO2
Nicotinate and nicotinamide metabolism
NT5C1AA; NT5C3L; BST1; NT5C; PNP6; MIBP2; NADK2; NAPRT; NT5M; NADKD1
Retinol metabolism
BCO1L; LRATA; CYP2C37; CYP3A25; ALDH1A1; BCO1; CYP2C18; DGAT1; CYP4A12A; UGT1AB
Drug metabolism - cytochrome P
FMO5; UGT2B15; ALDH3A1; GSTM5; GSTAL; ALDH3B1; GSTP2; GSTA3; MGST1.1; UGT1A7C
Metabolic pathways
B4GALT4; UPP2; DPM1; DGAT1A; HSD17B1; CMPK1; DGAT2; CERS4; UGT2B15; INPP5B
Jak-STAT signaling pathway
IFNB1; SOCS5B; IFNW1; IFNG1-2; Gh; RNF207B; STAM2; IL13RA1; PRLR; NT5C3

Protein Function

AOX1 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, NAD binding, aldehyde oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AOX1 itself. We selected most functions AOX1 had, and list some proteins which have the same functions with AOX1. You can find most of the proteins on our site.
Function
Related Protein
Function 2 iron, 2 sulfur cluster binding
Related Protein FDX1B; ISCUB; FDX1; AIFM4; RFESD; SDHB; GLRX2; CISD2; CISD3; AIFM3
Function NAD binding
Related Protein GAPDH; AOX3; HSD11B2; AHCY; GPD1C; GPD1; NNT; GRHPR; LDHA; PARP1
Function aldehyde oxidase activity
Related Protein AOX4; AOX3L1; AOX1; ADH7; AOX3
Function electron carrier activity
Related Protein NDUFS1; GLRX3; GPX2; COX11; GCDHA; ACADL; GLRX; ACAD11; ADH5; IDH3B
Function flavin adenine dinucleotide binding
Related Protein GFER; AOX3L1; AIFM3; SQLEA; DHCR24; TXNRD3; NOS1; ACAD9; ETFA; MAOA
Function iron ion binding
Related Protein PPEF2; PAH; FDX1; HBD; CYP2V1; TPH1A; JMJD6; EGLN3; TYW5; CYP2A7
Function molybdopterin cofactor binding
Related Protein AOX1; MARC1; SUOX; XDH; MOSC2; MARC2
Function oxidoreductase activity, acting on CH-OH group of donors
Related Protein AOX3L1; AOX4; DHCR24; AGPS; XDH; AOX3; AOX1; GULO
Function xanthine dehydrogenase activity
Related Protein AOX1; XDH

Interacting Protein

AOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AOX1.
RBL1; GK; CRKL; RCHY1

AOX1 Related Articles

Kim, S; Warburton, S; et al. Regulation of alcohol oxidase 1 (AOX1) promoter and peroxisome biogenesis in different fermentation processes in Pichia pastoris. JOURNAL OF BIOTECHNOLOGY 166:174-181(2013).
Tu, YB; Wang, YQ; et al. High-level expression and immunogenicity of a porcine circovirus type 2 capsid protein through codon optimization in Pichia pastoris. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 97:2867-2875(2013).